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RECRUITING Phase 3

Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis

NCT07217587 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess how well nipocalimab works when compared to efgartigimod in participants with generalized myasthenia gravis (a condition in which body's immune system mistakenly attacks and damages the connection between nerves and muscles causing muscle weakness).

Conditions Studied

Interventions

  • DRUG Nipocalimab
  • DRUG Efgartigimod

Study Locations (7)

Other

  • Rambam Medical Center — Haifa
  • Sourasky Medical Center — Tel Aviv

Connecticut

  • University of Connecticut — Farmington

Florida

  • SFM Clinical Research LLC — Boca Raton

Illinois

  • HSHS St. Elizabeth's Hospital — O'Fallon

Michigan

  • Henry Ford Hospital — Detroit

North Carolina

  • Atrium Health Wake Forest Baptist — Winston-Salem

Trial Details

FieldValue
Enrollment Target 115 participants
Start Date 2026-01-05
Est. Completion 2028-12-11
Phase Phase 3

Sponsor

Janssen Research & Development

442 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07217587

The ClinicalTrials.gov registry entry for NCT07217587 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 115 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Janssen Research & Development, which has 442 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Myasthenia Gravis appearing as the primary indexed condition, and to 2 interventions — of which Nipocalimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07217587 reports 7 study locations spanning 6 distinct geographic areas — top geographies include Other, Connecticut, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07217587 about?

NCT07217587 is a clinical study titled "Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis". The purpose of this study is to assess how well nipocalimab works when compared to efgartigimod in participants with generalized myasthenia gravis (a condition in which body's immune system mistakenly attacks and damages the connection between nerves and muscles causing muscle weakness).

What is the current status of trial NCT07217587?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 115 participants. The study started on 2026-01-05. Estimated completion is 2028-12-11.

What conditions does trial NCT07217587 study?

This clinical trial studies the following conditions: Myasthenia Gravis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07217587?

The interventions under investigation include: Nipocalimab (DRUG), Efgartigimod (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07217587?

This trial is sponsored by Janssen Research & Development, which has 442 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07217587 being conducted?

This trial has 7 study locations across Connecticut, Florida, Illinois, Michigan, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial