NewLink Genetics Corporation

31 total trials 17 completed

NewLink Genetics Corporation sponsors 31 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 17 completed. 2 of these trials are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Large Cell Carcinoma, with 1 trials.

Trial Pipeline

31 total, page 1 of 1

COMPLETED Early Phase 1

Single Ascending Dose PK, Oral Bioavailability and Food Effect Study in Healthy Male Volunteers

NCT03852446

TERMINATED Phase 2

A Study of Indoximod or Placebo Plus Pembrolizumab or Nivolumab for Subjects With Unresectable or Metastatic Melanoma

NCT03301636

TERMINATED

Long Term Follow-Up Study for Subjects Previously Treated With Algenpantucel-L (HyperAcute-Pancreas) Immunotherapy

NCT03165188

COMPLETED Phase 1

NLG802 Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors

NCT03164603

COMPLETED Phase 1

A Study of Indoximod in Combination With (7+3) Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02835729

TERMINATED Phase 1

Immunotherapy Combination Study in Advanced Previously Treated Non-Small Cell Lung Cancer

NCT02460367

COMPLETED Phase 1

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

NCT02502708

TERMINATED Phase 1

Alternative Dosing for CRLX101(NLG207) Alone, With Avastin and With mFOLFOX6 in Advanced Solid Tumors

NCT02648711

TERMINATED Phase 1

A Study of CRLX101(NLG207) in Combination With Weekly Paclitaxel in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

NCT02389985

COMPLETED Phase 1

Immunotherapy Study for Metastatic Renal Cell Cancer

NCT02035358

TERMINATED Phase 2

Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer

NCT02405585

TERMINATED Phase 1

Phase 1/2a Dose-Escalation Study of CRLX301 in Patients With Advanced Solid Tumors

NCT02380677

COMPLETED Phase 1

Study of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer

NCT02077881

COMPLETED Phase 2

CRLX101(NLG207) in Combination With Bevacizumab for Metastatic Renal Cell Carcinoma (mRCC) Versus Standard of Care (SOC)

NCT02187302

COMPLETED Phase 1

Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma

NCT02073123

TERMINATED Phase 2

Immunotherapy Study for Patients With Stage IV Melanoma

NCT02054520

COMPLETED Phase 1

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

NCT02052648

TERMINATED Phase 3

Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer

NCT01836432

COMPLETED Phase 2

Study of Chemotherapy in Combination With IDO Inhibitor in Metastatic Breast Cancer

NCT01792050

TERMINATED Phase 2

Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer

NCT01774578

COMPLETED Phase 3

Immunotherapy Study for Surgically Resected Pancreatic Cancer

NCT01072981

TERMINATED Phase 1

IDO Inhibitor Study for Relapsed or Refractory Solid Tumors

NCT00739609

TERMINATED Phase 2

Low Dose Vaccine Study for Surgically Resected Pancreatic Cancer

NCT00614601

COMPLETED Phase 2

Vaccine Study for Surgically Resected Pancreatic Cancer

NCT00569387

TERMINATED Phase 2

Vaccine Maintenance Treatment for Non-Small Cell Lung Cancer

NCT00420732

COMPLETED Phase 1

Study of CRLX101 (NLG207) in the Treatment of Advanced Solid Tumors

NCT00333502

COMPLETED Phase 1

Vaccine Treatment for Advanced Malignant Melanoma

NCT00300612

COMPLETED Phase 1

Vaccine Treatment for Surgically Resected Pancreatic Cancer

NCT00255827

COMPLETED Phase 1

Vaccine Treatment for Hormone Refractory Prostate Cancer

NCT00105053

TERMINATED Phase 1

Vaccine Treatment for Advanced Breast Cancer

NCT00090480

COMPLETED Phase 1

Vaccine Treatment for Advanced Non-Small Cell Lung Cancer

NCT00073398

Phase Distribution

PhaseTrial count
Phase 1 19
Phase 2 9
Phase 3 2

What the Pipeline for NewLink Genetics Corporation Shows

According to the ClinicalTrials.gov registry, NewLink Genetics Corporation is linked to 31 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 17 are already marked complete, representing roughly 55% of the total.

The phase mix for NewLink Genetics Corporation reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 28 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for NewLink Genetics Corporation is Large Cell Carcinoma with 1 linked trial, and 7 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.