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ClinicalTrials.gov 7 recruiting now early-phase tilt small index

Methamphetamine Abuse: early-phase trial registry

7 of 16 indexed Methamphetamine Abuse trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,060 of 28,707 conditions by registered trial count.

16 US clinical trials · 7 currently recruiting · #1,060 of 28,707 conditions by registered trial count

Methamphetamine Abuse: 16 US clinical trials tracked, 7 recruiting.

Methamphetamine Abuse is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Affect Therapeutics, running 2 of these trials.

Enrollment posture brief

Registry condition methamphetamine-abuse

OPEN 7 | RECR 44% | LATE 1 | EARLY 6 | RANK #1060 | SPON 2

Nearest open-share peer: Acute Respiratory Distress Syndrome (44% recruiting · 32 trials)

Adolescent62.5%Alcohol Intoxication56.3%Methamphetamine Abuse (this)44%AL Amyloidosis43.8%Allergy18.8%
Open-enrollment share among volume-matched conditions near Methamphetamine Abuse

Methamphetamine Abuse lists 7 open slots (44% of 16 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Methamphetamine Abuse on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Methamphetamine Abuse is recruiting below its size-band peers.

    7 of 16 indexed trials (43.8%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Methamphetamine Abuse trials is spread across many organizations.

    Affect Therapeutics accounts for 2 of 16 trials (12.5%). 11 distinct sponsors appear on at least one study for this condition label.

  3. Typical Methamphetamine Abuse enrolment sits around 80 participants.

    Median target enrolment is 80 among the 16 trials that report a genuine target (sentinel values excluded). 9 of those (56.3%) plan for fewer than 100 participants.

  4. Methamphetamine Abuse research is mostly interventional.

    16 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 23Phase 31

Open and recent trials

16 total, page 1 of 1

RECRUITING NA 600 participants

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

Wake Forest University Health Sciences

NCT04927143

RECRUITING Phase 3 360 participants

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

National Institute on Drug Abuse (NIDA)

NCT06233799

RECRUITING Phase 2 120 participants

Ketamine for Methamphetamine Use Disorder

University of Texas Southwestern Medical Center

NCT06496750

RECRUITING NA 80 participants

Mood and Decision-making in Methamphetamine Use Disorder

Laureate Institute for Brain Research

NCT06410196

RECRUITING NA 50 participants

rTMS for Craving in Methamphetamine Use Disorder

Oregon Health and Science University

NCT03470480

RECRUITING Phase 2 40 participants

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

Clear Scientific

NCT06721494

RECRUITING NA 40 participants

Theta Burst TMS for Treatment of Methamphetamine Use Disorder

Carilion Clinic

NCT06372288

ACTIVE NOT RECRUITING NA 1,283 participants

Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Oregon Health and Science University

NCT05700994

ACTIVE NOT RECRUITING NA 175 participants

Contingency Management for Drug Use: Does Age Matter?

Wake Forest University Health Sciences

NCT05521854

COMPLETED Early Phase 1 113 participants

Exercise in Methamphetamine Use Disorder Upregulation and Neural Function

University of California, Los Angeles

NCT03709667

COMPLETED NA 100 participants

Demonstration of a Digital Care Program for Methamphetamine Use Disorder

Affect Therapeutics

NCT05206175

COMPLETED NA 79 participants

Field Study of a Digital Therapeutic Platform to Facilitate Treatment for Methamphetamine-Primary Stimulant Use Disorder

Affect Therapeutics

NCT05266716

COMPLETED NA 39 participants

Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use

Friends Research Institute

NCT03864653

COMPLETED Early Phase 1 24 participants

Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse

University of Kentucky

NCT01967381

COMPLETED Phase 2 20 participants

Varenicline vs Placebo for the Treatment of Methamphetamine Dependence

University of California, Los Angeles

NCT01011829

COMPLETED Phase 1 9 participants

Buspirone as a Candidate Medication for Methamphetamine Abuse

University of Kentucky

NCT01843205

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 1

Named interventions

Most-linked intervention names on Methamphetamine Abuse records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Methamphetamine Drug
2 trials
Placebo Drug
2 trials
MoodGym Behavioral
1 trials
Methamphetamine (Desoxyn®) Drug
1 trials
Affect Methamphetamine Treatment Program Behavioral
1 trials
Affect Treatment Program for Methamphetamine Use Disorder Other
1 trials
CON Behavioral
1 trials
Standard of Care Contingency Management Behavioral
1 trials

US sites by state

Facility locations filed on Methamphetamine Abuse trials. A trial with sites in several states counts in each.

California 5 trials
Oregon 3 trials
New York 3 trials
Wisconsin 2 trials
Virginia 2 trials
Texas 2 trials
South Carolina 2 trials
Kentucky 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Methamphetamine Abuse page

16 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Methamphetamine Abuse trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Affect Therapeutics sponsors the most Methamphetamine Abuse trials on record, review their full trial history before evaluating a specific study. See Affect Therapeutics's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Methamphetamine Abuse condition card totals 16 registered trials; most-linked intervention Methamphetamine; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.