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NCT07424365 · ClinicalTrials.gov registry record · NA
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
A NA study of Parkinsons Disease (PD) and Mild Cognitive Impairment (MCI), sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT07424365: Recruiting NA study of Parkinsons Disease (PD) and Mild Cognitive Impairment (MCI), sponsored by University of Colorado, Denver.
NCT07424365 is a NA study of Parkinsons Disease (PD) and Mild Cognitive Impairment (MCI) that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 80 participants, below the 115-participant average among 19 other Parkinsons Disease (PD) trials with a reported enrollment target (30% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07424365, a NA study of Parkinsons Disease (PD) and Mild Cognitive Impairment (MCI), is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve brain function in both healthy individuals and people with Parkinson's disease (PD).
Primary Outcome
a lack of AEs and SAEs during the paired-taVNS intervention
Conditions Studied
Interventions
- DEVICE transcutaneous auricular vagus nerve stimulation
- DEVICE sham stimulation
Study Locations (1)
Colorado
- Clinical Translational Research Center at CU Anschutz - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-05-19 |
| Est. Completion | 2028-05 |
| Phase | NA |
What NCT07424365 shows while recruiting
NCT07424365 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 115-participant average among 19 other Parkinsons Disease (PD) trials with a reported enrollment target (30% lower).
The record links to 3 conditions, with Parkinsons Disease (PD) appearing as the primary indexed condition, and to 2 interventions - of which transcutaneous auricular vagus nerve stimulation is the first listed.
NCT07424365 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT07424365 about?
NCT07424365 is a clinical study titled "Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations". This study plans to learn more about how stimulating the vagus nerve through gentle electrical stimulation applied to the ear can affect decision-making, problem-solving, and other thinking abilities. This process, called transcutaneous auricular vagus nerve stimulation (taVNS), could help improve b...
What is the current status of trial NCT07424365?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2025-05-19. Estimated completion is 2028-05.
What conditions does trial NCT07424365 study?
This clinical trial studies the following conditions: Parkinsons Disease (PD), Mild Cognitive Impairment (MCI), Healthy Adult.
What interventions are being tested in trial NCT07424365?
The interventions under investigation include: transcutaneous auricular vagus nerve stimulation (DEVICE), sham stimulation (DEVICE).
Who is sponsoring clinical trial NCT07424365?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07424365 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinsons Disease (PD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07424365's enrollment target sits among peer trials
80 8th of 19 higher than 11 of 19 other Parkinsons Disease (PD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinsons Disease (PD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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