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ClinicalTrials.gov 8 recruiting now official registry

Neurodegenerative Diseases clinical trials

Every US clinical trial registered for Neurodegenerative Diseases — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

13 US clinical trials · 8 currently recruiting

The research picture

Neurodegenerative Diseases has 13 registered US clinical trials, 8 of them open to new participants right now — about 62% of the total.

8
recruiting participants now
62%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
1
top sponsor: Elizabeth K Rhodus

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING NA 500 participants

Neurologic Stem Cell Treatment Study

MD Stem Cells

NCT02795052

RECRUITING 200 participants

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Boston Children's Hospital

NCT05354622

RECRUITING Phase 2 100 participants

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

University of Arizona

NCT04838301

RECRUITING Phase 4 75 participants

Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

Vanderbilt University Medical Center

NCT05357612

RECRUITING NA 60 participants

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

University of Texas at Austin

NCT05741853

RECRUITING 40 participants

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Mclean Hospital

NCT05245903

RECRUITING NA 30 participants

Home Exercise for Individuals with Neurodegenerative Disease

Hugo W. Moser Research Institute at Kennedy Krieger

NCT05443906

ACTIVE NOT RECRUITING NA 20,000 participants

Mobile Parkinson Observatory for Worldwide, Evidence-based Research (mPower)

Sage Bionetworks

NCT02696603

ACTIVE NOT RECRUITING Phase 3 1,175 participants

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

Eli Lilly and Company

NCT05738486

ACTIVE NOT RECRUITING Phase 2 110 participants

AMX0035 and Progressive Supranuclear Palsy

Amylyx Pharmaceuticals

NCT06122662

COMPLETED NA 80 participants

Harmony at Home: A Pilot Telehealth Program for Rural ADRD Caregivers

Elizabeth K Rhodus

NCT05202223

COMPLETED NA 38 participants

Assessing a Novel Virtual Environment That Assists With Activities of Daily Living

mandy

NCT05418296

Phase Distribution

PhaseTrial count
Phase 2 2
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neurodegenerative Diseases Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Neurodegenerative Diseases, and 8 of those are currently open to recruitment — roughly 62% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Neurodegenerative Diseases shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Neurodegenerative Diseases is led by Elizabeth K Rhodus with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neurodegenerative Diseases?

PlainTrial tracks 13 US clinical trials for Neurodegenerative Diseases, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neurodegenerative Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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