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COMPLETED Phase 2

A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

NCT02965573 · View on ClinicalTrials.gov ↗

Study Summary

This is a randomized, double-blind, placebo-controlled, multicenter Phase II study to evaluate the safety, efficacy, and pharmacokinetics of ARGX-113 for the treatment of autoimmune Myasthenia Gravis (MG) with generalized muscle weakness.

Conditions Studied

Interventions

  • DRUG Placebo
  • BIOLOGICAL ARGX-113

Study Locations (19)

Other

  • Investigator Site 2 — Ghent
  • Investigator Site 1 — Leuven
  • Investigator Site 4 — Montreal
  • Investigator Site 3 — Toronto
  • Investigator Site 7 — Bergamo
  • Investigator Site 6 — Milan
  • Investigator Site 5 — Roma
  • Investigator Site 8 — Leiden
  • Investigator Site 10 — Gdansk
  • Investigator Site 9 — Krakow
  • Investigator Site 12 — Barcelona
  • Investigator Site 11 — Madrid
  • Investigator Site 13 — Solna

California

  • Investigator Site 19 — Irvine
  • Investigator Site 17 — Los Angeles

Florida

  • Investigator Site 15 — Tampa

Indiana

  • Investigator Site 16 — Indianapolis

North Carolina

  • Investigator Site 14 — Chapel Hill

Ohio

  • Investigator Site 18 — Dublin

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2016-12-30
Est. Completion 2017-10-20
Phase Phase 2

Sponsor

argenx

96 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02965573

The ClinicalTrials.gov registry entry for NCT02965573 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is argenx, which has 96 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Myasthenia Gravis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02965573 reports 19 study locations spanning 6 distinct geographic areas — top geographies include Other, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02965573 about?

NCT02965573 is a clinical study titled "A Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness". This is a randomized, double-blind, placebo-controlled, multicenter Phase II study to evaluate the safety, efficacy, and pharmacokinetics of ARGX-113 for the treatment of autoimmune Myasthenia Gravis (MG) with generalized muscle weakness.

What is the current status of trial NCT02965573?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2016-12-30. Estimated completion is 2017-10-20.

What conditions does trial NCT02965573 study?

This clinical trial studies the following conditions: Myasthenia Gravis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02965573?

The interventions under investigation include: Placebo (DRUG), ARGX-113 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02965573?

This trial is sponsored by argenx, which has 96 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02965573 being conducted?

This trial has 19 study locations across California, Florida, Indiana, North Carolina, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial