Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Mucosal Melanoma

Open-data reference.

13 US clinical trials · 2 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 101 participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

National Cancer Institute (NCI)

NCT05111574

RECRUITING Phase 2 20 participants

Axitinib and Nivolumab for the Treatment of Mucosal Melanoma

Memorial Sloan Kettering Cancer Center

NCT05384496

ACTIVE NOT RECRUITING Phase 2 313 participants

A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

National Cancer Institute (NCI)

NCT03698019

ACTIVE NOT RECRUITING Phase 1 230 participants

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Ascentage Pharma Group

NCT03611868

ACTIVE NOT RECRUITING Phase 2 72 participants

Dinaciclib in Treating Patients With Stage IV Melanoma

National Cancer Institute (NCI)

NCT00937937

ACTIVE NOT RECRUITING Phase 2 50 participants

Diet and Immune Effects Trial: DIET- A Randomized Double Blinded Dietary Intervention Study in Patients With Metastatic Melanoma Receiving Immunotherapy

M.D. Anderson Cancer Center

NCT04645680

ACTIVE NOT RECRUITING Phase 2 36 participants

Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma

Robert R. McWilliams, MD

NCT03241186

ACTIVE NOT RECRUITING Phase 1 17 participants

Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma

H. Lee Moffitt Cancer Center and Research Institute

NCT05628883

COMPLETED Phase 3 823 participants

Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery

National Cancer Institute (NCI)

NCT00110019

COMPLETED Phase 2 94 participants

Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma

National Cancer Institute (NCI)

NCT03033576

COMPLETED Phase 1 50 participants

Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists

Craig L Slingluff, Jr

NCT02126579

COMPLETED Phase 2 24 participants

Imatinib in Patients With Mucosal or Acral/Lentiginous Melanoma

Dana-Farber Cancer Institute

NCT00424515

COMPLETED Phase 1 20 participants

A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas

Hoffmann-La Roche

NCT04551352

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 8
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Mucosal Melanoma Trial Landscape

ClinicalTrials.gov lists 13 US studies indexed under Mucosal Melanoma, and 2 of those are currently open to recruitment — roughly 15% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Mucosal Melanoma shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Mucosal Melanoma is led by National Cancer Institute (NCI) with 5 indexed trials, alongside 8 other organizations in the top contributor list. The list on this page surfaces up to 13 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Mucosal Melanoma?

PlainTrial tracks 13 US clinical trials for Mucosal Melanoma, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Mucosal Melanoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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