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Invasive Breast Cancer clinical trials
9 of 20 indexed Invasive Breast Cancer trials are currently recruiting.
20 US clinical trials · 9 currently recruiting
Invasive Breast Cancer is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.
The research picture
Invasive Breast Cancer has 20 registered US clinical trials, 9 of them open to new participants right now, about 45% of the total.
- 9
- recruiting participants now
- 45%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Memorial Sloan Kettering Cancer Center
Active & Recent Trials
20 total, page 1 of 1
Sacituzumab Govitecan In TNBC
Massachusetts General Hospital
NCT04230109
Prospective Breast Cancer Biospecimen Collection
Thomas Jefferson University
NCT04074720
Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
Jonsson Comprehensive Cancer Center
NCT04553770
(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer
Atossa Therapeutics
NCT05607004
Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy
University of California, Davis
NCT06268665
CONFIRM: Magnetic Resonance Guided Radiation Therapy
Brigham and Women's Hospital
NCT04368702
TRUDI: TDXD+Durva in HER2+/Low IBC
Filipa Lynce, MD
NCT05795101
A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT05412225
Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients
Wake Forest University Health Sciences
NCT04677816
Genetic Testing for All Breast Cancer Patients (GET FACTS)
Dana-Farber Cancer Institute
NCT04245176
Olaparib In Metastatic Breast Cancer
Beth Israel Deaconess Medical Center
NCT03344965
Sacituzumab Govitecan +/- Pembrolizumab In HR+ / HER2 - MBC
Ana C Garrido-Castro, MD
NCT04448886
Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
NCT04648904
Onvansertib + Paclitaxel In TNBC
Antonio Giordano, MD
NCT05383196
Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer
Medical College of Wisconsin
NCT04243616
HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
NCT03387553
Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions
Case Comprehensive Cancer Center
NCT02802553
Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ
Memorial Sloan Kettering Cancer Center
NCT00581750
Breast Cancer Genome Guided Therapy Study (BEAUTY)
Mayo Clinic
NCT02022202
Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging
Dartmouth-Hitchcock Medical Center
NCT01060085
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Invasive Breast Cancer Trial Landscape
20 indexed Invasive Breast Cancer studies · 9 recruiting (45%).
Phase mix: 0 late (III/IV) vs 13 early (I/II).
Top sponsor: Memorial Sloan Kettering Cancer Center (3 trials), 9 others listed. 20 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Invasive Breast Cancer?
PlainTrial tracks 20 US clinical trials for Invasive Breast Cancer, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Invasive Breast Cancer?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.