Agenus
Agenus sponsors 24 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 13 completed. 3 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Advanced Cancer, with 2 trials.
Trial Pipeline
24 total, page 1 of 1
A Study of Botensilimab in Participants With Metastatic Pancreatic Cancer
NCT05630183
A Study of Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma
NCT05529316
A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer
NCT05608044
RaPiDS- A Phase 2 Study of Anti-PD-1 Independently or in Combination With Anti-CTLA-4 in Second-Line Cervical Cancer
NCT03894215
Fc-Engineered Anti-CTLA-4 Monoclonal Antibody in Advanced Cancer
NCT03860272
Study of AGEN1571 in Participants With Advanced Solid Tumors
NCT05377528
A Study Investigating AGEN1777 in Participants With Advanced Solid Tumors
NCT05025085
A Study in Subjects With Advanced Solid Tumors
NCT04156100
Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer
NCT04121676
Phase 1a Study to Evaluate Immunogenicity of ASV®
NCT03673020
Subjects With Metastatic or Locally Advanced Solid Tumors, and Expansion Into Select Solid Tumors (Cervical)
NCT03495882
A Study of AGEN2034 in Advanced Tumors and Cervical Cancer
NCT03104699
Safety and Tolerability Study of AutoSynVax™ Vaccine in Subjects With Advanced Cancer
NCT02992977
AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Participants With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy
NCT02694822
Biological Efficacy Study of HerpV Vaccine With QS-21 to Treat Participants With Recurrent Genital Herpes
NCT01687595
Study of Vitespen (HSPPC-96, Oncophage ®) for Immune Response Assessment in Participants With Resectable Renal Cell Carcinoma at Intermediate Risk of Recurrence
NCT01147536
Study of L-NDDP (Aroplatin) in Patients With Advanced Solid Malignancies or B-Cell Lymphoma
NCT00316511
Trial Evaluating Safety, Tolerability and Immune Response of AG-707
NCT00231049
Clinical Trial Studying a Personalized Cancer Vaccine in Patients With Non-metastatic Kidney Cancer
NCT00126178
AG-858 in Patients Who Are Cytogenetically Positive After Treatment With Gleevec™
NCT00058747
Trial to Compare the Routes of Administration of an Investigational, Personalized, Therapeutic Cancer Vaccine Oncophage (HSPPC-96) in Patients With Metastatic Renal Cell Carcinoma
NCT00082459
Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma
NCT00039000
Survival Study Of Oncophage® vs. Observation In Patients With Kidney Cancer
NCT00033904
A Safety and Effectiveness Study of Vaccine Therapy in Patients With Indolent Lymphoma
NCT00081809
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 12 |
| Phase 2 | 9 |
| Phase 3 | 3 |
What the Pipeline for Agenus Shows
According to the ClinicalTrials.gov registry, Agenus is linked to 24 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 13 are already marked complete, representing roughly 54% of the total.
The phase mix for Agenus reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 21 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Agenus is Advanced Cancer with 2 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.