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ClinicalTrials.gov 9 recruiting now early-phase tilt

Invasive Breast Cancer: early-phase trial registry

9 of 20 indexed Invasive Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 9 currently recruiting · #848 of 28,707 conditions by registered trial count

Invasive Breast Cancer: 20 US clinical trials tracked, 9 recruiting.

Invasive Breast Cancer is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 3 of these trials.

Enrollment posture brief

Registry condition invasive-breast-cancer

OPEN 9 | RECR 45% | LATE 0 | EARLY 13 | RANK #848 | SPON 3

Nearest open-share peer: Germ Cell Tumor (45% recruiting · 20 trials)

Advanced or Metastatic Solid55%ALS50%Invasive Breast Cancer (this)45%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Invasive Breast Cancer

Invasive Breast Cancer lists 9 open slots (45% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Invasive Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Invasive Breast Cancer is recruiting above its size-band peers.

    9 of 20 indexed trials (45%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Invasive Breast Cancer research.

    Memorial Sloan Kettering Cancer Center accounts for 3 of 20 trials (15%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Most Invasive Breast Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 86 among the 20 trials that report a genuine target (sentinel values excluded). 13 of those (65%) plan for fewer than 100 participants.

  4. Invasive Breast Cancer research is mostly interventional.

    16 interventional and 4 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 29

Open and recent trials

20 total, page 1 of 1

RECRUITING Phase 2 260 participants

Sacituzumab Govitecan In TNBC

Massachusetts General Hospital

NCT04230109

RECRUITING 200 participants

Prospective Breast Cancer Biospecimen Collection

Thomas Jefferson University

NCT04074720

RECRUITING Phase 2 88 participants

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Jonsson Comprehensive Cancer Center

NCT04553770

RECRUITING Phase 2 87 participants

(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

Atossa Therapeutics

NCT05607004

RECRUITING Phase 2 86 participants

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

University of California, Davis

NCT06268665

RECRUITING NA 70 participants

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Brigham and Women's Hospital

NCT04368702

RECRUITING Phase 2 63 participants

TRUDI: TDXD+Durva in HER2+/Low IBC

Filipa Lynce, MD

NCT05795101

RECRUITING Phase 1 60 participants

A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT05412225

RECRUITING Phase 2 50 participants

Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients

Wake Forest University Health Sciences

NCT04677816

ACTIVE NOT RECRUITING NA 400 participants

Genetic Testing for All Breast Cancer Patients (GET FACTS)

Dana-Farber Cancer Institute

NCT04245176

ACTIVE NOT RECRUITING Phase 2 114 participants

Olaparib In Metastatic Breast Cancer

Beth Israel Deaconess Medical Center

NCT03344965

ACTIVE NOT RECRUITING Phase 2 110 participants

Sacituzumab Govitecan +/- Pembrolizumab In HR+ / HER2 - MBC

Ana C Garrido-Castro, MD

NCT04448886

ACTIVE NOT RECRUITING Early Phase 1 71 participants

Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT04648904

ACTIVE NOT RECRUITING Phase 1 50 participants

Onvansertib + Paclitaxel In TNBC

Antonio Giordano, MD

NCT05383196

ACTIVE NOT RECRUITING Phase 2 36 participants

Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer

Medical College of Wisconsin

NCT04243616

ACTIVE NOT RECRUITING Early Phase 1 31 participants

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03387553

ACTIVE NOT RECRUITING NA 2 participants

Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions

Case Comprehensive Cancer Center

NCT02802553

COMPLETED 550 participants

Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ

Memorial Sloan Kettering Cancer Center

NCT00581750

COMPLETED 140 participants

Breast Cancer Genome Guided Therapy Study (BEAUTY)

Mayo Clinic

NCT02022202

COMPLETED 51 participants

Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging

Dartmouth-Hitchcock Medical Center

NCT01060085

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 9

Named interventions

Most-linked intervention names on Invasive Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Sacituzumab Govitecan Drug
2 trials
Paclitaxel Drug
2 trials
Pembrolizumab Drug
2 trials
Tissue specimen Other
1 trials
Curative Surgery Procedure
1 trials
Dendritic Cell Vaccine (DC1) Biological
1 trials
PDE Imaging system Device
1 trials
Quest near-infrared (NIR) Imaging system Device
1 trials

US sites by state

Facility locations filed on Invasive Breast Cancer trials. A trial with sites in several states counts in each.

Massachusetts 8 trials
New York 4 trials
California 4 trials
Pennsylvania 3 trials
North Carolina 3 trials
Illinois 3 trials
Florida 3 trials
Washington 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Invasive Breast Cancer page

20 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Invasive Breast Cancer condition card totals 20 registered trials; most-linked intervention Sacituzumab Govitecan; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.