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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Mucosal Melanoma: early-phase trial registry

2 of 13 indexed Mucosal Melanoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 2 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Mucosal Melanoma: 13 US clinical trials tracked, 2 recruiting.

Mucosal Melanoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 5 of these trials.

Enrollment posture brief

Registry condition mucosal-melanoma

OPEN 2 | RECR 15% | LATE 1 | EARLY 12 | RANK #1315 | SPON 5

Nearest open-share peer: Arthroplasty, Replacement, Knee (15% recruiting · 13 trials)

ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%Mucosal Melanoma (this)15%
Open-enrollment share among volume-matched conditions near Mucosal Melanoma

Mucosal Melanoma lists 2 open slots (15% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Mucosal Melanoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Mucosal Melanoma is recruiting below its size-band peers.

    2 of 13 indexed trials (15.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Mucosal Melanoma research.

    National Cancer Institute (NCI) accounts for 5 of 13 trials (38.5%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Mucosal Melanoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 13 trials that report a genuine target (sentinel values excluded). 9 of those (69.2%) plan for fewer than 100 participants.

  4. Mucosal Melanoma research is mostly interventional.

    13 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 28Phase 31

Open and recent trials

13 total, page 1 of 1

RECRUITING Phase 2 101 participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

National Cancer Institute (NCI)

NCT05111574

RECRUITING Phase 2 20 participants

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

Memorial Sloan Kettering Cancer Center

NCT05384496

ACTIVE NOT RECRUITING Phase 2 313 participants

A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

National Cancer Institute (NCI)

NCT03698019

ACTIVE NOT RECRUITING Phase 1 230 participants

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Ascentage Pharma Group

NCT03611868

ACTIVE NOT RECRUITING Phase 2 72 participants

Dinaciclib in Treating Patients With Stage IV Melanoma

National Cancer Institute (NCI)

NCT00937937

ACTIVE NOT RECRUITING Phase 2 50 participants

Diet and Immune Effects Trial: DIET- A Randomized Double Blinded Dietary Intervention Study in Patients With Metastatic Melanoma Receiving Immunotherapy

M.D. Anderson Cancer Center

NCT04645680

ACTIVE NOT RECRUITING Phase 2 36 participants

Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma

Robert R. McWilliams, MD

NCT03241186

ACTIVE NOT RECRUITING Phase 1 17 participants

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

H. Lee Moffitt Cancer Center and Research Institute

NCT05628883

COMPLETED Phase 3 823 participants

Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT00110019

COMPLETED Phase 2 94 participants

Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma

National Cancer Institute (NCI)

NCT03033576

COMPLETED Phase 1 50 participants

Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists

Craig L Slingluff, Jr

NCT02126579

COMPLETED Phase 2 24 participants

Imatinib in Patients With Mucosal or Acral/Lentiginous Melanoma

Dana-Farber Cancer Institute

NCT00424515

COMPLETED Phase 1 20 participants

A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas

Hoffmann-La Roche

NCT04551352

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 8
Phase 3 1

Named interventions

Most-linked intervention names on Mucosal Melanoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
2 trials
Biospecimen Collection Procedure
2 trials
IFA Other
1 trials
Resiquimod Other
1 trials
PolyICLC Other
1 trials
Peptide Vaccine (LPV7) + Tetanus peptide Biological
1 trials
RO7293583 Drug
1 trials
Phase 1b: APG-115+pembrolizumab Drug
1 trials

US sites by state

Facility locations filed on Mucosal Melanoma trials. A trial with sites in several states counts in each.

California 5 trials
Arkansas 5 trials
Texas 4 trials
Florida 4 trials
Pennsylvania 3 trials
New York 3 trials
Arizona 3 trials
Alabama 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Mucosal Melanoma page

13 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mucosal Melanoma condition card totals 13 registered trials; most-linked intervention Computed Tomography; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.