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Pain Management
Open-data reference.
32 US clinical trials · 13 currently recruiting
Active & Recent Trials
Does Patient Testimonial Improve the Pain Relief Derived From a Brief Intervention
Florida State University
NCT07335159
Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures
Albert Einstein College of Medicine
NCT07032766
Suzetrigine in Total Hip Arthroplasty
Hospital for Special Surgery, New York
NCT07226700
R.E.C.K vs Exparel in Robotic Nephrectomy
Wake Forest University Health Sciences
NCT07092566
The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair
Montefiore Medical Center
NCT07076069
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
Mohsen Saidinejad
NCT07369024
Post-Operative Analgesic Selection in Patients Planned for Third Molar Extraction After Undergoing Shared Decision Making Using 2- Versus 3-Option Decision-Aids
Rutgers, The State University of New Jersey
NCT07011472
Efficacy of Methylprednisolone for Pain Control After ACL Repair
St. Louis University
NCT07158476
Local Anesthesia for Facial Fractures
Washington University School of Medicine
NCT06429501
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
University of Iowa
NCT07032350
mHealth Intervention for Pain Self Management
Virginia Commonwealth University
NCT07332377
Psilocybin in Cancer Pain Study
Yvan Beaussant, MD, MSci
NCT06001749
Sensory Spinal Cord Stimulation
University of North Carolina, Chapel Hill
NCT07095036
Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty
Avenue Therapeutics
NCT03774836
PEACE: Comparing Chronic Pain Treatment Options
Memorial Sloan Kettering Cancer Center
NCT02979574
Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Liver Resection
Memorial Sloan Kettering Cancer Center
NCT02523443
COMmunity of Practice And Safety Support for Navigating Pain (COMPASS-NP)
Oregon Health and Science University
NCT05492903
Wearable Focused Ultrasound Stimulation for Peripheral Nerve Pain Management
University of Texas at Austin
NCT07160049
Opioid-Free Orthopaedic Surgery
OrthoCarolina Research Institute
NCT04176783
The Alabama NSAIDs Patient Safety Survey, Phase II: Reducing Disparities in Risk Awareness and Communication
University of Alabama at Birmingham
NCT01352832
Tramadol Versus Placebo in the Management of Postoperative Pain Following Bunionectomy
Avenue Therapeutics
NCT03290378
Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section
Pacira Pharmaceuticals
NCT03853694
Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty
Pacira Pharmaceuticals
NCT05139030
Post-partum Non-pharmacologic Pain Management
Wright State University
NCT03903172
Effectiveness of External Vibration for Pain Relief During Intravenous Access in Adult Patients
Kyle Stein
NCT03619135
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation
Ashley Turner, MD
NCT03868787
Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
University of California, Irvine
NCT02276495
PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery
Pacira Pharmaceuticals
NCT02985762
Erector Spinae Regional Anesthesia for Pain Control
The University of Texas Health Science Center at San Antonio
NCT05794828
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
The University of Texas Health Science Center, Houston
NCT04750525
Combined Peripheral (BreEStim) and Central Electrical Stimulation (tDCS) for Neuropathic Pain Management - Spinal Cord Injury
The University of Texas Health Science Center, Houston
NCT03302793
BreEStim and tDCS for Neuropathic Pain Management - Healthy Subjects
The University of Texas Health Science Center, Houston
NCT03302780
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 3 |
| Phase 3 | 6 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Pain Management Trial Landscape
ClinicalTrials.gov lists 32 US studies indexed under Pain Management, and 13 of those are currently open to recruitment — roughly 41% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Pain Management shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Pain Management is led by Pacira Pharmaceuticals with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 32 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Pain Management?
PlainTrial tracks 32 US clinical trials for Pain Management, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Pain Management?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.