Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Long COVID-19 clinical trials
3 of 11 indexed Long COVID-19 trials are currently recruiting.
11 US clinical trials · 3 currently recruiting
Long COVID-19 is the subject of 11 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 5 of these trials.
The research picture
Long COVID-19 has 11 registered US clinical trials, 3 of them open to new participants right now, about 27% of the total.
- 3
- recruiting participants now
- 27%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Duke University
Active & Recent Trials
11 total, page 1 of 1
AT1001 for the Treatment of Long COVID
Massachusetts General Hospital
NCT05747534
Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19
Icahn School of Medicine at Mount Sinai
NCT06960928
A Study to Examine Anktiva for the Treatment of COVID-19.
ImmunityBio
NCT07123727
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
Duke University
NCT06404112
RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)
Duke University
NCT06404099
RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
Duke University
NCT06404060
Long COVID-19 Cutaneous Signatures: An ARPA Funded Research Project
CND Life Sciences
NCT07005947
RECOVER-AUTONOMIC: Platform Protocol, Appendix A (IVIG)
Kanecia Obie Zimmerman
NCT06305793
A Pilot rTMS Trial for Neuropsychiatric Symptoms of Long-COVID
University of California, Los Angeles
NCT06586398
RECOVER-SLEEP: Platform Protocol
Duke University
NCT06404086
RECOVER-NEURO: Platform Protocol, Appendix_A to Measure the Effects of BrainHQ, PASC CoRE and tDCS Interventions on Long COVID Symptoms
Duke University
NCT05965739
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 6 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Long COVID-19 Trial Landscape
11 indexed Long COVID-19 studies · 3 recruiting (27%).
Phase mix: 1 late (III/IV) vs 6 early (I/II).
Top sponsor: Duke University (5 trials), 6 others listed. 11 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Long COVID-19?
PlainTrial tracks 11 US clinical trials for Long COVID-19, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Long COVID-19?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.