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Pain Management: later-stage trial registry
13 of 32 indexed Pain Management trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #477 of 28,707 conditions by registered trial count.
32 US clinical trials · 13 currently recruiting · #477 of 28,707 conditions by registered trial count
Pain Management: 32 US clinical trials tracked, 13 recruiting.
Pain Management is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Pacira Pharmaceuticals, running 3 of these trials.
Enrollment posture brief
Registry condition pain-management
OPEN 13 | RECR 41% | LATE 9 | EARLY 5 | RANK #477 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Pain, Acute (41% recruiting · 32 trials)
Pain Management lists 13 open slots (41% of 32 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pain Management on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pain Management recruits in line with its size-band peers.
13 of 32 indexed trials (40.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Pain Management trials is spread across many organizations.
Pacira Pharmaceuticals accounts for 3 of 32 trials (9.4%). 26 distinct sponsors appear on at least one study for this condition label.
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Typical Pain Management enrolment sits around 105 participants.
Median target enrolment is 105 among the 32 trials that report a genuine target (sentinel values excluded). 14 of those (43.8%) plan for fewer than 100 participants.
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Pain Management research is mostly interventional.
31 interventional and 1 observational studies make up this index (96.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
32 total, page 1 of 1
Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention
Florida State University
NCT07335159
Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures
Albert Einstein College of Medicine
NCT07032766
Suzetrigine in Total Hip Arthroplasty
Hospital for Special Surgery, New York
NCT07226700
R.E.C.K vs Exparel in Robotic Nephrectomy
Wake Forest University Health Sciences
NCT07092566
The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair
Montefiore Medical Center
NCT07076069
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
Mohsen Saidinejad
NCT07369024
Post-Operative Analgesic Selection in Patients Planned for Third Molar Extraction After Undergoing Shared Decision Making Using 2- Versus 3-Option Decision-Aids
Rutgers, The State University of New Jersey
NCT07011472
Efficacy of Methylprednisolone for Pain Control After ACL Repair
St. Louis University
NCT07158476
Local Anesthesia for Facial Fractures
Washington University School of Medicine
NCT06429501
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
University of Iowa
NCT07032350
mHealth Intervention for Pain Self Management
Virginia Commonwealth University
NCT07332377
Psilocybin in Cancer Pain Study
Yvan Beaussant, MD, MSci
NCT06001749
Sensory Spinal Cord Stimulation
University of North Carolina, Chapel Hill
NCT07095036
Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty
Avenue Therapeutics
NCT03774836
PEACE: Comparing Chronic Pain Treatment Options
Memorial Sloan Kettering Cancer Center
NCT02979574
Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection
Memorial Sloan Kettering Cancer Center
NCT02523443
COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Oregon Health and Science University
NCT05492903
Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management
University of Texas at Austin
NCT07160049
Opioid-Free Orthopaedic Surgery
OrthoCarolina Research Institute
NCT04176783
The Alabama NSAIDs Patient Safety Survey, Phase II: Reducing Disparities in Risk Awareness and Communication
University of Alabama at Birmingham
NCT01352832
Tramadol Versus Placebo in the Management of Postoperative Pain Following Bunionectomy
Avenue Therapeutics
NCT03290378
Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section
Pacira Pharmaceuticals
NCT03853694
Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty
Pacira Pharmaceuticals
NCT05139030
Post-partum Non-pharmacologic Pain Management
Wright State University
NCT03903172
Effectiveness of External Vibration for Pain Relief During Intravenous Access in Adult Patients
Kyle Stein
NCT03619135
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation
Ashley Turner, MD
NCT03868787
Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
University of California, Irvine
NCT02276495
PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery
Pacira Pharmaceuticals
NCT02985762
Erector Spinae Regional Anesthesia for Pain Control
The University of Texas Health Science Center at San Antonio
NCT05794828
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
The University of Texas Health Science Center, Houston
NCT04750525
Combined Peripheral (BreEStim) and Central Electrical Stimulation (tDCS) for Neuropathic Pain Management - Spinal Cord Injury
The University of Texas Health Science Center, Houston
NCT03302793
BreEStim and tDCS for Neuropathic Pain Management - Healthy Subjects
The University of Texas Health Science Center, Houston
NCT03302780
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 3 |
| Phase 3 | 6 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Pain Management records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pain Management trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pain Management page
32 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 13 Pain Management trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Pacira Pharmaceuticals sponsors the most Pain Management trials on record, review their full trial history before evaluating a specific study. See Pacira Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pain Management condition card totals 32 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.