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NCT07158476 · ClinicalTrials.gov registry record · Phase 4
Efficacy of Methylprednisolone for Pain Control After ACL Repair
A Phase 4 study of Pain Management and ACL Surgery, sponsored by St. Louis University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 90
- Enrollment target
- 1
- Study location
NCT07158476: Recruiting Phase 4 study of Pain Management and ACL Surgery, sponsored by St. Louis University.
NCT07158476 is a Phase 4 study of Pain Management and ACL Surgery that is actively recruiting participants, run by St. Louis University. The registered enrollment target is 90 participants, below the 152-participant average among 31 other Pain Management trials with a reported enrollment target (41% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07158476, a Phase 4 study of Pain Management and ACL Surgery, is actively recruiting participants, sponsored by St. Louis University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 90 participants
- Enrollment target
- 1
- Study location
Study Summary
Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine if this results in decreased postoperative pain and opioid use without increasing complications.
Primary Outcome
Zero is equivalent to no pain and 10 indicates the worst possible pain
Conditions Studied
Interventions
- DRUG Meloxicam 15 mg
- DRUG Medrol 4 MG Oral Tablet Includes Medrol Dosepak
- DRUG Gabapentin 300 mg
- DRUG Hydrocodone 5Mg/Acetaminophen 325Mg Tab
- DRUG Ketorolac 10 Mg Oral Tablet
Study Locations (1)
Missouri
- Saint Louis University - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2025-10-21 |
| Est. Completion | 2031-09 |
| Phase | Phase 4 |
What NCT07158476 shows while recruiting
NCT07158476 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 152-participant average among 31 other Pain Management trials with a reported enrollment target (41% lower).
The record links to 2 conditions, with Pain Management appearing as the primary indexed condition, and to 5 interventions - of which Meloxicam 15 mg is the first listed.
NCT07158476 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT07158476 about?
NCT07158476 is a clinical study titled "Efficacy of Methylprednisolone for Pain Control After ACL Repair". Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repa...
What is the current status of trial NCT07158476?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 90 participants. The study started on 2025-10-21. Estimated completion is 2031-09.
What conditions does trial NCT07158476 study?
This clinical trial studies the following conditions: Pain Management, ACL Surgery.
What interventions are being tested in trial NCT07158476?
The interventions under investigation include: Meloxicam 15 mg (DRUG), Medrol 4 MG Oral Tablet Includes Medrol Dosepak (DRUG), Gabapentin 300 mg (DRUG), Hydrocodone 5Mg/Acetaminophen 325Mg Tab (DRUG), Ketorolac 10 Mg Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT07158476?
This trial is sponsored by St. Louis University, which has 107 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07158476 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain Management
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07158476's enrollment target sits among peer trials
90 19th of 31 higher than 13 of 31 other Pain Management trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain Management trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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