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Mitral Valve Regurgitation clinical trials
4 of 12 indexed Mitral Valve Regurgitation trials are currently recruiting.
12 US clinical trials · 4 currently recruiting
Mitral Valve Regurgitation is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. The most active sponsor is Abbott Medical Devices, running 4 of these trials.
The research picture
Mitral Valve Regurgitation has 12 registered US clinical trials, 4 of them open to new participants right now, about 33% of the total.
- 4
- recruiting participants now
- 33%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Abbott Medical Devices
Active & Recent Trials
12 total, page 1 of 1
STS/ACC TVT Registry Mitral Module
American College of Cardiology
NCT02245763
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Medtronic Cardiovascular
NCT03242642
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)
Annetine Gelijns
NCT05051033
AltaValve Pivotal Trial
4C Medical Technologies
NCT06465745
MitraClip EXPAND G4 Study
Abbott Medical Devices
NCT04177394
MitraClip REPAIR MR Study
Abbott Medical Devices
NCT04198870
PARTNER 3 Trial - Mitral Valve in Valve
Edwards Lifesciences
NCT03193801
Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System
Shockwave Medical
NCT02276547
The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices
Abbott Medical Devices
NCT03502811
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR
Abbott Medical Devices
NCT07227675
New Techniques to Evaluate Mitral Regurgitation
National Heart, Lung, and Blood Institute (NHLBI)
NCT01063322
Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI
Medical College of Wisconsin
NCT01504880
Phase Distribution
Phase data not available
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Mitral Valve Regurgitation Trial Landscape
12 indexed Mitral Valve Regurgitation studies · 4 recruiting (33%).
Phase mix: 0 late (III/IV) vs 0 early (I/II).
Top sponsor: Abbott Medical Devices (4 trials), 8 others listed. 12 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Mitral Valve Regurgitation?
PlainTrial tracks 12 US clinical trials for Mitral Valve Regurgitation, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Mitral Valve Regurgitation?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.