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NCT04959019 · ClinicalTrials.gov registry record · NA

Exercise for Memory Rehabilitation in Epilepsy

A NA study of Memory Impairment and Epilepsy, Generalized, sponsored by University of Alabama at Birmingham.

Completed
Registry status
NA
Development phase
71
Enrollment target
1
Study location

NCT04959019: Completed NA study of Memory Impairment and Epilepsy, Generalized, sponsored by University of Alabama at Birmingham.

NCT04959019 is a NA study of Memory Impairment and Epilepsy, Generalized that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 71 participants, below the 201-participant average among 20 other Memory Impairment trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04959019, a NA study of Memory Impairment and Epilepsy, Generalized, has completed, sponsored by University of Alabama at Birmingham.

COMPLETED
Registry status
NA
Development phase
71 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine how effective a 6-week exercise program is for improving memory compared to a no-intervention control group, investigate the brain changes that may be responsible for memory improvements, and determine if the memory benefits and brain changes are retained 6 weeks after completing the exercise intervention in people with Idiopathic generalized epilepsy (IGE).

Primary Outcome

Repeated measures analysis of variance (rm-ANOVA) will be performed to examine condition-by-time interactions for our primary variable of interest, d', which is the discriminability index for delayed recognition memory on the California Verbal Learning Test - II (CVLT-II). Range is negative infinity to positive infinity for estimated interaction effect.

Interventions

  • BEHAVIORAL Supervised combined endurance and resistance training (CERT)
  • BEHAVIORAL Delayed supervised combined endurance and resistance training (CERT)

Study Locations (1)

Alabama

  • University of Alabama at Birmingham - Birmingham

Trial Details

FieldValue
Enrollment Target 71 participants
Start Date 2021-07-21
Est. Completion 2026-02-18
Phase NA
University of Alabama at Birmingham

1,160 total trials

What the finished NCT04959019 record still lists

NCT04959019 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 71 participants, a relatively small participant target, below the 201-participant average among 20 other Memory Impairment trials with a reported enrollment target (65% lower).

The record links to 2 conditions, with Memory Impairment appearing as the primary indexed condition, and to 2 interventions - of which Supervised combined endurance and resistance training (CERT) is the first listed.

NCT04959019 reports a single indexed study location in Alabama.

Frequently Asked Questions

What is clinical trial NCT04959019 about?

NCT04959019 is a clinical study titled "Exercise for Memory Rehabilitation in Epilepsy". The purpose of this study is to determine how effective a 6-week exercise program is for improving memory compared to a no-intervention control group, investigate the brain changes that may be responsible for memory improvements, and determine if the memory benefits and brain changes are retained 6 ...

What is the current status of trial NCT04959019?

This trial is currently completed. It is a NA study. The enrollment target is 71 participants. The study started on 2021-07-21. Estimated completion is 2026-02-18.

What conditions does trial NCT04959019 study?

This clinical trial studies the following conditions: Memory Impairment, Epilepsy, Generalized.

What interventions are being tested in trial NCT04959019?

The interventions under investigation include: Supervised combined endurance and resistance training (CERT) (BEHAVIORAL), Delayed supervised combined endurance and resistance training (CERT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT04959019?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04959019 being conducted?

This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Memory Impairment

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04959019's enrollment target sits among peer trials

71 13th of 20 higher than 8 of 20 other Memory Impairment trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Memory Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04959019, the US trial registry maintained by the National Library of Medicine. NCT04959019 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.