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Interstitial Cystitis clinical trials
Every US clinical trial registered for Interstitial Cystitis — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
28 US clinical trials · 12 currently recruiting
The research picture
Interstitial Cystitis has 28 registered US clinical trials, 12 of them open to new participants right now — about 43% of the total.
- 12
- recruiting participants now
- 43%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Corewell Health East
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Identifying Genetic Causes of IC/BPS
Boston Children's Hospital
NCT00389142
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Boston Children's Hospital
NCT00499317
EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
State University of New York at Buffalo
NCT05127616
Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment
Vanderbilt University Medical Center
NCT06299683
Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
Vaneltix Pharma
NCT05737121
Peppermint Oil for the Treatment of Interstitial Cystitis / Bladder Pain Syndrome
University of Louisville
NCT04845217
Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome
David Sheyn
NCT06096597
Investigation of PEMF Therapy for Female Patients With IC/BPS
Wake Forest University Health Sciences
NCT05149573
Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome
University of Southern California
NCT04734847
Safety, Efficacy, and Frequency of Administration of VNX001 in the Treatment of Interstitial Cystitis / Bladder Pain Syndrome (IC/BPS)
Vaneltix Pharma
NCT06394830
Acupuncture First for IC/BPS
University Hospitals Cleveland Medical Center
NCT06366269
Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis
Wake Forest University Health Sciences
NCT04734106
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
Medtronic - MITG
NCT05696444
A Multidisciplinary, Multimodal Bundled Care Approach to Chronic Pelvic Pain
Jocelyn Fitzgerald
NCT05658874
Transvaginal Botulinum Toxin A for Interstitial Cystitis / Bladder Pain Syndrome
Stanford University
NCT05485207
The Women's Urology Center/WISH Database Project
Corewell Health East
NCT00379002
Rapid Molecular Organism Identification and Mixed Flora Antibiotic Resistance Profiling (MixAR) Prospective Study
Pathnostics
NCT03931538
Assessing Chronic Pain Conditions in Patients (Pts) With and Without (w&wo) Interstitial Cystitis
Corewell Health East
NCT01138800
Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00124306
Mindfulness and Yoga for Pain With Interstitial Cystitis Evaluation
University of New Mexi
NCT04820855
Clinical Trial Comparing Two Bladder Instillations for IC/BPS
Olivia Cardenas-Trowers, M.D.
NCT03463915
Study of U101 for Bladder Pain and/or Urgency
Urigen
NCT00256542
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
Summa Health System
NCT00554320
Urinary Biomarkers Characteristic to Interstitial Cystitis
Corewell Health East
NCT00971568
The Effects of Mindfulness-based Stress Reduction in Interstitial Cystitis Patients
TriHealth
NCT03722992
Intravesical Liposomes for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS)
Kenneth Peters, MD
NCT01731470
Study of Biomarkers and the Relaxation Response Using Guided Imagery in Women With IC
Corewell Health East
NCT00420550
Genetics of Interstitial Cystitis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00237081
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 5 |
| Phase 3 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Interstitial Cystitis Trial Landscape
ClinicalTrials.gov lists 28 US studies indexed under Interstitial Cystitis, and 12 of those are currently open to recruitment — roughly 43% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Interstitial Cystitis shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Interstitial Cystitis is led by Corewell Health East with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 28 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Interstitial Cystitis?
PlainTrial tracks 28 US clinical trials for Interstitial Cystitis, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Interstitial Cystitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.