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NCT01504880 · ClinicalTrials.gov registry record
Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI
A clinical trial of Mitral Valve Regurgitation and Tricuspid Valve Regurgitation, Non-rheumatic, sponsored by Medical College of Wisconsin.
- Completed
- Registry status
- 3
- Enrollment target
- 1
- Study location
NCT01504880: Completed study of Mitral Valve Regurgitation and Tricuspid Valve Regurgitation, Non-rheumatic, sponsored by Medical College of Wisconsin.
NCT01504880 is a study of Mitral Valve Regurgitation and Tricuspid Valve Regurgitation, Non-rheumatic that has completed, run by Medical College of Wisconsin. The registered enrollment target is 3 participants, below the 814-participant average among 11 other Mitral Valve Regurgitation trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01504880, a study of Mitral Valve Regurgitation and Tricuspid Valve Regurgitation, Non-rheumatic, has completed, sponsored by Medical College of Wisconsin.
- COMPLETED
- Registry status
- 3 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this pilot study is to evaluate mitral (left atrioventricular valve) and tricuspid (right atrioventricular valve (AVV)) regurgitation using cardiac magnetic resonance imaging (CMR) as the non-invasive "gold standard" compared to transthoracic echocardiography (TTE) to evaluate measurements of the width of the regurgitation jet (vena contracta (VC)) to demonstrate the utility of the VC as a means to objectively evaluate atrioventricular valve regurgitation. In addition, feasibility and other quantitative and qualitative measures of regurgitation will be compared between CMR and TTE. * Hypothesis 1: The ability to objectively evaluate atrioventricular valve regurgitation and VC width with TTE and CMR has a high feasibility rate with acceptable intra and inter-observer variability by two independent readers. * Hypothesis 2: There will be positive correlation between the TTE measurement of the VC width and quantitative assessment of atrioventricular valve regurgitation by TTE and CMR. * Hypothesis 3: There will be a positive correlation between the quantitative measurements of atrioventricular valve regurgitation by phase contrast velocity encoded CMR with quantitative values as measured by TTE. * Hypothesis 4: There will be a positive correlation between qualitative assessment of atrioventricular valve regurgitation by CMR compared to TTE.
Primary Outcome
Comparison of the echocardiographic measured vena contracta with quantitative value of mitral or tricuspid regurgitation as measured by MRI.
Conditions Studied
Study Locations (1)
Wisconsin
- Children's Hospital of Wisconsin - Milwaukee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2010-06 |
| Est. Completion | 2019-12-19 |
What the finished NCT01504880 record still lists
NCT01504880 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 814-participant average among 11 other Mitral Valve Regurgitation trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Mitral Valve Regurgitation appearing as the primary indexed condition, and to 0 interventions.
NCT01504880 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT01504880 about?
NCT01504880 is a clinical study titled "Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI". The purpose of this pilot study is to evaluate mitral (left atrioventricular valve) and tricuspid (right atrioventricular valve (AVV)) regurgitation using cardiac magnetic resonance imaging (CMR) as the non-invasive "gold standard" compared to transthoracic echocardiography (TTE) to evaluate measure...
What is the current status of trial NCT01504880?
This trial is currently completed. The enrollment target is 3 participants. The study started on 2010-06. Estimated completion is 2019-12-19.
What conditions does trial NCT01504880 study?
This clinical trial studies the following conditions: Mitral Valve Regurgitation, Tricuspid Valve Regurgitation, Non-rheumatic.
Who is sponsoring clinical trial NCT01504880?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01504880 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01504880's enrollment target sits among peer trials
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Each bar is a band; taller bars hold more other Mitral Valve Regurgitation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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