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NCT07294170 · ClinicalTrials.gov registry record

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

A clinical trial of Myasthenia Gravis and Generalized Myasthenia Gravis, sponsored by argenx.

Recruiting
Registry status
70
Enrollment target
5
Study locations

NCT07294170 is a study of Myasthenia Gravis and Generalized Myasthenia Gravis that is actively recruiting participants, run by argenx. The registered enrollment target is 70 participants, below the 189-participant average among 32 other Myasthenia Gravis trials with a reported enrollment target (63% lower). The trial reports 5 study locations across 5 states.

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The verdict

NCT07294170, a study of Myasthenia Gravis and Generalized Myasthenia Gravis, is actively recruiting participants, sponsored by argenx.

RECRUITING
Registry status
70 participants
Enrollment target
5
Study locations

Study Summary

ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects and improve their quality of life.

Interventions

  • BIOLOGICAL Efgartigimod IV
  • BIOLOGICAL Empasiprubart IV

Study Locations (5)

California

  • Profound Research LLC - Carlsbad - Carlsbad

Florida

  • Visionary Investigators Network - Miami

Maryland

  • Erlanger Health System - Columbia

New York

  • Dent Neurologic Institute - Amherst - Amherst

Texas

  • National Neuromuscular Research Institute - Austin

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2025-12-19
Est. Completion 2028-03-07

Sponsor

argenx

49 total trials

What the Registry Record Tells You About NCT07294170

The ClinicalTrials.gov registry entry for NCT07294170 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 189-participant average among 32 other Myasthenia Gravis trials with a reported enrollment target (63% lower). The listed sponsor is argenx, which has 49 total studies on file at ClinicalTrials.gov.

The record links to 6 conditions, with Myasthenia Gravis appearing as the primary indexed condition, and to 2 interventions - of which Efgartigimod IV is the first listed.

NCT07294170 reports 5 study locations spanning 5 distinct geographic areas - top geographies include California, Florida, Maryland.

Frequently Asked Questions

What is clinical trial NCT07294170 about?

NCT07294170 is a clinical study titled "ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis". ADAPT Forward is a platform study with the aim to look at how safe different drugs are and how well they work for people with myasthenia gravis. The goal is to find the best therapeutic approach to reduce patients' side effects and improve their quality of life.

What is the current status of trial NCT07294170?

This trial is currently recruiting. The enrollment target is 70 participants. The study started on 2025-12-19. Estimated completion is 2028-03-07.

What conditions does trial NCT07294170 study?

This clinical trial studies the following conditions: Myasthenia Gravis, Generalized Myasthenia Gravis, gMG, Generalized Myasthenia Gravis (gMG), MG.

What interventions are being tested in trial NCT07294170?

The interventions under investigation include: Efgartigimod IV (BIOLOGICAL), Empasiprubart IV (BIOLOGICAL).

Who is sponsoring clinical trial NCT07294170?

This trial is sponsored by argenx, which has 49 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07294170 being conducted?

This trial has 5 study locations across California, Florida, Maryland, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.