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NCT05450679 · ClinicalTrials.gov registry record
Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes
A clinical trial of Chronic Pain and Neck Pain, sponsored by Johns Hopkins University.
- Active
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT05450679: Active study of Chronic Pain and Neck Pain, sponsored by Johns Hopkins University.
NCT05450679 is a study of Chronic Pain and Neck Pain that is active but no longer recruiting, run by Johns Hopkins University. The registered enrollment target is 60 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05450679, a study of Chronic Pain and Neck Pain, is active but no longer recruiting, sponsored by Johns Hopkins University.
- ACTIVE NOT RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or duration of analgesia. The investigators propose a straightforward grading scale based on visual and tactile information readily available during RFA procedures as part of routine practice (per radiofrequency electrode: 0 = no twitches palpated or observed; 1 = twitches palpated but not observed; 2 = twitches palpated and observed at 1-2 levels; 3= twitches palpated and observed at \>2 levels). If a higher weighted score (total score divided by number of radiofrequency lesion sites) correlates with a greater likelihood of treatment success, or magnitude or duration of analgesia following cervical RFA, cervical paraspinal muscle twitching may serve as a readily obtainable prognostic factor (marker) for effectiveness.
Primary Outcome
Definition of success: a \>/= 2-point decrease in average neck pain (measured over the past week) coupled with a score of \>/= 5/7 on a patient global impression of change (PGIC) scale where 1= "no change or worsened symptoms", 5= "moderately better, a slight but noticeable change", and 7= "a great deal better."
Conditions Studied
Interventions
- PROCEDURE Cervical Radiofrequency Ablation (RFA)
Study Locations (1)
Maryland
- Johns Hopkins Hospital - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2022-09-13 |
| Est. Completion | 2027-08-01 |
What the registry record for NCT05450679 still lists
NCT05450679 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (92% lower).
The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 1 intervention - of which Cervical Radiofrequency Ablation (RFA) is the first listed.
NCT05450679 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05450679 about?
NCT05450679 is a clinical study titled "Cervical Paraspinal Muscle Twitching and Cervical Facet Radiofrequency Ablation Outcomes". The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or duration of analgesia. The investigators propose a straightforward gradin...
What is the current status of trial NCT05450679?
This trial is currently active not recruiting. The enrollment target is 60 participants. The study started on 2022-09-13. Estimated completion is 2027-08-01.
What conditions does trial NCT05450679 study?
This clinical trial studies the following conditions: Chronic Pain, Neck Pain, Cervical Facet Joint Pain.
What interventions are being tested in trial NCT05450679?
The interventions under investigation include: Cervical Radiofrequency Ablation (RFA) (PROCEDURE).
Who is sponsoring clinical trial NCT05450679?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05450679 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05450679's enrollment target sits among peer trials
60 176th of 301 higher than 112 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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