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ClinicalTrials.gov 7 recruiting now official registry

Methamphetamine Abuse clinical trials

7 of 16 indexed Methamphetamine Abuse trials are currently recruiting.

16 US clinical trials · 7 currently recruiting

Methamphetamine Abuse is the subject of 16 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Affect Therapeutics, running 2 of these trials.

The research picture

Methamphetamine Abuse has 16 registered US clinical trials, 7 of them open to new participants right now, about 44% of the total.

7
recruiting participants now
44%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Affect Therapeutics
Phase 13Phase 23Phase 31

Active & Recent Trials

16 total, page 1 of 1

RECRUITING NA 600 participants

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives

Wake Forest University Health Sciences

NCT04927143

RECRUITING Phase 3 360 participants

Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder

National Institute on Drug Abuse (NIDA)

NCT06233799

RECRUITING Phase 2 120 participants

Ketamine for Methamphetamine Use Disorder

University of Texas Southwestern Medical Center

NCT06496750

RECRUITING NA 80 participants

Mood and Decision-making in Methamphetamine Use Disorder

Laureate Institute for Brain Research

NCT06410196

RECRUITING NA 50 participants

rTMS for Craving in Methamphetamine Use Disorder

Oregon Health and Science University

NCT03470480

RECRUITING Phase 2 40 participants

A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine

Clear Scientific

NCT06721494

RECRUITING NA 40 participants

Theta Burst TMS for Treatment of Methamphetamine Use Disorder

Carilion Clinic

NCT06372288

ACTIVE NOT RECRUITING NA 1,283 participants

Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)

Oregon Health and Science University

NCT05700994

ACTIVE NOT RECRUITING NA 175 participants

Contingency Management for Drug Use: Does Age Matter?

Wake Forest University Health Sciences

NCT05521854

COMPLETED Early Phase 1 113 participants

Exercise in Methamphetamine Use Disorder Upregulation and Neural Function

University of California, Los Angeles

NCT03709667

COMPLETED NA 100 participants

Demonstration of a Digital Care Program for Methamphetamine Use Disorder

Affect Therapeutics

NCT05206175

COMPLETED NA 79 participants

Field Study of a Digital Therapeutic Platform to Facilitate Treatment for Methamphetamine-Primary Stimulant Use Disorder

Affect Therapeutics

NCT05266716

COMPLETED NA 39 participants

Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use

Friends Research Institute

NCT03864653

COMPLETED Early Phase 1 24 participants

Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse

University of Kentucky

NCT01967381

COMPLETED Phase 2 20 participants

Varenicline vs Placebo for the Treatment of Methamphetamine Dependence

University of California, Los Angeles

NCT01011829

COMPLETED Phase 1 9 participants

Buspirone as a Candidate Medication for Methamphetamine Abuse

University of Kentucky

NCT01843205

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Methamphetamine Abuse Trial Landscape

16 indexed Methamphetamine Abuse studies · 7 recruiting (44%).

Phase mix: 1 late (III/IV) vs 6 early (I/II).

Top sponsor: Affect Therapeutics (2 trials), 9 others listed. 16 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Methamphetamine Abuse?

PlainTrial tracks 16 US clinical trials for Methamphetamine Abuse, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Methamphetamine Abuse?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.