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ClinicalTrials.gov 9 recruiting now early-phase tilt

Lung Neoplasms: early-phase trial registry

9 of 24 indexed Lung Neoplasms trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #686 of 28,707 conditions by registered trial count.

24 US clinical trials · 9 currently recruiting · #686 of 28,707 conditions by registered trial count

Lung Neoplasms: 24 US clinical trials tracked, 9 recruiting.

Lung Neoplasms is the subject of 24 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Syndax Pharmaceuticals, running 2 of these trials.

Enrollment posture brief

Registry condition lung-neoplasms

OPEN 9 | RECR 38% | LATE 3 | EARLY 13 | RANK #686 | SPON 2

Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)

Lung Neoplasms (this)38%Aplastic Anemia37.5%Behavior37.5%Allergic Rhinitis8.3%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Lung Neoplasms

Lung Neoplasms lists 9 open slots (38% of 24 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Lung Neoplasms on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Lung Neoplasms is recruiting below its size-band peers.

    9 of 24 indexed trials (37.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Lung Neoplasms trials is spread across many organizations.

    Syndax Pharmaceuticals accounts for 2 of 24 trials (8.3%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Most Lung Neoplasms trials plan to enrol fewer than 100 people.

    Median target enrolment is 80 among the 23 trials that report a genuine target (sentinel values excluded). 14 of those (60.9%) plan for fewer than 100 participants.

  4. Lung Neoplasms research is mostly interventional.

    19 interventional and 5 observational studies make up this index (79.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 18Phase 25Phase 33

Open and recent trials

24 total, page 1 of 1

RECRUITING 3,000 participants

Real World Registry for Use of the Ion Endoluminal System

Intuitive Surgical

NCT06004440

RECRUITING 2,000 participants

Specimen Banking From Patients With Lung Cancer

University of Colorado, Denver

NCT01585675

RECRUITING NA 1,160 participants

Lung B.A.S.E.S. 4 Life Mobile Low-dose Computed Tomography (LDCT) Screening: Ages 40-54

Wake Forest University Health Sciences

NCT04577599

RECRUITING NA 594 participants

TELESCOPE- TELEhealth Shared Decision-making COaching

Rutgers, The State University of New Jersey

NCT05491213

RECRUITING 500 participants

Molecular Analysis of Oncogenes and Resistance Mechanisms in Lung Cancer

University of Colorado, Denver

NCT01580982

RECRUITING Phase 1 100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Cancer Institute (NCI)

NCT06885697

RECRUITING NA 91 participants

TELEhealth Shared Decision-making COaching for Lung Cancer Screening in Primary Care (TELESCOPE) for Hispanics

Rutgers, The State University of New Jersey

NCT07165691

RECRUITING 80 participants

Circulating Tumor Cells (CTC) in Lung Cancer

Shadia Jalal

NCT02630615

RECRUITING Phase 2 60 participants

Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM

Brown University

NCT06974604

ACTIVE NOT RECRUITING Phase 3 870 participants

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

Merck Sharp & Dohme

NCT04380636

ACTIVE NOT RECRUITING Phase 1 32 participants

A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer

Proton Collaborative Group

NCT01770418

ACTIVE NOT RECRUITING Phase 1 15 participants

A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors

M.D. Anderson Cancer Center

NCT06237881

COMPLETED Phase 3 1,264 participants

Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003, KEYVIBE-003)

Merck Sharp & Dohme

NCT04738487

COMPLETED Phase 3 112 participants

ELUCIDATE: Enabling Lung Cancer Identification Using Folate Receptor Targeting

On Target Laboratories

NCT04241315

COMPLETED 82 participants

Circulating Cytokines as Predictors of Radiation Induced Pulmonary Toxicity

University of Rochester

NCT00178230

COMPLETED Phase 2 63 participants

Dose/ Schedule Finding Trial of Romiplostim for Chemotherapy-Induced Thrombocytopenia (CIT) in Non-Small Cell Lung Cancer (NSCLC)

Amgen

NCT00413283

COMPLETED Phase 1 54 participants

Vaccine Treatment for Advanced Non-Small Cell Lung Cancer

NewLink Genetics Corporation

NCT00073398

COMPLETED Phase 2 50 participants

Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer

National Cancer Institute (NCI)

NCT00001499

COMPLETED Phase 2 48 participants

Study Evaluating MAC-321 in Non-small Cell Lung Cancer Refractory to Platinum-based Therapy

Wyeth is now a wholly owned subsidiary of Pfizer

NCT00063219

COMPLETED Phase 1 30 participants

Cardiac Safety Study of Entinostat in Men and Women With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02897778

COMPLETED Phase 1 30 participants

Continuation Study of Entinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Syndax Pharmaceuticals

NCT02909452

COMPLETED Phase 1 25 participants

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

Pharmacyclics

NCT00120939

COMPLETED Phase 1 8 participants

Pilot Study of Intra-Arterial Cisplatin With IV Thiosulfate in Patients With Lung Cancer or Lung Metastases

University of California, San Diego

NCT01114958

COMPLETED Phase 2

Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)

Pfizer

NCT00034957

Phase Distribution

PhaseTrial count
Phase 1 8
Phase 2 5
Phase 3 3

Named interventions

Most-linked intervention names on Lung Neoplasms records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

TELESCOPE, Remote Decision Coaching with Navigation Intervention Behavioral
2 trials
Entinostat Drug
2 trials
Placebo Drug
2 trials
Carboplatin Drug
2 trials
Pembrolizumab Biological
2 trials
Drug: Hyperacute Lung Cancer Cell Vaccine Biological
1 trials
chest radiotherapy Procedure
1 trials
MAC-321 Drug
1 trials

US sites by state

Facility locations filed on Lung Neoplasms trials. A trial with sites in several states counts in each.

Texas 7 trials
Maryland 5 trials
Illinois 5 trials
Florida 5 trials
California 5 trials
Pennsylvania 4 trials
New York 4 trials
Michigan 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Lung Neoplasms page

24 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Lung Neoplasms condition card totals 24 registered trials; most-linked intervention TELESCOPE, Remote Decision Coaching with Navigation Intervention; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.