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ClinicalTrials.gov 8 recruiting now early-phase tilt

Obesity, Morbid: early-phase trial registry

8 of 20 indexed Obesity, Morbid trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 8 currently recruiting · #848 of 28,707 conditions by registered trial count

Obesity, Morbid: 20 US clinical trials tracked, 8 recruiting.

Obesity, Morbid is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Christopher C. Thompson, MD, MSc, running 2 of these trials.

Enrollment posture brief

Registry condition obesity-morbid

OPEN 8 | RECR 40% | LATE 1 | EARLY 3 | RANK #848 | SPON 2

Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)

Advanced or Metastatic Solid55%ALS50%Obesity, Morbid (this)40%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Obesity, Morbid

Obesity, Morbid lists 8 open slots (40% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Obesity, Morbid on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Obesity, Morbid recruits in line with its size-band peers.

    8 of 20 indexed trials (40%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Obesity, Morbid trials is spread across many organizations.

    Christopher C. Thompson, MD, MSc accounts for 2 of 20 trials (10%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Most Obesity, Morbid trials plan to enrol fewer than 100 people.

    Median target enrolment is 36 among the 20 trials that report a genuine target (sentinel values excluded). 16 of those (80%) plan for fewer than 100 participants.

  4. Obesity, Morbid research is mostly interventional.

    15 interventional and 5 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 21Phase 41

Open and recent trials

20 total, page 1 of 1

RECRUITING NA 250 participants

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

Rush University Medical Center

NCT05918575

RECRUITING NA 100 participants

Trans-nasal Endoscopy for Bariatric Patients

Christopher C. Thompson, MD, MSc

NCT06200961

RECRUITING 60 participants

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

Mayo Clinic

NCT04232566

RECRUITING NA 60 participants

Time-restricted Eating Among Pregnant Females With Severe Obesity

University of Illinois at Chicago

NCT06477120

RECRUITING Early Phase 1 30 participants

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

University of Chicago

NCT06171152

RECRUITING 30 participants

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

Christopher C. Thompson, MD, MSc

NCT05711758

RECRUITING NA 30 participants

Long-term, Substantial Weight Loss and Insulin Regulation of Lipolysis

Mayo Clinic

NCT03868592

RECRUITING NA 10 participants

Brown Adipose Tissue Activation by Spinal Cord Stimulation

Oregon Health and Science University

NCT04326192

ACTIVE NOT RECRUITING NA 560 participants

Rural Engagement in TelemedTeam for Options in Obesity Treatment Solutions

University of Kansas Medical Center

NCT05710510

ACTIVE NOT RECRUITING 500 participants

Biological Sample Repository for Gastrointestinal Disorders

Pichamol Jirapinyo, MD, MPH

NCT05874726

ACTIVE NOT RECRUITING NA 80 participants

Positive Psychology Intervention for Patients Post-bariatric Surgery and Their Partners

Larissa McGarrity, Ph.D.

NCT05958615

ACTIVE NOT RECRUITING Phase 4 60 participants

Multimodal Analgesia Effect on Post Surgical Patient

University of California, Davis

NCT04240626

ACTIVE NOT RECRUITING NA 53 participants

Clinical Investigation of the da Vinci Surgical System

Intuitive Surgical

NCT05682742

ACTIVE NOT RECRUITING NA 20 participants

Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity

Brigham and Women's Hospital

NCT05713071

ACTIVE NOT RECRUITING NA 6 participants

Responsive Neurostimulation For Loss Of Control Eating

University of Pennsylvania

NCT03868670

COMPLETED 36 participants

Bariatric Surgery on Short Term Weight Loss- Related Changes in Gait

University of Florida

NCT01447316

COMPLETED Phase 2 34 participants

Topiramate in Adolescents With Severe Obesity

University of Minnesota

NCT01859013

COMPLETED 31 participants

Contributing Factors in the Pathobiology of Airway Remodeling in Obesity

Duke University

NCT03115632

COMPLETED Phase 1 7 participants

PET Imaging and Bariatric Surgery

Vanderbilt University Medical Center

NCT00801827

COMPLETED NA 6 participants

Efficacy of Vitamin D Supplementation in Obese Children

Columbia University

NCT02956408

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 1
Phase 4 1

Named interventions

Most-linked intervention names on Obesity, Morbid records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

F-18 (fallypride) Drug
1 trials
Subject outcomes following bariatric surgery Other
1 trials
Tissue Sample Collection Diagnostic test
1 trials
Urine Collection Diagnostic test
1 trials
Hycet 7.5Mg-325Mg/15Ml Solution Drug
1 trials
Oxycodone Hydrochloride Drug
1 trials
Marcaine Injectable Product Drug
1 trials
Dilaudid Injectable Product Drug
1 trials

US sites by state

Facility locations filed on Obesity, Morbid trials. A trial with sites in several states counts in each.

Massachusetts 4 trials
Illinois 3 trials
Minnesota 2 trials
Florida 2 trials
California 2 trials
Wisconsin 1 trials
Utah 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Obesity, Morbid page

20 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Obesity, Morbid condition card totals 20 registered trials; most-linked intervention F-18 (fallypride); top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.