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Mechanical Ventilation: early-phase trial registry
8 of 15 indexed Mechanical Ventilation trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #1,140 of 28,707 conditions by registered trial count.
15 US clinical trials · 8 currently recruiting · #1,140 of 28,707 conditions by registered trial count
Mechanical Ventilation: 15 US clinical trials tracked, 8 recruiting.
Mechanical Ventilation is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is McMaster University, running 2 of these trials.
Enrollment posture brief
Registry condition mechanical-ventilation
OPEN 8 | RECR 53% | LATE 1 | EARLY 2 | RANK #1140 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Beta-Thalassemia (53% recruiting · 15 trials)
Mechanical Ventilation lists 8 open slots (53% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Mechanical Ventilation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Mechanical Ventilation is recruiting above its size-band peers.
8 of 15 indexed trials (53.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Mechanical Ventilation trials is spread across many organizations.
McMaster University accounts for 2 of 15 trials (13.3%). 14 distinct sponsors appear on at least one study for this condition label.
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Typical Mechanical Ventilation enrolment sits around 300 participants.
Median target enrolment is 300 among the 15 trials that report a genuine target (sentinel values excluded). 2 of those (13.3%) plan for fewer than 100 participants.
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Mechanical Ventilation research is mostly interventional.
12 interventional and 3 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
15 total, page 1 of 1
The ED-AWARENESS-2 Trial
Washington University School of Medicine
NCT05534243
RCT: Early Feeding After PEG Placement
Carilion Clinic
NCT04110613
Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Reducing the Number of Ventilator Associated Events, Injury Created by the Ventilator and Unsafe Setting of Alarms.
The University of Texas Medical Branch, Galveston
NCT06737432
Optimizing Pain Treatment in Children On Mechanical Ventilation
Weill Medical College of Cornell University
NCT06994442
Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation
Beth Israel Deaconess Medical Center
NCT07224620
Prognostic Estimates Among ICU Clinicians
Rush University Medical Center
NCT06452797
Analgesia-First Sedation in Trauma Patients
MemorialCare Health System
NCT05751863
The Effects of Endotracheal Suctioning on Pain and Serum Markers
Loma Linda University
NCT06692400
CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients
McMaster University
NCT03471247
Measuring Outcomes of Activity in Intensive Care
Vanderbilt University Medical Center
NCT03115840
Titration of Oxygen Levels During Mechanical Ventilation With Electronic Alerts
Ohio State University
NCT04481581
Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use
Boston Children's Hospital
NCT04263662
CYCLE Pilot Randomized Trial
McMaster University
NCT02377830
Variability Analysis as a Predictor of Liberation From Mechanical Ventilation
The Cleveland Clinic
NCT01140750
The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures
Massachusetts General Hospital
NCT01969227
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Mechanical Ventilation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Mechanical Ventilation trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Mechanical Ventilation page
15 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Mechanical Ventilation trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- McMaster University sponsors the most Mechanical Ventilation trials on record, review their full trial history before evaluating a specific study. See McMaster University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Mechanical Ventilation condition card totals 15 registered trials; most-linked intervention Analgesia-Sedation algorithm; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.