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NCT06608927 · ClinicalTrials.gov registry record · Phase 3
Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
A Phase 3 study of Metastatic Pancreatic Ductal Adenocarcinoma, sponsored by Arcus Biosciences.
- Active
- Registry status
- Phase 3
- Development phase
- 610
- Enrollment target
- 20
- Study locations
NCT06608927: Active Phase 3 study of Metastatic Pancreatic Ductal Adenocarcinoma, sponsored by Arcus Biosciences.
NCT06608927 is a Phase 3 study of Metastatic Pancreatic Ductal Adenocarcinoma that is active but no longer recruiting, run by Arcus Biosciences. The registered enrollment target is 610 participants, above the 154-participant average among 20 other Metastatic Pancreatic Ductal Adenocarcinoma trials with a reported enrollment target (296% higher). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06608927, a Phase 3 study of Metastatic Pancreatic Ductal Adenocarcinoma, is active but no longer recruiting, sponsored by Arcus Biosciences.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 610 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitabine in all randomized patients.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Gemcitabine
- DRUG Quemliclustat
- DRUG Nab-paclitaxel
Study Locations (20)
California
- University of California San Diego Health - La Jolla
- Cancer & Blood Specialty Clinic - Los Alamitos - Los Alamitos
- Keck Medicine of USC - Keck Hospital of USC - Los Angeles
- Sutter Medical Center - Roseville
- UCSF Helen Diller Family Comprehensive Cancer Center - San Francisco
- UCLA Health - Santa Monica Cancer Care - Santa Monica
Arizona
- Mayo Clinic Arizona - Phoenix Campus - Phoenix
- University of Arizona Cancer Center - Tucson
Florida
- Mayo Clinic - Jacksonville - Jacksonville
- Miami Cancer Institute - Miami
Georgia
- Piedmont Cancer Institute - Atlanta
- Emory University Hospital - Atlanta
Illinois
- USOR - Illinois Cancer Specialists - Arlington Heights - Arlington Heights
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University - Chicago
Colorado
- USOR - Rocky Mountain Cancer Centers - Denver - Midtown - Denver
Connecticut
- Yale Cancer Center - New Haven
Indiana
- Indiana University Melvin and Bren Simon Cancer Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 610 participants |
| Start Date | 2024-12-13 |
| Est. Completion | 2030-11-30 |
| Phase | Phase 3 |
What the registry record for NCT06608927 still lists
NCT06608927 is an interventional study that assigns participants to a tested intervention. The registered 610 participants enrollment target is mid-sized for trials with a published cap, above the 154-participant average among 20 other Metastatic Pancreatic Ductal Adenocarcinoma trials with a reported enrollment target (296% higher).
The record links to 1 condition, with Metastatic Pancreatic Ductal Adenocarcinoma appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT06608927 names 20 study sites across 11 states, led by California, Arizona, Florida.
Frequently Asked Questions
What is clinical trial NCT06608927 about?
NCT06608927 is a clinical study titled "Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma". The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitabine in all randomized patients.
What is the current status of trial NCT06608927?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 610 participants. The study started on 2024-12-13. Estimated completion is 2030-11-30.
What conditions does trial NCT06608927 study?
This clinical trial studies the following conditions: Metastatic Pancreatic Ductal Adenocarcinoma.
What interventions are being tested in trial NCT06608927?
The interventions under investigation include: Placebo (DRUG), Gemcitabine (DRUG), Quemliclustat (DRUG), Nab-paclitaxel (DRUG).
Who is sponsoring clinical trial NCT06608927?
This trial is sponsored by Arcus Biosciences, which has 25 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06608927 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06608927's enrollment target sits among peer trials
610 3rd of 20 higher than 18 of 20 other Metastatic Pancreatic Ductal Adenocarcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Pancreatic Ductal Adenocarcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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