Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED NA

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR

NCT07227675 · View on ClinicalTrials.gov ↗

Study Summary

The COAPT Continued Access Study (CAS) is an extension of the COAPT RCT under the same IDE (G120024). COAPT CAS was a single-arm, prospective, multicenter continued access registry that enrolled heart failure patients with secondary mitral regurgitation who remained symptomatic despite optimal guideline-directed medical therapy (GDMT). The objective of the COAPT CAS is to continue the evaluation of safety and effectiveness of the MitraClip NT System under more "real world" conditions in patients who meet the COAPT inclusion/exclusion criteria and who have national Medicare coverage by the Centers for Medicare and Medicaid Services (CMS).

Interventions

  • DEVICE MitraClip® NT System

Study Locations (20)

California

  • Scripps Green Hospital — La Jolla
  • Cedars-Sinai Medical Center — Los Angeles
  • El Camino Hospital — Mountain View
  • Stanford Hospital and Clinics — Stanford

New York

  • NYU Langone Medical Center — New York
  • Columbia University Medical Center / New York Presbyterian Hospital — New York
  • St. Francis Hospital — Roslyn

Florida

  • Mount Sinai Medical Center — Miami
  • Tallahassee Memorial Hospital — Tallahassee

Illinois

  • Northwestern Memorial Hospital — Chicago
  • Rush University Medical Center — Chicago

Missouri

  • Saint Luke's Hospital of Kansas City — Kansas City
  • Barnes Jewish Hospital — St Louis

North Carolina

  • Atrium Health Carolinas Medical Center — Charlotte
  • Duke University Medical Center — Durham

Colorado

  • University of Colorado Hospital — Denver

Georgia

  • Piedmont Hospital Atlanta — Atlanta

Trial Details

FieldValue
Enrollment Target 162 participants
Start Date 2017-10-23
Est. Completion 2024-03-31
Phase NA

Sponsor

Abbott Medical Devices

155 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07227675

The ClinicalTrials.gov registry entry for NCT07227675 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 162 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Abbott Medical Devices, which has 155 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Mitral Regurgitation appearing as the primary indexed condition, and to 1 intervention — of which MitraClip® NT System is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07227675 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, New York, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07227675 about?

NCT07227675 is a clinical study titled "Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR". The COAPT Continued Access Study (CAS) is an extension of the COAPT RCT under the same IDE (G120024). COAPT CAS was a single-arm, prospective, multicenter continued access registry that enrolled heart failure patients with secondary mitral regurgitation who remained symptomatic despite optimal guide...

What is the current status of trial NCT07227675?

This trial is currently completed. It is a NA study. The enrollment target is 162 participants. The study started on 2017-10-23. Estimated completion is 2024-03-31.

What conditions does trial NCT07227675 study?

This clinical trial studies the following conditions: Mitral Regurgitation, Mitral Valve Regurgitation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07227675?

The interventions under investigation include: MitraClip® NT System (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07227675?

This trial is sponsored by Abbott Medical Devices, which has 155 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07227675 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial