Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Lung Neoplasms

Open-data reference.

24 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING 3,000 participants

Real World Registry for Use of the Ion Endoluminal System

Intuitive Surgical

NCT06004440

RECRUITING 2,000 participants

Specimen Banking From Patients With Lung Cancer

University of Colorado, Denver

NCT01585675

RECRUITING NA 1,160 participants

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

Wake Forest University Health Sciences

NCT04577599

RECRUITING NA 594 participants

TELESCOPE- TELEhealth Shared Decision-making COaching

Rutgers, The State University of New Jersey

NCT05491213

RECRUITING 500 participants

Molecular Analysis of Oncogenes and Resistance Mechanisms in Lung Cancer

University of Colorado, Denver

NCT01580982

RECRUITING Phase 1 100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Cancer Institute (NCI)

NCT06885697

RECRUITING NA 91 participants

TELEhealth Shared Decision-making COaching for Lung Cancer Screening in Primary Care (TELESCOPE) for Hispanics

Rutgers, The State University of New Jersey

NCT07165691

RECRUITING 80 participants

Circulating Tumor Cells (CTC) in Lung Cancer

Shadia Jalal

NCT02630615

RECRUITING Phase 2 60 participants

Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM

Brown University

NCT06974604

ACTIVE NOT RECRUITING Phase 3 870 participants

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

Merck Sharp & Dohme

NCT04380636

ACTIVE NOT RECRUITING Phase 1 32 participants

A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer

Proton Collaborative Group

NCT01770418

ACTIVE NOT RECRUITING Phase 1 15 participants

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

M.D. Anderson Cancer Center

NCT06237881

COMPLETED Phase 3 1,264 participants

Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003, KEYVIBE-003)

Merck Sharp & Dohme

NCT04738487

COMPLETED Phase 3 112 participants

ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting

On Target Laboratories

NCT04241315

COMPLETED 82 participants

Circulating Cytokines as Predictors of Radiation Induced Pulmonary Toxicity

University of Rochester

NCT00178230

COMPLETED Phase 2 63 participants

Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC)

Amgen

NCT00413283

COMPLETED Phase 1 54 participants

Vaccine Treatment for Advanced Non-Small Cell Lung Cancer

NewLink Genetics Corporation

NCT00073398

COMPLETED Phase 2 50 participants

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00001499

COMPLETED Phase 2 48 participants

Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00063219

COMPLETED Phase 1 30 participants

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02897778

COMPLETED Phase 1 30 participants

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02909452

COMPLETED Phase 1 25 participants

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

Pharmacyclics

NCT00120939

COMPLETED Phase 1 8 participants

Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases

University of California, San Diego

NCT01114958

COMPLETED Phase 2

Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)

Pfizer

NCT00034957

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 5
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Lung Neoplasms Trial Landscape

ClinicalTrials.gov lists 24 US studies indexed under Lung Neoplasms, and 9 of those are currently open to recruitment — roughly 38% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Lung Neoplasms shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Lung Neoplasms is led by Syndax Pharmaceuticals with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 24 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Lung Neoplasms?

PlainTrial tracks 24 US clinical trials for Lung Neoplasms, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Lung Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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