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ClinicalTrials.gov 12 recruiting now early-phase tilt

Interstitial Cystitis: early-phase trial registry

12 of 28 indexed Interstitial Cystitis trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #577 of 28,707 conditions by registered trial count.

28 US clinical trials · 12 currently recruiting · #577 of 28,707 conditions by registered trial count

Interstitial Cystitis: 28 US clinical trials tracked, 12 recruiting.

Interstitial Cystitis is the subject of 28 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Corewell Health East, running 4 of these trials.

Enrollment posture brief

Registry condition interstitial-cystitis

OPEN 12 | RECR 43% | LATE 3 | EARLY 8 | RANK #577 | SPON 4

Nearest open-share peer: Acute Myelogenous Leukemia (AML) (43% recruiting · 7 trials)

Interstitial Cystitis (this)43%Anatomic Stage IB Breast Can25%Carcinoma, Hepatocellular25%Autistic Disorder17.9%Cocaine-Related Disorders0%
Open-enrollment share among volume-matched conditions near Interstitial Cystitis

Interstitial Cystitis lists 12 open slots (43% of 28 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Interstitial Cystitis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Interstitial Cystitis is recruiting above its size-band peers.

    12 of 28 indexed trials (42.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Interstitial Cystitis trials is spread across many organizations.

    Corewell Health East accounts for 4 of 28 trials (14.3%). 21 distinct sponsors appear on at least one study for this condition label.

  3. Typical Interstitial Cystitis enrolment sits around 90 participants.

    Median target enrolment is 90 among the 27 trials that report a genuine target (sentinel values excluded). 15 of those (55.6%) plan for fewer than 100 participants.

  4. Interstitial Cystitis research is mostly interventional.

    22 interventional and 6 observational studies make up this index (78.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 25Phase 33

Open and recent trials

28 total, page 1 of 1

RECRUITING 1,000 participants

Identifying Genetic Causes of IC/BPS

Boston Children's Hospital

NCT00389142

RECRUITING 500 participants

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Boston Children's Hospital

NCT00499317

RECRUITING NA 240 participants

EPPIC: Easing Pelvic Pain Interventions Clinical Research Program

State University of New York at Buffalo

NCT05127616

RECRUITING NA 220 participants

Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment

Vanderbilt University Medical Center

NCT06299683

RECRUITING Phase 2 120 participants

Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS

Vaneltix Pharma

NCT05737121

RECRUITING Phase 1 100 participants

Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome

University of Louisville

NCT04845217

RECRUITING Phase 2 100 participants

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

David Sheyn

NCT06096597

RECRUITING NA 75 participants

Investigation of PEMF Therapy for Female Patients With IC/BPS

Wake Forest University Health Sciences

NCT05149573

RECRUITING NA 50 participants

Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome

University of Southern California

NCT04734847

RECRUITING Phase 2 50 participants

Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)

Vaneltix Pharma

NCT06394830

RECRUITING NA 34 participants

Acupuncture First for IC/BPS

University Hospitals Cleveland Medical Center

NCT06366269

RECRUITING Early Phase 1 30 participants

Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis

Wake Forest University Health Sciences

NCT04734106

ACTIVE NOT RECRUITING NA 144 participants

Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)

Medtronic - MITG

NCT05696444

ACTIVE NOT RECRUITING Phase 3 26 participants

A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain

Jocelyn Fitzgerald

NCT05658874

ACTIVE NOT RECRUITING Early Phase 1 5 participants

Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome

Stanford University

NCT05485207

COMPLETED 2,923 participants

The Women's Urology Center/WISH Database Project

Corewell Health East

NCT00379002

COMPLETED NA 2,511 participants

Rapid Molecular Organism Identification and Mixed Flora Antibiotic Resistance Profiling (MixAR) Prospective Study

Pathnostics

NCT03931538

COMPLETED 666 participants

Assessing Chronic Pain Conditions in Patients (Pts) With and Without (w&wo) Interstitial Cystitis

Corewell Health East

NCT01138800

COMPLETED Phase 3 271 participants

Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00124306

COMPLETED NA 97 participants

Mindfulness and Yoga for Pain With Interstitial Cystitis Evaluation

University of New Mexi

NCT04820855

COMPLETED Phase 3 90 participants

Clinical Trial Comparing Two Bladder Instillations for IC/BPS

Olivia Cardenas-Trowers, M.D.

NCT03463915

COMPLETED Phase 2 90 participants

Study of U101 for Bladder Pain and/or Urgency

Urigen

NCT00256542

COMPLETED NA 24 participants

Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain

Summa Health System

NCT00554320

COMPLETED 15 participants

Urinary Biomarkers Characteristic to Interstitial Cystitis

Corewell Health East

NCT00971568

COMPLETED NA 14 participants

The Effects of Mindfulness-based Stress Reduction in Interstitial Cystitis Patients

TriHealth

NCT03722992

COMPLETED NA 14 participants

Intravesical Liposomes for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)

Kenneth Peters, MD

NCT01731470

COMPLETED Phase 2 10 participants

Study of Biomarkers and the Relaxation Response Using Guided Imagery in Women With IC

Corewell Health East

NCT00420550

COMPLETED

Genetics of Interstitial Cystitis

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT00237081

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 5
Phase 3 3

Named interventions

Most-linked intervention names on Interstitial Cystitis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

VNX001 Drug
2 trials
Placebo Drug
2 trials
Liposomes Biological
1 trials
Alkalinized Lidocaine-Heparin Drug
1 trials
MBSR Other
1 trials
Relaxation Response using Guided Imagery Behavioral
1 trials
Bladder instillation WITHOUT triamcinolone acetonide Drug
1 trials
Bladder instillation WITH triamcinolone acetonide Drug
1 trials

US sites by state

Facility locations filed on Interstitial Cystitis trials. A trial with sites in several states counts in each.

Michigan 9 trials
California 8 trials
Ohio 5 trials
New York 5 trials
North Carolina 5 trials
Pennsylvania 3 trials
Massachusetts 3 trials
Illinois 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Interstitial Cystitis page

28 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 12 Interstitial Cystitis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Corewell Health East sponsors the most Interstitial Cystitis trials on record, review their full trial history before evaluating a specific study. See Corewell Health East's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Interstitial Cystitis condition card totals 28 registered trials; most-linked intervention VNX001; top US site state Michigan. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.