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ClinicalTrials.gov 16 recruiting now official registry

Neck Pain clinical trials

Every US clinical trial registered for Neck Pain — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

32 US clinical trials · 16 currently recruiting

The research picture

Neck Pain has 32 registered US clinical trials, 16 of them open to new participants right now — about 50% of the total.

16
recruiting participants now
50%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: San Diego State University

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING NA 17,587 participants

Stratified Targeted Engagement From Primary Care to Physical Therapy (STEPPT)

San Diego State University

NCT07290361

RECRUITING 10,500 participants

The Spine Phenome Project

Ohio State University

NCT05776771

RECRUITING 5,000 participants

Evaluation of the Effects of a Rehabilitation Program in Individuals with Spine Pain

SpineZone Medical Fitness

NCT04081896

RECRUITING NA 460 participants

Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain

Rush University Medical Center

NCT06044649

RECRUITING 400 participants

Wearable Spine Health System for Military Readiness

Ohio State University

NCT05944354

RECRUITING NA 376 participants

Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain

University of Minnesota

NCT06696352

RECRUITING Phase 3 375 participants

CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial

Stanford University

NCT06027099

RECRUITING Phase 3 157 participants

Safety and Efficacy of Oral Cannabis in Chronic Spine Pain

University of Colorado, Denver

NCT05052541

RECRUITING NA 120 participants

Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS)

Henry M. Jackson Foundation for the Advancement of Military Medicine

NCT06214949

RECRUITING NA 60 participants

Normalizing Cervical Intersegmental Kinematics With Spinal Manipulative Therapy

University of Minnesota

NCT06312696

RECRUITING NA 53 participants

Response to Massage in Neck Pain

University of Florida

NCT06224829

RECRUITING NA 50 participants

CEM-Plate and CEM-Cage First-In-Human Use Efficacy Study

ReVivo Medical

NCT04883411

RECRUITING NA 48 participants

Chronic Non-Specific Neck Pain Treated With Tai Chi and Chiropractic Care

Harvard University Faculty of Medicine

NCT05726331

RECRUITING NA 40 participants

Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain

University of Pittsburgh

NCT06616272

RECRUITING NA 40 participants

A Novel Device for Neck Pain in Active-duty Military Personnel With Forward Head Posture.

Kessler Foundation

NCT05433025

RECRUITING NA 30 participants

The Effect of Osteopathic Treatment on Craniocervico-Mandibular Dysfunction

Edward Via Virginia College of Osteopathic Medicine

NCT06471426

ACTIVE NOT RECRUITING NA 198 participants

Development of STEPPT

San Diego State University

NCT06835439

ACTIVE NOT RECRUITING 60 participants

Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes

Johns Hopkins University

NCT05450679

ACTIVE NOT RECRUITING NA 30 participants

How Dry Needling at the Neck Affects Shoulder Movement, Strength, Pain, and Shoulder Circulation

Texas Woman's University

NCT06705634

ACTIVE NOT RECRUITING NA 28 participants

Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance

Mayo Clinic

NCT06275074

COMPLETED NA 395 participants

Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated

VA Office of Research and Development

NCT03100539

COMPLETED NA 316 participants

PNE Effectiveness Cluster Trial

University of Utah

NCT03168165

COMPLETED Phase 1 140 participants

Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization

Franklin Pierce University

NCT00504686

COMPLETED NA 120 participants

Study of Opioid Use After Lumbar and Cervical Spine Surgery

Brooke Army Medical Center

NCT02674711

COMPLETED NA 64 participants

Short-Term Effects of Combined Manual Therapy to the Cervical and Thoracic Spine

Masefield and Cavallaro Physical Therapy

NCT01318720

COMPLETED Phase 1 62 participants

The Effectiveness of a Mechanical Manual Therapy Device in the Treatment of Neck Pain

University of Florida

NCT01168986

COMPLETED NA 45 participants

Cervical Spine Manipulation Affects on Balance and Proprioception

University of Nevada, Las Vegas

NCT01745705

COMPLETED NA 45 participants

Dry Needling vs Dry Needling With ES in Patients With Neck/Shoulder Pain

Kindyle Brennan

NCT03638388

COMPLETED NA 40 participants

Validation of the Cervicothoracic Differentiation Test

University of Hartford

NCT06287242

COMPLETED NA 33 participants

Comparing Sports Bra Design in Full Busted Women

University of Houston

NCT05456594

COMPLETED NA 17 participants

Preliminary Neck Classification Study

St. Ambrose University

NCT02850549

COMPLETED NA 8 participants

Microbreaks in the OR to Mitigate High Physical and Mental Demands

Mayo Clinic

NCT02565394

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neck Pain Trial Landscape

ClinicalTrials.gov lists 32 US studies indexed under Neck Pain, and 16 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Neck Pain shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Neck Pain is led by San Diego State University with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 32 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neck Pain?

PlainTrial tracks 32 US clinical trials for Neck Pain, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neck Pain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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