Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Myasthenia Gravis

Open-data reference.

33 US clinical trials · 20 currently recruiting

Active & Recent Trials

RECRUITING 1,000 participants

Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment

ZS Associates

NCT06866483

RECRUITING 800 participants

The EXPLORE MG Registry for Myasthenia Gravis

Yale University

NCT03792659

RECRUITING 680 participants

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

argenx

NCT06298565

RECRUITING 600 participants

Vitaccess Real MG Registry

Vitaccess

NCT06064461

RECRUITING 279 participants

A Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding.

argenx

NCT06299748

RECRUITING 250 participants

Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)

University of California, San Francis

NCT06940323

RECRUITING Phase 3 199 participants

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

Janssen Research & Development

NCT04951622

RECRUITING NA 144 participants

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

Ad scientiam

NCT05564936

RECRUITING Phase 1 120 participants

A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

NCT06220201

RECRUITING Phase 3 115 participants

Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis

Janssen Research & Development

NCT07217587

RECRUITING Phase 1 96 participants

A Phase 1b/2 Study of IM-101 in Adult Participants With Generalized Myasthenia Gravis and Ocular Myasthenia Gravis

ImmunAbs

NCT07250750

RECRUITING Phase 2 84 participants

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

NMD Pharma A/S

NCT06414954

RECRUITING 70 participants

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

argenx

NCT07294170

RECRUITING Phase 2 70 participants

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

argenx

NCT07284420

RECRUITING Phase 2 66 participants

KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis

Kyverna Therapeutics

NCT06193889

RECRUITING Phase 1 54 participants

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

COUR Pharmaceutical Development Company

NCT06106672

RECRUITING NA 50 participants

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

University of Missouri-Columbia

NCT07478172

RECRUITING Phase 1 30 participants

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

Arcellx

NCT06626919

RECRUITING NA 20 participants

Light vs. Moderate Intensity Exercise in Individuals With Myasthenia Gravis

HealthPartners Institute

NCT06491238

RECRUITING Phase 2 12 participants

A Study of Nipocalimab in Children Aged 2 to Less Than 18 Years With Generalized Myasthenia Gravis

Janssen Research & Development

NCT05265273

ACTIVE NOT RECRUITING 400 participants

Exploring Outcomes and Characteristics of Myasthenia Gravis 2

Yale University

NCT06002945

ACTIVE NOT RECRUITING Phase 3 238 participants

Myasthenia Gravis Inebilizumab Trial

Amgen

NCT04524273

ACTIVE NOT RECRUITING Phase 3 119 participants

A Phase 3 Study to Evaluate the Efficacy and Safety of Efgartigimod IV in Patients With Acetylcholine Receptor Binding Antibody Seronegative Generalized Myasthenia Gravis

argenx

NCT06298552

ACTIVE NOT RECRUITING NA 32 participants

SP Thoracic IDE Study

Intuitive Surgical

NCT05150210

COMPLETED 215 participants

Expediting Myasthenia Gravis (MG) Diagnostic Evaluation: A Novel, Proof-of-Concept for Undiagnosed, Symptomatic Patients That Uses Social Media Targeting and Self-Assessment

ZS Associates

NCT06381284

COMPLETED Phase 3 126 participants

Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy

University of Alabama at Birmingham

NCT00294658

COMPLETED 100 participants

Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders

Beth Israel Deaconess Medical Center

NCT02118805

COMPLETED Phase 2 52 participants

BeatMG: Phase II Trial of Rituximab In Myasthenia Gravis

Yale University

NCT02110706

COMPLETED Phase 2 24 participants

A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

argenx

NCT02965573

COMPLETED NA 24 participants

Acupuncture in Myasthenia Gravis (AcuMG)

HealthPartners Institute

NCT05230082

COMPLETED NA 19 participants

Clinical Trial to Improve the Magnetic Levator Prosthesis

Massachusetts Eye and Ear Infirmary

NCT03818204

COMPLETED Phase 2 17 participants

A Study of RVT-1401 in Myasthenia Gravis (MG) Patients

Immunovant Sciences

NCT03863080

COMPLETED NA 13 participants

Yogic Breathing Exercise for People With Amyotrophic Lateral Sclerosis

University of Alabama at Birmingham

NCT05979688

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 7
Phase 3 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Myasthenia Gravis Trial Landscape

ClinicalTrials.gov lists 33 US studies indexed under Myasthenia Gravis, and 20 of those are currently open to recruitment — roughly 61% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Myasthenia Gravis shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 11 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Myasthenia Gravis is led by argenx with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 33 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Myasthenia Gravis?

PlainTrial tracks 33 US clinical trials for Myasthenia Gravis, of which 20 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Myasthenia Gravis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →