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ClinicalTrials.gov 11 recruiting now early-phase tilt

Metastatic Pancreatic Ductal Adenocarcinoma: early-phase trial registry

11 of 21 indexed Metastatic Pancreatic Ductal Adenocarcinoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #797 of 28,707 conditions by registered trial count.

21 US clinical trials · 11 currently recruiting · #797 of 28,707 conditions by registered trial count

Metastatic Pancreatic Ductal Adenocarcinoma: 21 US clinical trials tracked, 11 recruiting.

Metastatic Pancreatic Ductal Adenocarcinoma is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 19 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition metastatic-pancreatic-ductal-adenocarcinoma

OPEN 11 | RECR 52% | LATE 1 | EARLY 19 | RANK #797 | SPON 3

Nearest open-share peer: End-Stage Kidney Disease (52% recruiting · 21 trials)

Metastatic Pancreatic Du (th…52%Anal Cancer42.9%Allergic Conjunctivitis14.3%Attention Deficit Disorder W4.8%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Metastatic Pancreatic Ductal Adenocarcinoma

Metastatic Pancreatic Ductal Adenocarcinoma lists 11 open slots (52% of 21 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Pancreatic Ductal Adenocarcinoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Pancreatic Ductal Adenocarcinoma is recruiting above its size-band peers.

    11 of 21 indexed trials (52.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Metastatic Pancreatic Ductal Adenocarcinoma trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 21 trials (14.3%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Most Metastatic Pancreatic Ductal Adenocarcinoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 51 among the 21 trials that report a genuine target (sentinel values excluded). 15 of those (71.4%) plan for fewer than 100 participants.

  4. Metastatic Pancreatic Ductal Adenocarcinoma research is mostly interventional.

    20 interventional and 1 observational studies make up this index (95.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 111Phase 28Phase 31

Open and recent trials

21 total, page 1 of 1

RECRUITING Phase 1 1,130 participants

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Revolution Medicines

NCT06445062

RECRUITING Phase 2 982 participants

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Pfizer

NCT06989437

RECRUITING Early Phase 1 90 participants

Targeted Pathway Inhibition in Patients With Pancreatic Cancer

OHSU Knight Cancer Institute

NCT04005690

RECRUITING 70 participants

Hyperpolarized 13C MRI to Predict Response in Pancreatic Cancer

University of California, San Francisco

NCT06600906

RECRUITING Phase 1 51 participants

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Washington University School of Medicine

NCT06648434

RECRUITING Phase 2 50 participants

Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma

University of Miami

NCT07096362

RECRUITING Phase 1 43 participants

CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer

National Cancer Institute (NCI)

NCT05685602

RECRUITING Phase 1 35 participants

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Roswell Park Cancer Institute

NCT07214298

RECRUITING Phase 1 24 participants

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

General Oncology

NCT04150042

RECRUITING Phase 2 20 participants

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Benjamin Spieler

NCT06843551

RECRUITING Early Phase 1 12 participants

OMO-103 for the Treatment of Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

OHSU Knight Cancer Institute

NCT07089940

ACTIVE NOT RECRUITING Phase 3 610 participants

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Arcus Biosciences

NCT06608927

ACTIVE NOT RECRUITING Phase 1 120 participants

Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer

Flemming Forsberg

NCT04821284

ACTIVE NOT RECRUITING Phase 1 117 participants

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

M.D. Anderson Cancer Center

NCT02600949

ACTIVE NOT RECRUITING Phase 1 102 participants

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

Erasca

NCT05039177

ACTIVE NOT RECRUITING Phase 2 81 participants

A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer

Agenus

NCT05630183

ACTIVE NOT RECRUITING Phase 2 63 participants

A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy

Memorial Sloan Kettering Cancer Center

NCT04666740

ACTIVE NOT RECRUITING Phase 2 29 participants

A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancer

Memorial Sloan Kettering Cancer Center

NCT06168812

ACTIVE NOT RECRUITING Phase 2 22 participants

BXCL701 and Pembrolizumab in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Georgetown University

NCT05558982

ACTIVE NOT RECRUITING Phase 1 17 participants

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Memorial Sloan Kettering Cancer Center

NCT05642962

COMPLETED Phase 2 22 participants

Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer

Mayo Clinic

NCT04493060

Phase Distribution

PhaseTrial count
Phase 1 11
Phase 2 8
Phase 3 1

Named interventions

Most-linked intervention names on Metastatic Pancreatic Ductal Adenocarcinoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Computed Tomography Procedure
4 trials
Nab-paclitaxel Drug
3 trials
Gemcitabine Drug
3 trials
Biopsy Procedure Procedure
3 trials
Biospecimen Collection Procedure
3 trials
Botensilimab Drug
2 trials
Gemcitabine Hydrochloride Drug
2 trials
Irinotecan Drug
2 trials

US sites by state

Facility locations filed on Metastatic Pancreatic Ductal Adenocarcinoma trials. A trial with sites in several states counts in each.

New York 8 trials
California 7 trials
New Jersey 6 trials
Florida 6 trials
Maryland 4 trials
Massachusetts 4 trials
Illinois 4 trials
Arizona 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Pancreatic Ductal Adenocarcinoma page

21 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Pancreatic Ductal Adenocarcinoma condition card totals 21 registered trials; most-linked intervention Computed Tomography; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.