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ClinicalTrials.gov 5 recruiting now early-phase tilt small index

Myeloproliferative Disorders: early-phase trial registry

5 of 9 indexed Myeloproliferative Disorders trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 5 currently recruiting · #1,916 of 28,707 conditions by registered trial count

Myeloproliferative Disorders: 9 US clinical trials tracked, 5 recruiting.

Myeloproliferative Disorders is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 2 of these trials.

Enrollment posture brief

Registry condition myeloproliferative-disorders

OPEN 5 | RECR 56% | LATE 1 | EARLY 7 | RANK #1916 | SPON 2

Nearest open-share peer: Advanced Colorectal Cancer (56% recruiting · 9 trials)

Myeloproliferative Disor (th…56%Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near Myeloproliferative Disorders

Myeloproliferative Disorders lists 5 open slots (56% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Myeloproliferative Disorders on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Myeloproliferative Disorders is recruiting above its size-band peers.

    5 of 9 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Myeloproliferative Disorders research.

    National Heart, Lung, and Blood Institute (NHLBI) accounts for 2 of 9 trials (22.2%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most Myeloproliferative Disorders trials plan to enrol fewer than 100 people.

    Median target enrolment is 32 among the 9 trials that report a genuine target (sentinel values excluded). 7 of those (77.8%) plan for fewer than 100 participants.

  4. Myeloproliferative Disorders research is mostly interventional.

    9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 24Phase 31

Open and recent trials

9 total, page 1 of 1

RECRUITING Phase 1 60 participants

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Stanford University

NCT05088356

RECRUITING Phase 2 56 participants

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

University of Alabama at Birmingham

NCT06265584

RECRUITING NA 30 participants

I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

Massachusetts General Hospital

NCT05842603

RECRUITING Phase 2 29 participants

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

University of Alabama at Birmingham

NCT06315309

RECRUITING Phase 1 15 participants

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

Dana-Farber Cancer Institute

NCT06138587

ACTIVE NOT RECRUITING Phase 3 313 participants

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

Celgene

NCT04717414

ACTIVE NOT RECRUITING Phase 1 32 participants

Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05823571

COMPLETED Phase 2 202 participants

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00003838

COMPLETED Phase 2 14 participants

Experimental Bone Marrow Transplant Protocol

National Heart, Lung, and Blood Institute (NHLBI)

NCT00061581

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 4
Phase 3 1

Named interventions

Most-linked intervention names on Myeloproliferative Disorders records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Isolex 300i Stem Cell Selection Device
1 trials
T-cell replete PBPC allograft Procedure
1 trials
Cytokine Induced Memory-like Natural Killer Cells Biological
1 trials
ACE-536 Drug
1 trials
Cardiac Lifestyle Program Behavioral
1 trials
Cyclosporine Drug
1 trials
Methotrexate Drug
1 trials
ATG Combined with Tacrolimus and Mini Methotrexate Drug
1 trials

US sites by state

Facility locations filed on Myeloproliferative Disorders trials. A trial with sites in several states counts in each.

Maryland 3 trials
Massachusetts 2 trials
California 2 trials
Alabama 2 trials
Utah 1 trials
Texas 1 trials
Tennessee 1 trials
Pennsylvania 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Myeloproliferative Disorders page

9 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Myeloproliferative Disorders condition card totals 9 registered trials; most-linked intervention Isolex 300i Stem Cell Selection; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.