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NCT05918575 · ClinicalTrials.gov registry record · NA
Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients
A NA study of Obesity, Morbid and Extubation Failure, sponsored by Rush University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 250
- Enrollment target
- 5
- Study locations
NCT05918575: Recruiting NA study of Obesity, Morbid and Extubation Failure, sponsored by Rush University Medical Center.
NCT05918575 is a NA study of Obesity, Morbid and Extubation Failure that is actively recruiting participants, run by Rush University Medical Center. The registered enrollment target is 250 participants, above the 90-participant average among 19 other Obesity, Morbid trials with a reported enrollment target (178% higher). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05918575, a NA study of Obesity, Morbid and Extubation Failure, is actively recruiting participants, sponsored by Rush University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 250 participants
- Enrollment target
- 5
- Study locations
Study Summary
Around 20% of the obese patients with higher body mass index (BMI) who are taken off the breathing tube and breathing machine (ventilator) end up needing it back to support breathing. The re-application of breathing tube is associated with poor outcomes, including high risk of pneumonia, longer hospital stays, and death. The purpose of this study is to assess if prophylactic use of noninvasive breathing support after removing the breathing tube lowers the chance of needing the breathing tube again.
Primary Outcome
Rescue respiratory support is defined as reintubation, use of rescue NIV or HFNC use
Conditions Studied
Interventions
- DEVICE Noninvasive ventilation alternating with high flow nasal cannula
- DEVICE High flow nasal cannula
Study Locations (5)
Illinois
- Rush University Medical Center - Chicago
- Central DuPage Hospital - Winfield
Texas
- McGovern Medical School, The University of Texas Health Science Center - Houston
Wisconsin
- Medical College of Wisconsin - Milwaukee
Jalisco
- Hospital Civil Fray Antonio Alcalde - Guadalajara
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2023-07-10 |
| Est. Completion | 2026-12-01 |
| Phase | NA |
What NCT05918575 shows while recruiting
NCT05918575 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, above the 90-participant average among 19 other Obesity, Morbid trials with a reported enrollment target (178% higher).
The record links to 2 conditions, with Obesity, Morbid appearing as the primary indexed condition, and to 2 interventions - of which Noninvasive ventilation alternating with high flow nasal cannula is the first listed.
NCT05918575 lists 5 locations in 4 states (Illinois, Texas, Wisconsin).
Frequently Asked Questions
What is clinical trial NCT05918575 about?
NCT05918575 is a clinical study titled "Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients". Around 20% of the obese patients with higher body mass index (BMI) who are taken off the breathing tube and breathing machine (ventilator) end up needing it back to support breathing. The re-application of breathing tube is associated with poor outcomes, including high risk of pneumonia, longer hosp...
What is the current status of trial NCT05918575?
This trial is currently recruiting. It is a NA study. The enrollment target is 250 participants. The study started on 2023-07-10. Estimated completion is 2026-12-01.
What conditions does trial NCT05918575 study?
This clinical trial studies the following conditions: Obesity, Morbid, Extubation Failure.
What interventions are being tested in trial NCT05918575?
The interventions under investigation include: Noninvasive ventilation alternating with high flow nasal cannula (DEVICE), High flow nasal cannula (DEVICE).
Who is sponsoring clinical trial NCT05918575?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05918575 being conducted?
This trial has 5 study locations across Illinois, Texas, Wisconsin, Jalisco. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05918575's enrollment target sits among peer trials
250 3rd of 19 higher than 17 of 19 other Obesity, Morbid trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity, Morbid trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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