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NCT06429501 · ClinicalTrials.gov registry record · Phase 2
Local Anesthesia for Facial Fractures
A Phase 2 study of Pain Management, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06429501: Recruiting Phase 2 study of Pain Management, sponsored by Washington University School of Medicine.
NCT06429501 is a Phase 2 study of Pain Management that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 70 participants, below the 153-participant average among 31 other Pain Management trials with a reported enrollment target (54% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06429501, a Phase 2 study of Pain Management, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics. Patients with operative facial fractures are randomized to receive either bupivacaine or saline injections prior to the anesthesia emergence.
Primary Outcome
To evaluate the impact of a perioperative bupivacaine nerve block on PACU opioid use in patients undergoing operative fixation of facial fractures compared to placebo nerve block assessment of the amount of opioids that patients receive in PACU in morphine milligram equivalents (MMEs) will be calculated.
Conditions Studied
Interventions
- DRUG Saline
- DRUG Bupivacaine/Epinephrine
Study Locations (1)
Missouri
- Washington University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2024-04-02 |
| Est. Completion | 2027-07-01 |
| Phase | Phase 2 |
What NCT06429501 shows while recruiting
NCT06429501 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 153-participant average among 31 other Pain Management trials with a reported enrollment target (54% lower).
The record links to 1 condition, with Pain Management appearing as the primary indexed condition, and to 2 interventions - of which Saline is the first listed.
NCT06429501 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT06429501 about?
NCT06429501 is a clinical study titled "Local Anesthesia for Facial Fractures". The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics. Patients with operative facial fractures are randomized to receive either bupivacaine or saline injections prior to the anesthesia emergence.
What is the current status of trial NCT06429501?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2024-04-02. Estimated completion is 2027-07-01.
What conditions does trial NCT06429501 study?
This clinical trial studies the following conditions: Pain Management.
What interventions are being tested in trial NCT06429501?
The interventions under investigation include: Saline (DRUG), Bupivacaine/Epinephrine (DRUG).
Who is sponsoring clinical trial NCT06429501?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06429501 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain Management
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06429501's enrollment target sits among peer trials
70 21st of 31 higher than 11 of 31 other Pain Management trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain Management trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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