Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05499741 · ClinicalTrials.gov registry record · NA
Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder
A NA study of Insomnia and Tourette's Disorder, sponsored by University of California, Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT05499741: Recruiting NA study of Insomnia and Tourette's Disorder, sponsored by University of California, Los Angeles.
NCT05499741 is a NA study of Insomnia and Tourette's Disorder that is actively recruiting participants, run by University of California, Los Angeles. The registered enrollment target is 25 participants, below the 170-participant average among 151 other Insomnia trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05499741, a NA study of Insomnia and Tourette's Disorder, is actively recruiting participants, sponsored by University of California, Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder. This project will also examine the effects of the device on depression, anxiety, and daytime sleepiness, and explore its effects on tic severity.
Primary Outcome
Sleep onset latency will be measured via a wrist actigraph and is defined as duration in minutes between time in bed and sleep onset. An actigraph (Actiwatch Spectrum PRO, Philips Respironics, Amsterdam, Netherlands), worn on the non-dominant wrist, will record daily and nightly movement/activity. Actigraphs will be set to record movements in 30-second epochs. Actigraphy data will be converted into sleep-wake scores guided by sleep diary bed times and rise times.
Conditions Studied
Interventions
- DEVICE Forehead Temperature-Regulating Therapy
Study Locations (1)
California
- Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-04-27 |
| Est. Completion | 2026-01 |
| Phase | NA |
What NCT05499741 shows while recruiting
NCT05499741 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 170-participant average among 151 other Insomnia trials with a reported enrollment target (85% lower).
The record links to 2 conditions, with Insomnia appearing as the primary indexed condition, and to 1 intervention - of which Forehead Temperature-Regulating Therapy is the first listed.
NCT05499741 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05499741 about?
NCT05499741 is a clinical study titled "Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder". The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder. This project will also examine the effects of the device on depression...
What is the current status of trial NCT05499741?
This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2023-04-27. Estimated completion is 2026-01.
What conditions does trial NCT05499741 study?
This clinical trial studies the following conditions: Insomnia, Tourette's Disorder.
What interventions are being tested in trial NCT05499741?
The interventions under investigation include: Forehead Temperature-Regulating Therapy (DEVICE).
Who is sponsoring clinical trial NCT05499741?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05499741 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Insomnia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05499741's enrollment target sits among peer trials
25 131st of 151 higher than 21 of 151 other Insomnia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Insomnia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Treatments for Insomnia in Veterans With PTSD
RECRUITING · NA
-
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
RECRUITING · NA
-
mPATH for Low-income Older Adults
RECRUITING · NA
-
Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD
RECRUITING · NA
-
Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study
RECRUITING · NA
-
Treatments in Women Veterans With Insomnia and PTSD
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01166854 · 25 participants
Characterization of Familial Myopathy and Paget Disease of Bone
- NCT01913106 · 25 participants · Phase 1
HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
- NCT02138669 · 25 participants · NA
Intacs Prescription Inserts for Keratoconus Patients
- NCT02174549 · 25 participants · Phase 1
Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI