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2026 data Public-data reference. official source

Obesity, Morbid

Open-data reference.

20 US clinical trials · 8 currently recruiting

Active & Recent Trials

RECRUITING NA 250 participants

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

Rush University Medical Center

NCT05918575

RECRUITING NA 100 participants

Trans-nasal Endoscopy for Bariatric Patients

Christopher C. Thompson, MD, MSc

NCT06200961

RECRUITING 60 participants

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Mayo Clinic

NCT04232566

RECRUITING NA 60 participants

Time-restricted Eating Among Pregnant Females With Severe Obesity

University of Illinois at Chicago

NCT06477120

RECRUITING Early Phase 1 30 participants

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

University of Chicago

NCT06171152

RECRUITING 30 participants

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

Christopher C. Thompson, MD, MSc

NCT05711758

RECRUITING NA 30 participants

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

Mayo Clinic

NCT03868592

RECRUITING NA 10 participants

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Oregon Health and Science University

NCT04326192

ACTIVE NOT RECRUITING NA 560 participants

Rural Engagement in TelemedTeam for Options in Obesity Treatment Solutions

University of Kansas Medical Center

NCT05710510

ACTIVE NOT RECRUITING 500 participants

Biological Sample Repository for Gastrointestinal Disorders

Pichamol Jirapinyo, MD, MPH

NCT05874726

ACTIVE NOT RECRUITING NA 80 participants

Positive Psychology Intervention for Patients Post-bariatric Surgery and Their Partners

Larissa McGarrity, Ph.D.

NCT05958615

ACTIVE NOT RECRUITING Phase 4 60 participants

Multimodal Analgesia Effect on Post Surgical Patient

University of California, Davis

NCT04240626

ACTIVE NOT RECRUITING NA 53 participants

Clinical Investigation of the da Vinci Surgical System

Intuitive Surgical

NCT05682742

ACTIVE NOT RECRUITING NA 20 participants

Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity

Brigham and Women's Hospital

NCT05713071

ACTIVE NOT RECRUITING NA 6 participants

Responsive Neurostimulation For Loss Of Control Eating

University of Pennsylvania

NCT03868670

COMPLETED 36 participants

Bariatric Surgery on Short Term Weight Loss- Related Changes in Gait

University of Florida

NCT01447316

COMPLETED Phase 2 34 participants

Topiramate in Adolescents With Severe Obesity

University of Minnesota

NCT01859013

COMPLETED 31 participants

Contributing Factors in the Pathobiology of Airway Remodeling in Obesity

Duke University

NCT03115632

COMPLETED Phase 1 7 participants

PET Imaging and Bariatric Surgery

Vanderbilt University Medical Center

NCT00801827

COMPLETED NA 6 participants

Efficacy of Vitamin D Supplementation in Obese Children

Columbia University

NCT02956408

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Obesity, Morbid Trial Landscape

ClinicalTrials.gov lists 20 US studies indexed under Obesity, Morbid, and 8 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Obesity, Morbid shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Obesity, Morbid is led by Christopher C. Thompson, MD, MSc with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Obesity, Morbid?

PlainTrial tracks 20 US clinical trials for Obesity, Morbid, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Obesity, Morbid?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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