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ClinicalTrials.gov 7 recruiting now official registry

Metastatic Soft Tissue Sarcoma clinical trials

7 of 13 indexed Metastatic Soft Tissue Sarcoma trials are currently recruiting.

13 US clinical trials · 7 currently recruiting

Metastatic Soft Tissue Sarcoma is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Washington University School of Medicine, running 2 of these trials.

The research picture

Metastatic Soft Tissue Sarcoma has 13 registered US clinical trials, 7 of them open to new participants right now, about 54% of the total.

7
recruiting participants now
54%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
2
top sponsor: Washington University School of Medicine
Phase 18Phase 25

Active & Recent Trials

13 total, page 1 of 1

RECRUITING Phase 1 270 participants

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

Adcendo ApS

NCT06797999

RECRUITING Phase 1 250 participants

SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma

Sarcoma Oncology Research Center

NCT03138161

RECRUITING Phase 1 99 participants

Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases

Roswell Park Cancer Institute

NCT03965234

RECRUITING Phase 1 74 participants

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

National Cancer Institute (NCI)

NCT06498648

RECRUITING Phase 2 65 participants

Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas

University of Colorado, Denver

NCT04028063

RECRUITING Phase 1 40 participants

T Cell Membrane-Anchored Tumor-Targeted IL12 -Modified TIL Cell Therapy (attIL12-TIL) for Advanced/Metastatic Soft Tissue and Bone Sarcoma Patients.

M.D. Anderson Cancer Center

NCT06474676

RECRUITING Phase 1 18 participants

Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue Sarcoma

Washington University School of Medicine

NCT06968988

ACTIVE NOT RECRUITING Phase 1 352 participants

Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors

M.D. Anderson Cancer Center

NCT05075993

ACTIVE NOT RECRUITING Phase 2 105 participants

Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma

Washington University School of Medicine

NCT04551430

ACTIVE NOT RECRUITING Phase 2 72 participants

Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

City of Hope Medical Center

NCT04200443

ACTIVE NOT RECRUITING Phase 2 66 participants

Testing Ipilimumab and Nivolumab Combination With or Without Cabozantinib in People >= 18 Years Old With Advanced Soft Tissue Sarcoma

National Cancer Institute LAO

NCT05836571

ACTIVE NOT RECRUITING Phase 1 62 participants

Lurbinectedin + Doxorubicin In Leiomyosarcoma

Massachusetts General Hospital

NCT05099666

COMPLETED Phase 2 209 participants

Sarcoma Study of MORAb-004 Utilization: Research and Clinical Evaluation

Morphotek

NCT01574716

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Metastatic Soft Tissue Sarcoma Trial Landscape

13 indexed Metastatic Soft Tissue Sarcoma studies · 7 recruiting (54%).

Phase mix: 0 late (III/IV) vs 13 early (I/II).

Top sponsor: Washington University School of Medicine (2 trials), 9 others listed. 13 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Metastatic Soft Tissue Sarcoma?

PlainTrial tracks 13 US clinical trials for Metastatic Soft Tissue Sarcoma, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Metastatic Soft Tissue Sarcoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.