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End-Stage Kidney Disease: early-phase trial registry
11 of 21 indexed End-Stage Kidney Disease trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #797 of 28,707 conditions by registered trial count.
21 US clinical trials · 11 currently recruiting · #797 of 28,707 conditions by registered trial count
End-Stage Kidney Disease: 21 US clinical trials tracked, 11 recruiting.
End-Stage Kidney Disease is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Diality, running 2 of these trials.
Enrollment posture brief
Registry condition end-stage-kidney-disease
OPEN 11 | RECR 52% | LATE 2 | EARLY 6 | RANK #797 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Hearing Loss, Sensorineural (52% recruiting · 21 trials)
End-Stage Kidney Disease lists 11 open slots (52% of 21 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for End-Stage Kidney Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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End-Stage Kidney Disease is recruiting above its size-band peers.
11 of 21 indexed trials (52.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of End-Stage Kidney Disease trials is spread across many organizations.
Diality accounts for 2 of 21 trials (9.5%). 18 distinct sponsors appear on at least one study for this condition label.
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Typical End-Stage Kidney Disease enrolment sits around 100 participants.
Median target enrolment is 100 among the 21 trials that report a genuine target (sentinel values excluded). 10 of those (47.6%) plan for fewer than 100 participants.
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End-Stage Kidney Disease research is mostly interventional.
19 interventional and 2 observational studies make up this index (90.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
21 total, page 1 of 1
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
VA Office of Research and Development
NCT05931276
Symptom Monitoring in Hemodialysis
University of Pennsylvania
NCT05738330
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
CSL Behring
NCT05485961
Incremental Hemodialysis: The TwoPlus Trial
Wake Forest University Health Sciences
NCT05828823
Duke APOL1 Research Biorepository
Duke University
NCT04160507
Pain Reduction Using NEurostimulation Study
Weill Medical College of Cornell University
NCT05311956
Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision
Hennepin Healthcare Research Institute
NCT05879302
Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants
Diality
NCT06613568
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Eli Lilly and Company
NCT07426380
Staged Kidney Transplantation During Combined Heart/Kidney Transplantation
Cedars-Sinai Medical Center
NCT06877169
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
University of California, Los Angeles
NCT05525507
The Arteriovenous Vascular (AV) ACCESS Trial
Wake Forest University Health Sciences
NCT04646226
Virtual Reality in Hemodialysis to Improve Psychological Well-being
University of Illinois at Urbana-Champaign
NCT05642364
Immunological Tolerance in Patients With Mismatched Kidney Transplants
University of California, Los Angeles
NCT05806749
Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)
Merck Sharp & Dohme
NCT05027074
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
Vascular Therapies
NCT02513303
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
Medtronic Endovascular
NCT02363972
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
University of Utah
NCT05614115
Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes
Emory University
NCT05741489
First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical Settings
Diality
NCT06581393
Blood Volume Analysis and Related Outcomes in Hemodialysis
VA New York Harbor Healthcare System
NCT01679249
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 2 |
| Phase 3 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on End-Stage Kidney Disease records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on End-Stage Kidney Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this End-Stage Kidney Disease page
21 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 End-Stage Kidney Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Diality sponsors the most End-Stage Kidney Disease trials on record, review their full trial history before evaluating a specific study. See Diality's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This End-Stage Kidney Disease condition card totals 21 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.