Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Mitral Valve Regurgitation
Open-data reference.
12 US clinical trials · 4 currently recruiting
Active & Recent Trials
STS/ACC TVT Registry Mitral Module
American College of Cardiology
NCT02245763
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
NCT03242642
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)
Annetine Gelijns
NCT05051033
AltaValve Pivotal Trial
4C Medical Technologies
NCT06465745
MitraClip EXPAND G4 Study
Abbott Medical Devices
NCT04177394
MitraClip REPAIR MR Study
Abbott Medical Devices
NCT04198870
PARTNER 3 Trial - Mitral Valve in Valve
Edwards Lifesciences
NCT03193801
Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System
Shockwave Medical
NCT02276547
The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices
Abbott Medical Devices
NCT03502811
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR
Abbott Medical Devices
NCT07227675
New Techniques to Evaluate Mitral Regurgitation
National Heart, Lung, and Blood Institute (NHLBI)
NCT01063322
Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI
Medical College of Wisconsin
NCT01504880
Phase Distribution
Phase data not available
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Mitral Valve Regurgitation Trial Landscape
ClinicalTrials.gov lists 12 US studies indexed under Mitral Valve Regurgitation, and 4 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Mitral Valve Regurgitation shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Mitral Valve Regurgitation is led by Abbott Medical Devices with 4 indexed trials, alongside 8 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Mitral Valve Regurgitation?
PlainTrial tracks 12 US clinical trials for Mitral Valve Regurgitation, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Mitral Valve Regurgitation?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.