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Myasthenia Gravis
Open-data reference.
33 US clinical trials · 20 currently recruiting
Active & Recent Trials
Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment
ZS Associates
NCT06866483
The EXPLORE MG Registry for Myasthenia Gravis
Yale University
NCT03792659
A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa
argenx
NCT06298565
Vitaccess Real MG Registry
Vitaccess
NCT06064461
A Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding.
argenx
NCT06299748
Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)
University of California, San Francis
NCT06940323
A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis
Janssen Research & Development
NCT04951622
The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis
Ad scientiam
NCT05564936
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
NCT06220201
Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis
Janssen Research & Development
NCT07217587
A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis
ImmunAbs
NCT07250750
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis
NMD Pharma A/S
NCT06414954
ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis
argenx
NCT07294170
ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod
argenx
NCT07284420
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis
Kyverna Therapeutics
NCT06193889
Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis
COUR Pharmaceutical Development Company
NCT06106672
Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease
University of Missouri-Columbia
NCT07478172
A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases
Arcellx
NCT06626919
Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis
HealthPartners Institute
NCT06491238
A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis
Janssen Research & Development
NCT05265273
Exploring Outcomes and Characteristics of Myasthenia Gravis 2
Yale University
NCT06002945
Myasthenia Gravis Inebilizumab Trial
Amgen
NCT04524273
A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis
argenx
NCT06298552
SP Thoracic IDE Study
Intuitive Surgical
NCT05150210
Expediting Myasthenia Gravis (MG) Diagnostic Evaluation: A Novel, Proof-of-Concept for Undiagnosed, Symptomatic Patients That Uses Social Media Targeting and Self-Assessment
ZS Associates
NCT06381284
Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy
University of Alabama at Birmingham
NCT00294658
Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders
Beth Israel Deaconess Medical Center
NCT02118805
BeatMG: Phase II Trial of Rituximab In Myasthenia Gravis
Yale University
NCT02110706
A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness
argenx
NCT02965573
Acupuncture in Myasthenia Gravis (AcuMG)
HealthPartners Institute
NCT05230082
Clinical Trial to Improve the Magnetic Levator Prosthesis
Massachusetts Eye and Ear Infirmary
NCT03818204
A Study of RVT-1401 in Myasthenia Gravis (MG) Patients
Immunovant Sciences
NCT03863080
Yogic Breathing Exercise for People With Amyotrophic Lateral Sclerosis
University of Alabama at Birmingham
NCT05979688
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 4 |
| Phase 2 | 7 |
| Phase 3 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Myasthenia Gravis Trial Landscape
ClinicalTrials.gov lists 33 US studies indexed under Myasthenia Gravis, and 20 of those are currently open to recruitment — roughly 61% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Myasthenia Gravis shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Myasthenia Gravis is led by argenx with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 33 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Myasthenia Gravis?
PlainTrial tracks 33 US clinical trials for Myasthenia Gravis, of which 20 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Myasthenia Gravis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.