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ClinicalTrials.gov 4 recruiting now small index

Mitral Valve Regurgitation clinical trials

4 of 12 indexed Mitral Valve Regurgitation trials are currently recruiting.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 4 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Mitral Valve Regurgitation: 12 US clinical trials tracked, 4 recruiting.

Mitral Valve Regurgitation is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. The most active sponsor is Abbott Medical Devices, running 4 of these trials.

Enrollment posture brief

Registry condition mitral-valve-regurgitation

OPEN 4 | RECR 33% | LATE 0 | EARLY 0 | RANK #1429 | SPON 4

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Mitral Valve Regurgitati (th…33%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Mitral Valve Regurgitation

Mitral Valve Regurgitation lists 4 open slots (33% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Mitral Valve Regurgitation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Mitral Valve Regurgitation is recruiting below its size-band peers.

    4 of 12 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Mitral Valve Regurgitation research.

    Abbott Medical Devices accounts for 4 of 12 trials (33.3%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Typical Mitral Valve Regurgitation enrolment sits around 450 participants.

    Median target enrolment is 450 among the 12 trials that report a genuine target (sentinel values excluded). 4 of those (33.3%) plan for fewer than 100 participants.

  4. Mitral Valve Regurgitation splits between interventional and observational designs.

    7 interventional and 5 observational studies make up this index (58.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Open and recent trials

12 total, page 1 of 1

RECRUITING 4,000 participants

STS/ACC TVT Registry Mitral Module

American College of Cardiology

NCT02245763

RECRUITING NA 1,056 participants

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

Medtronic Cardiovascular

NCT03242642

RECRUITING NA 450 participants

Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)

Annetine Gelijns

NCT05051033

RECRUITING NA 450 participants

AltaValve Pivotal Trial

4C Medical Technologies

NCT06465745

ACTIVE NOT RECRUITING 1,164 participants

MitraClip EXPAND G4 Study

Abbott Medical Devices

NCT04177394

ACTIVE NOT RECRUITING NA 500 participants

MitraClip REPAIR MR Study

Abbott Medical Devices

NCT04198870

ACTIVE NOT RECRUITING NA 53 participants

PARTNER 3 Trial - Mitral Valve in Valve

Edwards Lifesciences

NCT03193801

ACTIVE NOT RECRUITING NA 27 participants

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

Shockwave Medical

NCT02276547

COMPLETED 1,041 participants

The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices

Abbott Medical Devices

NCT03502811

COMPLETED NA 162 participants

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR

Abbott Medical Devices

NCT07227675

COMPLETED 50 participants

New Techniques to Evaluate Mitral Regurgitation

National Heart, Lung, and Blood Institute (NHLBI)

NCT01063322

COMPLETED 3 participants

Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI

Medical College of Wisconsin

NCT01504880

Phase Distribution

Phase data not available

Named interventions

Most-linked intervention names on Mitral Valve Regurgitation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

MitraClip NTR/XTR System Device
1 trials
MitraClip® NT System Device
1 trials
MitraClip G4 System Device
1 trials
Mitral Valve Repair Surgery Procedure
1 trials
MitraClip™ device implantation Device
1 trials
Edwards SAPIEN 3 transcatheter valve, Model 9600TFX Device
1 trials
Mitral valve replacement Device
1 trials
Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) Device
1 trials

US sites by state

Facility locations filed on Mitral Valve Regurgitation trials. A trial with sites in several states counts in each.

California 8 trials
New York 7 trials
Missouri 6 trials
Illinois 6 trials
North Carolina 5 trials
Florida 5 trials
Ohio 4 trials
Minnesota 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Mitral Valve Regurgitation page

12 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Mitral Valve Regurgitation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Abbott Medical Devices sponsors the most Mitral Valve Regurgitation trials on record, review their full trial history before evaluating a specific study. See Abbott Medical Devices's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mitral Valve Regurgitation condition card totals 12 registered trials; most-linked intervention MitraClip NTR/XTR System; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.