Ascentage Pharma Group

15 total trials 8 currently recruiting 4 completed

Ascentage Pharma Group sponsors 15 registered US clinical trials on ClinicalTrials.gov, 8 of them currently recruiting, and 4 completed. 4 of these trials are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is CLL/SLL, with 2 trials.

Trial Pipeline

15 total, page 1 of 1

RECRUITING Phase 3

Lisaftoclax (APG-2575) Combined With Azacytidine (AZA) in the Treatment of Patients With Higher-risk Myelodysplastic Syndrome (GLORA-4).

NCT06641414

RECRUITING Phase 3

Study of Olverembatinib (HQP1351) in Patients With CP-CML

NCT06423911

RECRUITING Phase 3

Global Trial in APG2575 for Patients With CLL/SLL

NCT06104566

RECRUITING Phase 3

A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

NCT06051409

RECRUITING Phase 2

A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL

NCT04496349

RECRUITING Phase 1

Study of APG-2575 as a Single Agent or in Combination With Other Therapeutic Agents for CLL/SLL

NCT04215809

RECRUITING Phase 1

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

NCT04260022

RECRUITING Early Phase 1

APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies

NCT03537482

ACTIVE NOT RECRUITING Phase 1

A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

NCT03611868

NOT YET RECRUITING Phase 1

A Study of APG-3288 in Relapsed/Refractory Blood Cancers

NCT07424833

COMPLETED Phase 1

APG-2575 Single Agent or in Combination With Ibrutinib or Rituximab in Patients With Waldenström Macroglobulinemia

NCT04260217

TERMINATED Phase 1

Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer

NCT04210037

COMPLETED Phase 1

APG-1387 in Patients With Advanced Solid Tumors or Hematologic Malignancies

NCT03386526

COMPLETED Phase 1

A Study of APG-1252 in Patients With SCLC or Other Solid Tumors

NCT03080311

COMPLETED Phase 1

APG-115 in Patients With Advanced Solid Tumors or Lymphomas

NCT02935907

What the Pipeline for Ascentage Pharma Group Shows

According to the ClinicalTrials.gov registry, Ascentage Pharma Group is linked to 15 US clinical trials across every stage of research activity. Of those, 8 studies are currently recruiting, about 53% of the sponsor's indexed portfolio, and 4 are already marked complete, representing roughly 27% of the total.

The phase mix for Ascentage Pharma Group reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 11 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Ascentage Pharma Group is CLL/SLL with 2 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.