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ClinicalTrials.gov 3 recruiting now later-stage tilt small index

Labor Pain: later-stage trial registry

3 of 15 indexed Labor Pain trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 3 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Labor Pain: 15 US clinical trials tracked, 3 recruiting.

Labor Pain is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 2 of these trials.

Enrollment posture brief

Registry condition labor-pain

OPEN 3 | RECR 20% | LATE 6 | EARLY 1 | RANK #1140 | SPON 2

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (20% recruiting · 10 trials)

Advanced Lung Non-Small Cell53.3%AIDS26.7%Labor Pain (this)20%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Labor Pain

Labor Pain lists 3 open slots (20% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Labor Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Labor Pain is recruiting below its size-band peers.

    3 of 15 indexed trials (20%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Labor Pain trials is spread across many organizations.

    Brigham and Women's Hospital accounts for 2 of 15 trials (13.3%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Typical Labor Pain enrolment sits around 120 participants.

    Median target enrolment is 120 among the 15 trials that report a genuine target (sentinel values excluded). 5 of those (33.3%) plan for fewer than 100 participants.

  4. Labor Pain research is mostly interventional.

    13 interventional and 2 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 31Phase 45

Open and recent trials

15 total, page 1 of 1

RECRUITING Phase 4 988 participants

The Stimulation To Induce Mothers Study

Yale University

NCT05079841

RECRUITING Phase 3 162 participants

Intracervical Balloon Placement With Nitrous Oxide Administration

Maimonides Medical Center

NCT06498908

RECRUITING Phase 4 120 participants

ED90 of Bupivacaine After Lidocaine Test Dose with DPE and EPL

Brigham and Women's Hospital

NCT06146842

COMPLETED NA 411 participants

Best Beginnings for Babies Birth Sister Program Evaluation

Boston Medical Center

NCT02550730

COMPLETED 293 participants

Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia

Northwestern University

NCT00418015

COMPLETED Phase 1 200 participants

Epidural Neostigmine for Labor Pain

Wake Forest University

NCT00779467

COMPLETED Phase 4 179 participants

Comparison of PIEB vs CEI for Labor Analgesia

Duke University

NCT02949271

COMPLETED Phase 4 141 participants

DPE Technique in Labor Epidural for Morbidly Obese Women

Duke University

NCT03074695

COMPLETED NA 101 participants

Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia

Medical University of South Carolina

NCT02412969

COMPLETED Phase 4 100 participants

Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques

Brigham and Women's Hospital

NCT04814537

COMPLETED NA 61 participants

CSE v. Epidural for Postpartum Depression

Grace Lim, MD, MS

NCT03022526

COMPLETED 35 participants

Color Doppler Ultrasound to Locate Needle in Labor Epidural

Augusta University

NCT03596333

COMPLETED NA 24 participants

Stimulation Therapy for Inducing Mothers

Yale University

NCT04756089

COMPLETED NA 20 participants

Virtual Reality Compared to Nitrous Oxide for Labor Analgesia

Brendan Carvalho

NCT04749043

COMPLETED NA 18 participants

Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40

Thomas J. Vernon

NCT02984267

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 3 1
Phase 4 5

Named interventions

Most-linked intervention names on Labor Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Bupivacaine Hydrochloride Drug
2 trials
Nitrous oxide Drug
2 trials
Usual maternity care Other
1 trials
Birth Sisters Best Beginnings for Babies Behavioral
1 trials
Dural Puncture Epidural Procedure
1 trials
Lumbar Epidural Procedure
1 trials
Exogenous oxytocin intravenous infusion Other
1 trials
Electronic breast pump Device
1 trials

US sites by state

Facility locations filed on Labor Pain trials. A trial with sites in several states counts in each.

North Carolina 3 trials
Massachusetts 3 trials
Pennsylvania 2 trials
New York 2 trials
Illinois 2 trials
Connecticut 2 trials
South Carolina 1 trials
Georgia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Labor Pain page

15 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Labor Pain condition card totals 15 registered trials; most-linked intervention Bupivacaine Hydrochloride; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.