Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Invasive Breast Cancer

Open-data reference.

20 US clinical trials · 9 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 260 participants

Sacituzumab Govitecan In TNBC

Massachusetts General Hospital

NCT04230109

RECRUITING 200 participants

Prospective Breast Cancer Biospecimen Collection

Thomas Jefferson University

NCT04074720

RECRUITING Phase 2 88 participants

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Jonsson Comprehensive Cancer Center

NCT04553770

RECRUITING Phase 2 87 participants

(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

Atossa Therapeutics

NCT05607004

RECRUITING Phase 2 86 participants

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

University of California, Davis

NCT06268665

RECRUITING NA 70 participants

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Brigham and Women's Hospital

NCT04368702

RECRUITING Phase 2 63 participants

TRUDI: TDXD+Durva in HER2+/Low IBC

Filipa Lynce, MD

NCT05795101

RECRUITING Phase 1 60 participants

A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT05412225

RECRUITING Phase 2 50 participants

Impact of Vitamin D Supplementation on the Rate of Pathologic Complete Response in Vitamin D Deficient Patients

Wake Forest University Health Sciences

NCT04677816

ACTIVE NOT RECRUITING NA 400 participants

Genetic Testing for All Breast Cancer Patients (GET FACTS)

Dana-Farber Cancer Institute

NCT04245176

ACTIVE NOT RECRUITING Phase 2 114 participants

Olaparib In Metastatic Breast Cancer

Beth Israel Deaconess Medical Center

NCT03344965

ACTIVE NOT RECRUITING Phase 2 110 participants

Sacituzumab Govitecan +/- Pembrolizumab In HR+ / HER2 - MBC

Ana C Garrido-Castro, MD

NCT04448886

ACTIVE NOT RECRUITING Early Phase 1 71 participants

Study of a Shortened Radiation Therapy Schedule in People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT04648904

ACTIVE NOT RECRUITING Phase 1 50 participants

Onvansertib + Paclitaxel In TNBC

Antonio Giordano, MD

NCT05383196

ACTIVE NOT RECRUITING Phase 2 36 participants

Cemiplimab in High-risk or Locally Advanced Luminal and Triple Negative Breast Cancer

Medical College of Wisconsin

NCT04243616

ACTIVE NOT RECRUITING Early Phase 1 31 participants

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03387553

ACTIVE NOT RECRUITING NA 2 participants

Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions

Case Comprehensive Cancer Center

NCT02802553

COMPLETED 550 participants

Molecular Genetic Basis of Invasive Breast Cancer Risk Associated With Lobular Carcinoma in Situ

Memorial Sloan Kettering Cancer Center

NCT00581750

COMPLETED 140 participants

Breast Cancer Genome Guided Therapy Study (BEAUTY)

Mayo Clinic

NCT02022202

COMPLETED 51 participants

Digital Breast Tomosynthesis Versus Contrast Enhanced Magnetic Resonance Imaging (MRI) for Breast Cancer Staging

Dartmouth-Hitchcock Medical Center

NCT01060085

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Invasive Breast Cancer Trial Landscape

ClinicalTrials.gov lists 20 US studies indexed under Invasive Breast Cancer, and 9 of those are currently open to recruitment — roughly 45% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Invasive Breast Cancer shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Invasive Breast Cancer is led by Memorial Sloan Kettering Cancer Center with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 20 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Invasive Breast Cancer?

PlainTrial tracks 20 US clinical trials for Invasive Breast Cancer, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Invasive Breast Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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