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NCT03541902 · ClinicalTrials.gov registry record · Phase 2

Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma

A Phase 2 study of Renal Cell Carcinoma and Metastatic Renal Cell Carcinoma, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 2
Development phase
32
Enrollment target
3
Study locations

NCT03541902 is a Phase 2 study of Renal Cell Carcinoma and Metastatic Renal Cell Carcinoma that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 32 participants, below the 243-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (87% lower). The trial reports 3 study locations across 1 state.

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The verdict

NCT03541902, a Phase 2 study of Renal Cell Carcinoma and Metastatic Renal Cell Carcinoma, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
32 participants
Enrollment target
3
Study locations

Study Summary

The goal of this clinical research study is to compare the safety and effectiveness of cabozantinib and sunitinib when given to patients with metastatic (has spread) variant histology renal cell carcinoma (vhRCC), a type of kidney cancer. This is an investigational study. Cabozantinib and sunitinib are both FDA approved and commercially available for the treatment of advanced kidney cancer, including vhRCC. The study doctor can explain how the study drugs are designed to work. Up to 84 participants will be enrolled in this study. All will take part at MD Anderson.

Interventions

  • DRUG Cabozantinib
  • DRUG Sunitinib Malate

Study Locations (3)

Texas

  • M D Anderson Cancer Center - Houston
  • MD Anderson Regional Care Center-Katy - Houston
  • MD Anderson Regional Care Center-Sugar Land - Sugar Land

Trial Details

FieldValue
Enrollment Target 32 participants
Start Date 2018-05-15
Est. Completion 2027-07-31
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT03541902

The ClinicalTrials.gov registry entry for NCT03541902 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 32 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 243-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (87% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 9 conditions, with Renal Cell Carcinoma appearing as the primary indexed condition, and to 2 interventions - of which Cabozantinib is the first listed.

NCT03541902 reports 3 study locations spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03541902 about?

NCT03541902 is a clinical study titled "Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell Carcinoma". The goal of this clinical research study is to compare the safety and effectiveness of cabozantinib and sunitinib when given to patients with metastatic (has spread) variant histology renal cell carcinoma (vhRCC), a type of kidney cancer. This is an investigational study. Cabozantinib and sunitinib...

What is the current status of trial NCT03541902?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 32 participants. The study started on 2018-05-15. Estimated completion is 2027-07-31.

What conditions does trial NCT03541902 study?

This clinical trial studies the following conditions: Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8, Chromophobe Renal Cell Carcinoma, Papillary Renal Cell Carcinoma.

What interventions are being tested in trial NCT03541902?

The interventions under investigation include: Cabozantinib (DRUG), Sunitinib Malate (DRUG).

Who is sponsoring clinical trial NCT03541902?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03541902 being conducted?

This trial has 3 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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