Medtronic Cardiovascular

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Medtronic Cardiovascular sits in the top decile of US sponsors by registered trial count (#407 of 15,742 sponsors by registered trial count).

44 total trials 4 currently recruiting 23 completed top decile by trial count

Medtronic Cardiovascular: 44 sponsored US clinical trials, 4 recruiting.

Medtronic Cardiovascular sponsors 44 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 23 completed. 2 of these trials are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Severe Aortic Stenosis, with 2 trials.

Top-decile sponsor footprint

Medtronic Cardiovascular ranks in the top decile of sponsors by registered trial count (#407 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 25/100

23 of 31 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (74.2%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

44 total, page 1 of 1

RECRUITING

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

NCT06777368

RECRUITING NA

Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

NCT05378347

RECRUITING NA

TTVR Early Feasibility Study

NCT04433065

RECRUITING NA

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

NCT03242642

ACTIVE NOT RECRUITING NA

Evolut™ EXPAND TAVR II Pivotal Trial

NCT05149755

ACTIVE NOT RECRUITING NA

Harmony TPV Post-Approval Study

NCT05077774

ACTIVE NOT RECRUITING NA

SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial

NCT04722250

ACTIVE NOT RECRUITING NA

Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study

NCT03635424

ACTIVE NOT RECRUITING NA

Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients

NCT02701283

ACTIVE NOT RECRUITING NA

Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System

NCT02322840

ACTIVE NOT RECRUITING

Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement

NCT01675440

ACTIVE NOT RECRUITING

ANCHOR (Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System Global Registry)

NCT01534819

ACTIVE NOT RECRUITING NA

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

NCT01586910

TERMINATED NA

Medtronic Evolut™ EXPAND TAVR I Feasibility Study

NCT04639258

COMPLETED

DISSECT-N Post Market Data Collection Registry

NCT04267055

COMPLETED

Optimize PRO Study

NCT04091048

COMPLETED NA

Medtronic CoreValve Evolut R U.S. Clinical Study (Evolut 34R Addendum)

NCT02746809

COMPLETED NA

The Medtronic TAVR 2.0 US Clinical Study

NCT02738853

COMPLETED NA

Valiant Evo US Clinical Trial

NCT02652949

COMPLETED

Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections

NCT02365467

TERMINATED NA

Endurant Evo US Clinical Trial

NCT02393716

COMPLETED NA

Medtronic CoreValve Evolut R U.S. Clinical Study

NCT02207569

COMPLETED NA

Safety and Efficacy of Valiant Mona LSA Stent Graft System

NCT01839695

COMPLETED

Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial

NCT01585779

COMPLETED NA

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

NCT01531374

COMPLETED NA

Endurant Stent Graft System Post Approval Study (ENGAGE PAS)

NCT01379222

COMPLETED NA

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

NCT01240902

COMPLETED NA

Melody® Transcatheter Pulmonary Valve Post-Approval Study

NCT01186692

COMPLETED NA

Study to Evaluate the Clinical Performance of the Valiant Thoracic Stent Graft With the Captivia Delivery System (Valiant Captivia) for the Treatment of Acute, Complicated Type B Aortic Dissections

NCT01114724

COMPLETED NA

Study to Determine if the Valiant Stent Graft is Safe and Effective in Treating Patients Who Have a Blunt Thoracic Aortic Injury

NCT01092767

COMPLETED Phase 4

Graft Patency Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Via Minimally Invasive Coronary Surgery

NCT01334866

TERMINATED NA

ATS 3f(r) Aortic Bioprosthesis Model 1000 Post Approval Study

NCT01116037

TERMINATED NA

Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)

NCT00805948

TERMINATED Phase 2

Evaluation of the Cardioblate Closure Device in Facilitating Occlusion of the Left Atrial Appendage

NCT00841529

COMPLETED NA

Post-Approval Trial of the Talent™ Abdominal Stent Graft to Treat Aortic Aneurysms

NCT00816062

COMPLETED NA

Endurant Bifurcated and Aorto-Uni-Iliac (AUI) Stent Graft System

NCT00705718

COMPLETED NA

The Pivotal Study of the Aptus Endovascular AAA Repair System

NCT00507559

COMPLETED Phase 3

Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) Study

NCT00431834

COMPLETED NA

Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort

NCT00740870

COMPLETED NA

Valor II: The Valiant Thoracic Stent Graft System Clinical Study

NCT00413231

TERMINATED NA

The (PIVOTAL) Study

NCT00444821

COMPLETED Phase 2

VALOR: The Talent Thoracic Stent Graft System Clinical Study

NCT00604799

TERMINATED NA

AneuRx Post Market Study in the Treatment of AAA

NCT00604552

TERMINATED NA

ATS 3f(r) Aortic Bioprosthesis Model 1000, 19mm

NCT00657826

What is open in the Medtronic Cardiovascular pipeline

4 recruiting of 44 indexed (9% open); 23 completed (52%).

Phase mix: 2 late (III/IV) vs 2 early (I/II) (balanced across stages).

Top condition: Severe Aortic Stenosis (2 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Medtronic Cardiovascular: open-pipeline peers nationwide

Peers matched on 44 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Medtronic Cardiovascular sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 020406080 0%2%4%6%8%10% Total trials Recruiting share Medtronic CardiovascularAgios PharmaceuticalsBeth Israel Medical CenterInnovative MedicalKowa Research InstituteAlkermesDBV TechnologiesFlorida Gulf Coast UniversityGenfit
Medtronic Cardiovascular sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Medtronic Cardiovascular sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 44 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this Medtronic Cardiovascular page

44 registered trials is a research-attention snapshot, not an endorsement of Medtronic Cardiovascular or any single study.

  • 4 of Medtronic Cardiovascular's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Severe Aortic Stenosis is the condition Medtronic Cardiovascular studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Severe Aortic Stenosis trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Medtronic Cardiovascular pipeline card: 44 registered trials from official public datasets.Report a data error.