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NCT06404060 · ClinicalTrials.gov registry record · NA
RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
A NA study of Long COVID and Long COVID-19, sponsored by Duke University.
- Active
- Registry status
- NA
- Development phase
- 360
- Enrollment target
- 1
- Study location
NCT06404060: Active NA study of Long COVID and Long COVID-19, sponsored by Duke University.
NCT06404060 is a NA study of Long COVID and Long COVID-19 that is active but no longer recruiting, run by Duke University. The registered enrollment target is 360 participants, below the 2,181-participant average among 50 other Long COVID trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06404060, a NA study of Long COVID and Long COVID-19, is active but no longer recruiting, sponsored by Duke University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 360 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management programs and treatment plans if results achieve key study outcomes. This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating interventions to address and improve exercise intolerance and post-exertional malaise (PEM) as manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). The focus of this protocol is to assess interventions that can improve exercise capacity, daily activities tolerance, and quality of life in patients with PASC.
Primary Outcome
The ESWT consists of timed walking on a 10m course. The result is expressed as total walking time after an initial 2-minute warm-up. The ESWT is an outcome measure of exercise capacity.
Conditions Studied
Interventions
- OTHER Education
- BEHAVIORAL Personalized Cardiopulmonary Rehabilitation
Study Locations (1)
North Carolina
- All sites listed under NCT06404047 - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 360 participants |
| Start Date | 2024-07-17 |
| Est. Completion | 2026-05 |
| Phase | NA |
What the registry record for NCT06404060 still lists
NCT06404060 is an interventional study that assigns participants to a tested intervention. The registered 360 participants enrollment target is mid-sized for trials with a published cap, below the 2,181-participant average among 50 other Long COVID trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Long COVID appearing as the primary indexed condition, and to 2 interventions - of which Education is the first listed.
NCT06404060 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06404060 about?
NCT06404060 is a clinical study titled "RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)". This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management programs and treatment plans if results achieve key study outcomes. Thi...
What is the current status of trial NCT06404060?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 360 participants. The study started on 2024-07-17. Estimated completion is 2026-05.
What conditions does trial NCT06404060 study?
This clinical trial studies the following conditions: Long COVID, Long COVID-19.
What interventions are being tested in trial NCT06404060?
The interventions under investigation include: Education (OTHER), Personalized Cardiopulmonary Rehabilitation (BEHAVIORAL).
Who is sponsoring clinical trial NCT06404060?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06404060 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Long COVID
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06404060's enrollment target sits among peer trials
360 9th of 50 higher than 42 of 50 other Long COVID trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Long COVID trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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