Medtronic Cardiovascular
Medtronic Cardiovascular sponsors 44 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 23 completed. 2 of these trials are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Severe Aortic Stenosis, with 2 trials.
Trial Pipeline
44 total, page 1 of 1
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
NCT06777368
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
NCT05378347
TTVR Early Feasibility Study
NCT04433065
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
NCT03242642
Evolut™ EXPAND TAVR II Pivotal Trial
NCT05149755
Harmony TPV Post-Approval Study
NCT05077774
SMall Annuli Randomized To Evolut™ or SAPIEN™ Trial
NCT04722250
Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study
NCT03635424
Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients
NCT02701283
Transcatheter Mitral Valve Replacement System (TMVR) Pilot Study and The Early Feasibility Study of the TMVR Transseptal System
NCT02322840
Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement
NCT01675440
ANCHOR (Aneurysm Treatment Using the Heli-FX™ EndoAnchor™ System Global Registry)
NCT01534819
Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).
NCT01586910
Medtronic Evolut™ EXPAND TAVR I Feasibility Study
NCT04639258
DISSECT-N Post Market Data Collection Registry
NCT04267055
Optimize PRO Study
NCT04091048
Medtronic CoreValve Evolut R U.S. Clinical Study (Evolut 34R Addendum)
NCT02746809
The Medtronic TAVR 2.0 US Clinical Study
NCT02738853
Valiant Evo US Clinical Trial
NCT02652949
Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections
NCT02365467
Endurant Evo US Clinical Trial
NCT02393716
Medtronic CoreValve Evolut R U.S. Clinical Study
NCT02207569
Safety and Efficacy of Valiant Mona LSA Stent Graft System
NCT01839695
Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial
NCT01585779
Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement
NCT01531374
Endurant Stent Graft System Post Approval Study (ENGAGE PAS)
NCT01379222
Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement
NCT01240902
Melody® Transcatheter Pulmonary Valve Post-Approval Study
NCT01186692
Study to Evaluate the Clinical Performance of the Valiant Thoracic Stent Graft With the Captivia Delivery System (Valiant Captivia) for the Treatment of Acute, Complicated Type B Aortic Dissections
NCT01114724
Study to Determine if the Valiant Stent Graft is Safe and Effective in Treating Patients Who Have a Blunt Thoracic Aortic Injury
NCT01092767
Graft Patency Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Via Minimally Invasive Coronary Surgery
NCT01334866
ATS 3f(r) Aortic Bioprosthesis Model 1000 Post Approval Study
NCT01116037
Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)
NCT00805948
Evaluation of the Cardioblate Closure Device in Facilitating Occlusion of the Left Atrial Appendage
NCT00841529
Post-Approval Trial of the Talent™ Abdominal Stent Graft to Treat Aortic Aneurysms
NCT00816062
Endurant Bifurcated and Aorto-Uni-Iliac (AUI) Stent Graft System
NCT00705718
The Pivotal Study of the Aptus Endovascular AAA Repair System
NCT00507559
Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) Study
NCT00431834
Melody Transcatheter Pulmonary Valve Study: Post Approval Study of the Investigational Device Exemption Cohort
NCT00740870
Valor II: The Valiant Thoracic Stent Graft System Clinical Study
NCT00413231
The (PIVOTAL) Study
NCT00444821
VALOR: The Talent Thoracic Stent Graft System Clinical Study
NCT00604799
AneuRx Post Market Study in the Treatment of AAA
NCT00604552
ATS 3f(r) Aortic Bioprosthesis Model 1000, 19mm
NCT00657826
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 1 |
| Phase 4 | 1 |
What the Pipeline for Medtronic Cardiovascular Shows
According to the ClinicalTrials.gov registry, Medtronic Cardiovascular is linked to 44 US clinical trials across every stage of research activity. Of those, 4 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 23 are already marked complete, representing roughly 52% of the total.
The phase mix for Medtronic Cardiovascular reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 2 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Medtronic Cardiovascular is Severe Aortic Stenosis with 2 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.