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End-Stage Kidney Disease clinical trials
11 of 21 indexed End-Stage Kidney Disease trials are currently recruiting.
21 US clinical trials · 11 currently recruiting
End-Stage Kidney Disease is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Diality, running 2 of these trials.
The research picture
End-Stage Kidney Disease has 21 registered US clinical trials, 11 of them open to new participants right now, about 52% of the total.
- 11
- recruiting participants now
- 52%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Diality
Active & Recent Trials
21 total, page 1 of 1
CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes
VA Office of Research and Development
NCT05931276
Symptom Monitoring in Hemodialysis
University of Pennsylvania
NCT05738330
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
CSL Behring
NCT05485961
Incremental Hemodialysis: The TwoPlus Trial
Wake Forest University Health Sciences
NCT05828823
Duke APOL1 Research Biorepository
Duke University
NCT04160507
Pain Reduction Using NEurostimulation Study
Weill Medical College of Cornell University
NCT05311956
Shared Decision Making for Kidney Transplant Candidates to Plan for an Organ Offer Decision
Hennepin Healthcare Research Institute
NCT05879302
Moda-flx Hemodialysis System™ Under Professional Care Settings by Trained Individuals and At Home by Participants
Diality
NCT06613568
A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function
Eli Lilly and Company
NCT07426380
Staged Kidney Transplantation During Combined Heart/Kidney Transplantation
Cedars-Sinai Medical Center
NCT06877169
Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants
University of California, Los Angeles
NCT05525507
The Arteriovenous Vascular (AV) ACCESS Trial
Wake Forest University Health Sciences
NCT04646226
Virtual Reality in Hemodialysis to Improve Psychological Well-being
University of Illinois at Urbana-Champaign
NCT05642364
Immunological Tolerance in Patients With Mismatched Kidney Transplants
University of California, Los Angeles
NCT05806749
Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)
Merck Sharp & Dohme
NCT05027074
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
Vascular Therapies
NCT02513303
Percutaneous Less Invasive AV Fistula for Vascular Access in ESRD
Medtronic Endovascular
NCT02363972
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
University of Utah
NCT05614115
Continuous Glucose Monitoring in Patients With End-Stage Kidney Disease and Burnt-Out Diabetes
Emory University
NCT05741489
First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical Settings
Diality
NCT06581393
Blood Volume Analysis and Related Outcomes in Hemodialysis
VA New York Harbor Healthcare System
NCT01679249
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 2 |
| Phase 3 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the End-Stage Kidney Disease Trial Landscape
21 indexed End-Stage Kidney Disease studies · 11 recruiting (52%).
Phase mix: 2 late (III/IV) vs 6 early (I/II).
Top sponsor: Diality (2 trials), 9 others listed. 21 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for End-Stage Kidney Disease?
PlainTrial tracks 21 US clinical trials for End-Stage Kidney Disease, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for End-Stage Kidney Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.