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ClinicalTrials.gov 3 recruiting now official registry

Labor Pain clinical trials

Every US clinical trial registered for Labor Pain — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.

15 US clinical trials · 3 currently recruiting

The research picture

Labor Pain has 15 registered US clinical trials, 3 of them open to new participants right now — about 20% of the total.

3
recruiting participants now
20%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
2
top sponsor: Brigham and Women's Hospital

Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.

Active & Recent Trials

RECRUITING Phase 4 988 participants

The Stimulation To Induce Mothers Study

Yale University

NCT05079841

RECRUITING Phase 3 162 participants

Intracervical Balloon Placement With Nitrous Oxide Administration

Maimonides Medical Center

NCT06498908

RECRUITING Phase 4 120 participants

ED90 of Bupivacaine After Lidocaine Test Dose with DPE and EPL

Brigham and Women's Hospital

NCT06146842

COMPLETED NA 411 participants

Best Beginnings for Babies Birth Sister Program Evaluation

Boston Medical Center

NCT02550730

COMPLETED 293 participants

Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia

Northwestern University

NCT00418015

COMPLETED Phase 1 200 participants

Epidural Neostigmine for Labor Pain

Wake Forest University

NCT00779467

COMPLETED Phase 4 179 participants

Comparison of PIEB vs CEI for Labor Analgesia

Duke University

NCT02949271

COMPLETED Phase 4 141 participants

DPE Technique in Labor Epidural for Morbidly Obese Women

Duke University

NCT03074695

COMPLETED NA 101 participants

Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia

Medical University of South Carolina

NCT02412969

COMPLETED Phase 4 100 participants

Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques

Brigham and Women's Hospital

NCT04814537

COMPLETED NA 61 participants

CSE v. Epidural for Postpartum Depression

Grace Lim, MD, MS

NCT03022526

COMPLETED 35 participants

Color Doppler Ultrasound to Locate Needle in Labor Epidural

Augusta University

NCT03596333

COMPLETED NA 24 participants

Stimulation Therapy for Inducing Mothers

Yale University

NCT04756089

COMPLETED NA 20 participants

Virtual Reality Compared to Nitrous Oxide for Labor Analgesia

Brendan Carvalho

NCT04749043

COMPLETED NA 18 participants

Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40

Thomas J. Vernon

NCT02984267

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 1
Phase 4 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Labor Pain Trial Landscape

ClinicalTrials.gov lists 15 US studies indexed under Labor Pain, and 3 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Labor Pain shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Labor Pain is led by Brigham and Women's Hospital with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 15 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Labor Pain?

PlainTrial tracks 15 US clinical trials for Labor Pain, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Labor Pain?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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