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ClinicalTrials.gov 11 recruiting now official registry

Memory Impairment clinical trials

Every US clinical trial registered for Memory Impairment — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

21 US clinical trials · 11 currently recruiting

The research picture

Memory Impairment has 21 registered US clinical trials, 11 of them open to new participants right now — about 52% of the total.

11
recruiting participants now
52%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: Dartmouth-Hitchcock Medical Center

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING 1,200 participants

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

GAP Innovations, PBC

NCT06584357

RECRUITING NA 360 participants

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Johns Hopkins University

NCT05663034

RECRUITING NA 216 participants

A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses

Arizona State University

NCT05877196

RECRUITING NA 178 participants

NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment

University of California, Berkeley

NCT05986604

RECRUITING NA 160 participants

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

United States Naval Medical Center, San Diego

NCT06413173

RECRUITING NA 150 participants

Brain Health Virtual Reality Study

University of California, San Diego

NCT06124339

RECRUITING NA 125 participants

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Dartmouth-Hitchcock Medical Center

NCT06930846

RECRUITING NA 125 participants

HOBSCOTCH-MS-Efficacy Trial

Dartmouth-Hitchcock Medical Center

NCT06951919

RECRUITING NA 85 participants

Neurobiological Mechanisms of Aging and Stress on Prospective Navigation

Georgia Institute of Technology

NCT03896529

RECRUITING Phase 2 52 participants

Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)

Johns Hopkins University

NCT04601038

RECRUITING 25 participants

Assessing Cognitive Decline at Home

Stanford University

NCT06704971

ACTIVE NOT RECRUITING 400 participants

Quality Improvement and Clinical Utility PrecivityAD2(TM) Clinician Survey

C2N Diagnostics

NCT06025877

ACTIVE NOT RECRUITING NA 10 participants

HOBSCOTCH for People With Post Acute COVID-19 Syndrome (PACS)

Dartmouth-Hitchcock Medical Center

NCT06391489

COMPLETED NA 510 participants

Reducing Disabilities in Alzheimer's Disease (RDAD) Translation in Area Agencies on Aging (AAAs)

University of Washington

NCT01708304

COMPLETED Phase 3 276 participants

Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil

Wake Forest University Health Sciences

NCT02822573

COMPLETED NA 71 participants

Exercise for Memory Rehabilitation in Epilepsy

University of Alabama at Birmingham

NCT04959019

COMPLETED NA 69 participants

Noninvasive Brain Stimulation for Mild Cognitive Impairment

Palo Alto Veterans Institute for Research

NCT03331796

COMPLETED 22 participants

Mental Ability Challenge Study in Adults With and Without HIV

Vanderbilt University Medical Center

NCT03244488

COMPLETED Early Phase 1 20 participants

The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers

AstraZeneca

NCT00985933

COMPLETED Phase 2 20 participants

Effect of Insulin Sensitizer Metformin on AD Biomarkers

University of Pennsylvania

NCT01965756

COMPLETED NA 14 participants

Our Care Wishes - Dementia

University of Pennsylvania

NCT05033262

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 2
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Memory Impairment Trial Landscape

ClinicalTrials.gov lists 21 US studies indexed under Memory Impairment, and 11 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Memory Impairment shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Memory Impairment is led by Dartmouth-Hitchcock Medical Center with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 21 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Memory Impairment?

PlainTrial tracks 21 US clinical trials for Memory Impairment, of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Memory Impairment?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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