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ClinicalTrials.gov 5 recruiting now official registry

Acute Respiratory Distress Syndrome (ARDS) clinical trials

5 of 9 indexed Acute Respiratory Distress Syndrome (ARDS) trials are currently recruiting.

9 US clinical trials · 5 currently recruiting

Acute Respiratory Distress Syndrome (ARDS) is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is PPD Development, running 4 of these trials.

The research picture

Acute Respiratory Distress Syndrome (ARDS) has 9 registered US clinical trials, 5 of them open to new participants right now, about 56% of the total.

5
recruiting participants now
56%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
4
top sponsor: PPD Development
Phase 26

Active & Recent Trials

9 total, page 1 of 1

RECRUITING Phase 2 600 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

PPD Development

NCT06703073

RECRUITING Phase 2 200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

PPD Development

NCT06701656

RECRUITING Phase 2 200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

PPD Development

NCT06701682

RECRUITING Phase 2 200 participants

JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

PPD Development

NCT06701669

RECRUITING Phase 2 160 participants

Pediatric Acute Respiratory Distress Syndrome (ARDS) Management Trial

Children's Hospital of Philadelphia

NCT07123961

ACTIVE NOT RECRUITING 140,000 participants

An Observational Study to Identify New Health Problems Arising After an Intensive Care Unit Admission in People With Acute Respiratory Distress Syndrome in the United States

Bayer

NCT06272942

ACTIVE NOT RECRUITING Phase 2 15 participants

Study of Safety and Efficacy of ALT-100mAb in Participants With Moderate/Severe ARDS

Aqualung Therapeutics

NCT05938036

COMPLETED 367 participants

The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol

Yale University

NCT01714583

COMPLETED NA 139 participants

Pragmatic Investigation of Volume Targeted Ventilation-1

Wake Forest University Health Sciences

NCT03909854

Phase Distribution

PhaseTrial count
Phase 2 6

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Acute Respiratory Distress Syndrome (ARDS) Trial Landscape

9 indexed Acute Respiratory Distress Syndrome (ARDS) studies · 5 recruiting (56%).

Phase mix: 0 late (III/IV) vs 6 early (I/II).

Top sponsor: PPD Development (4 trials), 5 others listed. 9 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Acute Respiratory Distress Syndrome (ARDS)?

PlainTrial tracks 9 US clinical trials for Acute Respiratory Distress Syndrome (ARDS), of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Acute Respiratory Distress Syndrome (ARDS)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.