Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Acute Respiratory Distress Syndrome (ARDS): early-phase trial registry

5 of 9 indexed Acute Respiratory Distress Syndrome (ARDS) trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 5 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Acute Respiratory Distress Syndrome (ARDS): 9 US clinical trials tracked, 5 recruiting.

Acute Respiratory Distress Syndrome (ARDS) is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is PPD Development, running 4 of these trials.

Enrollment posture brief

Registry condition acute-respiratory-distress-syndrome-ards

OPEN 5 | RECR 56% | LATE 0 | EARLY 6 | RANK #1916 | SPON 4

Nearest open-share peer: Advanced Colorectal Cancer (56% recruiting · 9 trials)

Acute Spinal Cord Injury88.9%Acute Respiratory Distre (th…56%Acute Lymphoblastic Leukemia55.6%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome (ARDS) lists 5 open slots (56% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Acute Respiratory Distress Syndrome (ARDS) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Acute Respiratory Distress Syndrome (ARDS) is recruiting above its size-band peers.

    5 of 9 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Acute Respiratory Distress Syndrome (ARDS) research.

    PPD Development accounts for 4 of 9 trials (44.4%). 6 distinct sponsors appear on at least one study for this condition label.

  3. Typical Acute Respiratory Distress Syndrome (ARDS) enrolment sits around 200 participants.

    Median target enrolment is 200 among the 9 trials that report a genuine target (sentinel values excluded). 1 of those (11.1%) plan for fewer than 100 participants.

  4. Acute Respiratory Distress Syndrome (ARDS) research is mostly interventional.

    7 interventional and 2 observational studies make up this index (77.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 26

Open and recent trials

9 total, page 1 of 1

RECRUITING Phase 2 600 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

PPD Development

NCT06703073

RECRUITING Phase 2 200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

PPD Development

NCT06701656

RECRUITING Phase 2 200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

PPD Development

NCT06701682

RECRUITING Phase 2 200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

PPD Development

NCT06701669

RECRUITING Phase 2 160 participants

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

Children's Hospital of Philadelphia

NCT07123961

ACTIVE NOT RECRUITING 140,000 participants

An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States

Bayer

NCT06272942

ACTIVE NOT RECRUITING Phase 2 15 participants

Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS

Aqualung Therapeutics

NCT05938036

COMPLETED 367 participants

The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol

Yale University

NCT01714583

COMPLETED NA 139 participants

Pragmatic Investigation of Volume Targeted Ventilation-1

Wake Forest University Health Sciences

NCT03909854

Phase Distribution

PhaseTrial count
Phase 2 6

Named interventions

Most-linked intervention names on Acute Respiratory Distress Syndrome (ARDS) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cohort C: bevacizumab Drug
2 trials
Cohort B: placebo Drug
2 trials
Cohort B: paridiprubart Drug
2 trials
Cohort A: placebo Drug
2 trials
Cohort A: vilobelimab Drug
2 trials
mode of mechanical ventilation Procedure
1 trials
ALT-100 (Placebo) Drug
1 trials
ALT-100 mAb Drug
1 trials

US sites by state

Facility locations filed on Acute Respiratory Distress Syndrome (ARDS) trials. A trial with sites in several states counts in each.

New Jersey 5 trials
New York 4 trials
Nevada 4 trials
Minnesota 4 trials
Michigan 4 trials
Massachusetts 4 trials
Illinois 4 trials
Idaho 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Acute Respiratory Distress Syndrome (ARDS) page

9 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Acute Respiratory Distress Syndrome (ARDS) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • PPD Development sponsors the most Acute Respiratory Distress Syndrome (ARDS) trials on record, review their full trial history before evaluating a specific study. See PPD Development's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Respiratory Distress Syndrome (ARDS) condition card totals 9 registered trials; most-linked intervention Cohort C: bevacizumab; top US site state New Jersey. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.