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NCT07158476 · ClinicalTrials.gov registry record · Phase 4
Efficacy of Methylprednisolone for Pain Control After ACL Repair
A Phase 4 study of Pain Management and ACL Surgery, sponsored by St. Louis University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT07158476 is a Phase 4 study of Pain Management and ACL Surgery that is actively recruiting participants, run by St. Louis University. The registered enrollment target is 90 participants, below the 152-participant average among 31 other Pain Management trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07158476, a Phase 4 study of Pain Management and ACL Surgery, is actively recruiting participants, sponsored by St. Louis University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.
Conditions Studied
Interventions
- DRUG Meloxicam 15 mg
- DRUG Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- DRUG Gabapentin 300 mg
- DRUG Hydrocodone 5Mg/Acetaminophen 325Mg Tab
- DRUG Ketorolac 10 Mg Oral Tablet
Study Locations (1)
Missouri
- Saint Louis University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2025-10-21 |
| Est. Completion | 2031-09 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07158476
The ClinicalTrials.gov registry entry for NCT07158476 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 152-participant average among 31 other Pain Management trials with a reported enrollment target (41% lower). The listed sponsor is St. Louis University, which has 107 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Pain Management appearing as the primary indexed condition, and to 5 interventions - of which Meloxicam 15 mg is the first listed.
NCT07158476 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT07158476 about?
NCT07158476 is a clinical study titled "Efficacy of Methylprednisolone for Pain Control After ACL Repair". Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repa...
What is the current status of trial NCT07158476?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 90 participants. The study started on 2025-10-21. Estimated completion is 2031-09.
What conditions does trial NCT07158476 study?
This clinical trial studies the following conditions: Pain Management, ACL Surgery.
What interventions are being tested in trial NCT07158476?
The interventions under investigation include: Meloxicam 15 mg (DRUG), Medrol 4 MG Oral Tablet Includes Medrol Dosepak (DRUG), Gabapentin 300 mg (DRUG), Hydrocodone 5Mg/Acetaminophen 325Mg Tab (DRUG), Ketorolac 10 Mg Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT07158476?
This trial is sponsored by St. Louis University, which has 107 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07158476 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.