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NCT01843205 · ClinicalTrials.gov registry record · Phase 1

Buspirone as a Candidate Medication for Methamphetamine Abuse

A Phase 1 study of Methamphetamine-dependence and Methamphetamine Abuse, sponsored by University of Kentucky.

Completed
Registry status
Phase 1
Development phase
9
Enrollment target
1
Study location

NCT01843205 is a Phase 1 study of Methamphetamine-dependence and Methamphetamine Abuse that has completed, run by University of Kentucky. The registered enrollment target is 9 participants, below the 106-participant average among 18 other Methamphetamine-dependence trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01843205, a Phase 1 study of Methamphetamine-dependence and Methamphetamine Abuse, has completed, sponsored by University of Kentucky.

COMPLETED
Registry status
Phase 1
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

Methamphetamine use disorders are an unrelenting public health concern. Intensive research efforts have yielded behavioral interventions that reduce methamphetamine use, however, these interventions are not universally effective and treatment effects diminish over time. Development of a pharmacotherapy that enhances the efficacy of these interventions is a priority for the National Institute on Drug Abuse. This study proposes to determine the impact of buspirone maintenance on self-administration of methamphetamine. These preliminary data will be used to support further research developing buspirone as a pharmacotherapy for methamphetamine use disorders. The investigators hypothesize that buspirone will attenuate the reinforcing effects of methamphetamine.

Interventions

  • DRUG Placebo
  • DRUG Methamphetamine

Study Locations (1)

Kentucky

  • University of Kentucky Medical Center - Lexington

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2013-04
Est. Completion 2017-03
Phase Phase 1

Sponsor

University of Kentucky

54 total trials

What the Registry Record Tells You About NCT01843205

The ClinicalTrials.gov registry entry for NCT01843205 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 106-participant average among 18 other Methamphetamine-dependence trials with a reported enrollment target (92% lower). The listed sponsor is University of Kentucky, which has 54 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Methamphetamine-dependence appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT01843205 reports 1 study location spanning 1 distinct geographic area - top geographies include Kentucky.

Frequently Asked Questions

What is clinical trial NCT01843205 about?

NCT01843205 is a clinical study titled "Buspirone as a Candidate Medication for Methamphetamine Abuse". Methamphetamine use disorders are an unrelenting public health concern. Intensive research efforts have yielded behavioral interventions that reduce methamphetamine use, however, these interventions are not universally effective and treatment effects diminish over time. Development of a pharmacother...

What is the current status of trial NCT01843205?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2013-04. Estimated completion is 2017-03.

What conditions does trial NCT01843205 study?

This clinical trial studies the following conditions: Methamphetamine-dependence, Methamphetamine Abuse.

What interventions are being tested in trial NCT01843205?

The interventions under investigation include: Placebo (DRUG), Methamphetamine (DRUG).

Who is sponsoring clinical trial NCT01843205?

This trial is sponsored by University of Kentucky, which has 54 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01843205 being conducted?

This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.