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Methamphetamine Abuse clinical trials
Every US clinical trial registered for Methamphetamine Abuse — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
16 US clinical trials · 7 currently recruiting
The research picture
Methamphetamine Abuse has 16 registered US clinical trials, 7 of them open to new participants right now — about 44% of the total.
- 7
- recruiting participants now
- 44%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Affect Therapeutics
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives
Wake Forest University Health Sciences
NCT04927143
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorder
National Institute on Drug Abuse (NIDA)
NCT06233799
Ketamine for Methamphetamine Use Disorder
University of Texas Southwestern Medical Center
NCT06496750
Mood and Decision-making in Methamphetamine Use Disorder
Laureate Institute for Brain Research
NCT06410196
rTMS for Craving in Methamphetamine Use Disorder
Oregon Health and Science University
NCT03470480
A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine
Clear Scientific
NCT06721494
Theta Burst TMS for Treatment of Methamphetamine Use Disorder
Carilion Clinic
NCT06372288
Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM)
Oregon Health and Science University
NCT05700994
Contingency Management for Drug Use: Does Age Matter?
Wake Forest University Health Sciences
NCT05521854
Exercise in Methamphetamine Use Disorder Upregulation and Neural Function
University of California, Los Angeles
NCT03709667
Demonstration of a Digital Care Program for Methamphetamine Use Disorder
Affect Therapeutics
NCT05206175
Field Study of a Digital Therapeutic Platform to Facilitate Treatment for Methamphetamine-Primary Stimulant Use Disorder
Affect Therapeutics
NCT05266716
Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use
Friends Research Institute
NCT03864653
Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse
University of Kentucky
NCT01967381
Varenicline vs Placebo for the Treatment of Methamphetamine Dependence
University of California, Los Angeles
NCT01011829
Buspirone as a Candidate Medication for Methamphetamine Abuse
University of Kentucky
NCT01843205
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Methamphetamine Abuse Trial Landscape
ClinicalTrials.gov lists 16 US studies indexed under Methamphetamine Abuse, and 7 of those are currently open to recruitment — roughly 44% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Methamphetamine Abuse shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Methamphetamine Abuse is led by Affect Therapeutics with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Methamphetamine Abuse?
PlainTrial tracks 16 US clinical trials for Methamphetamine Abuse, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Methamphetamine Abuse?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.