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NCT03244488 · ClinicalTrials.gov registry record
Mental Ability Challenge Study in Adults With and Without HIV
A clinical trial of Cognitive Impairment and HIV-1-infection, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- 22
- Enrollment target
- 1
- Study location
NCT03244488 is a study of Cognitive Impairment and HIV-1-infection that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 22 participants, below the 665-participant average among 105 other Cognitive Impairment trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03244488, a study of Cognitive Impairment and HIV-1-infection, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age. The purpose of this study is to evaluate the contribution of the neuronal cholinergic receptor system to the cognitive impairments seen in adults aging with chronic HIV Infection. By using anti-cholinergic challenge drugs to reversibly "stress" cognitive functioning, the investigators hope to understand whether the presence of the HIV virus in the brain impairs the neural system necessary for normal cognition, more than would be expected from normal cognitive aging.
Conditions Studied
Interventions
- DRUG Scopolamine Injectable Product
- DRUG Mecamylamine Pill
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2015-12 |
| Est. Completion | 2018-12 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03244488
The ClinicalTrials.gov registry entry for NCT03244488 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 665-participant average among 105 other Cognitive Impairment trials with a reported enrollment target (97% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which Scopolamine Injectable Product is the first listed.
NCT03244488 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT03244488 about?
NCT03244488 is a clinical study titled "Mental Ability Challenge Study in Adults With and Without HIV". It is estimated that by 2016, nearly 50% of HIV-positive individuals in the US will be aged 50 or older, and up to 60% of those will experience some degree of cognitive impairment as they age. The purpose of this study is to evaluate the contribution of the neuronal cholinergic receptor system to th...
What is the current status of trial NCT03244488?
This trial is currently completed. The enrollment target is 22 participants. The study started on 2015-12. Estimated completion is 2018-12.
What conditions does trial NCT03244488 study?
This clinical trial studies the following conditions: Cognitive Impairment, HIV-1-infection, Memory Impairment, Aging, Premature, HIV Associated Cognitive Motor Complex.
What interventions are being tested in trial NCT03244488?
The interventions under investigation include: Scopolamine Injectable Product (DRUG), Mecamylamine Pill (DRUG).
Who is sponsoring clinical trial NCT03244488?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03244488 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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