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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Papillary Renal Cell Carcinoma: early-phase trial registry

2 of 9 indexed Papillary Renal Cell Carcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 2 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Papillary Renal Cell Carcinoma: 9 US clinical trials tracked, 2 recruiting.

Papillary Renal Cell Carcinoma is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 2 of these trials.

Enrollment posture brief

Registry condition papillary-renal-cell-carcinoma

OPEN 2 | RECR 22% | LATE 1 | EARLY 6 | RANK #1916 | SPON 2

Nearest open-share peer: Acne (22% recruiting · 27 trials)

Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Acute Otitis Media22.2%Papillary Renal Cell Car (th…22%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Papillary Renal Cell Carcinoma

Papillary Renal Cell Carcinoma lists 2 open slots (22% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Papillary Renal Cell Carcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Papillary Renal Cell Carcinoma is recruiting below its size-band peers.

    2 of 9 indexed trials (22.2%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Papillary Renal Cell Carcinoma research.

    National Cancer Institute (NCI) accounts for 2 of 9 trials (22.2%). 8 distinct sponsors appear on at least one study for this condition label.

  3. Typical Papillary Renal Cell Carcinoma enrolment sits around 134 participants.

    Median target enrolment is 134 among the 9 trials that report a genuine target (sentinel values excluded). 4 of those (44.4%) plan for fewer than 100 participants.

  4. Papillary Renal Cell Carcinoma research is mostly interventional.

    8 interventional and 1 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 26Phase 31

Open and recent trials

9 total, page 1 of 1

RECRUITING NA 600 participants

An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

University of Texas Southwestern Medical Center

NCT04623502

RECRUITING Phase 2 65 participants

Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer

National Cancer Institute (NCI)

NCT04981509

ACTIVE NOT RECRUITING 589 participants

Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study

Mayo Clinic

NCT06339138

ACTIVE NOT RECRUITING Phase 3 148 participants

Savolitinib Plus Durvalumab Versus Sunitinib and Durvalumab Monotherapy in MET-Driven, Unresectable and Locally Advanced or Metastatic PRCC

AstraZeneca

NCT05043090

ACTIVE NOT RECRUITING Phase 2 134 participants

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study

National Cancer Institute (NCI)

NCT04071223

ACTIVE NOT RECRUITING Phase 2 60 participants

Cabozantinib In Combo With NIVO + IPI In Advanced NCCRCC

Bradley A. McGregor, MD

NCT04413123

ACTIVE NOT RECRUITING Phase 2 60 participants

A Study of Nivolumab In Combination With Cabozantinib in Patients With Non-Clear Cell Renal Cell Carcinoma

Memorial Sloan Kettering Cancer Center

NCT03635892

ACTIVE NOT RECRUITING Phase 2 32 participants

Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma

M.D. Anderson Cancer Center

NCT03541902

COMPLETED Phase 2 291 participants

Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors

Children's Oncology Group

NCT00335556

Phase Distribution

PhaseTrial count
Phase 2 6
Phase 3 1

Named interventions

Most-linked intervention names on Papillary Renal Cell Carcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cabozantinib Drug
2 trials
Bone Scan Procedure
2 trials
Biospecimen Collection Procedure
2 trials
cabozantinib Drug
1 trials
sunitinib Drug
1 trials
Sunitinib Malate Drug
1 trials
savolitinib Drug
1 trials
13C-Fructose Other
1 trials

US sites by state

Facility locations filed on Papillary Renal Cell Carcinoma trials. A trial with sites in several states counts in each.

Texas 4 trials
New York 3 trials
California 3 trials
New Jersey 2 trials
Massachusetts 2 trials
Illinois 2 trials
Alabama 2 trials
Pennsylvania 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Papillary Renal Cell Carcinoma page

9 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Papillary Renal Cell Carcinoma condition card totals 9 registered trials; most-linked intervention Cabozantinib; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.