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ClinicalTrials.gov 27 recruiting now full pipeline

Inflammatory Bowel Diseases: full-pipeline trial registry

27 of 49 indexed Inflammatory Bowel Diseases trials are currently recruiting.

Corpus placement: #281 of 28,707 conditions by registered trial count.

49 US clinical trials · 27 currently recruiting · #281 of 28,707 conditions by registered trial count

Inflammatory Bowel Diseases: 49 US clinical trials tracked, 27 recruiting.

Inflammatory Bowel Diseases is the subject of 49 registered US clinical trials on ClinicalTrials.gov, 27 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 4 of these trials.

Enrollment posture brief

Registry condition inflammatory-bowel-diseases

OPEN 27 | RECR 55% | LATE 6 | EARLY 9 | RANK #281 | SPON 4

Nearest open-share peer: Diffuse Intrinsic Pontine Glioma (55% recruiting · 29 trials)

Inflammatory Bowel Disea (th…55%Diet, Healthy49%Duchenne Muscular Dystrophy44.9%Chronic Disease36.7%Arthritis30.6%
Open-enrollment share among volume-matched conditions near Inflammatory Bowel Diseases

Inflammatory Bowel Diseases lists 27 open slots (55% of 49 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Inflammatory Bowel Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Inflammatory Bowel Diseases is recruiting above its size-band peers.

    27 of 49 indexed trials (55.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Inflammatory Bowel Diseases trials is spread across many organizations.

    Massachusetts General Hospital accounts for 4 of 49 trials (8.2%). 38 distinct sponsors appear on at least one study for this condition label.

  3. Typical Inflammatory Bowel Diseases enrolment sits around 96 participants.

    Median target enrolment is 96 among the 49 trials that report a genuine target (sentinel values excluded). 25 of those (51%) plan for fewer than 100 participants.

  4. Inflammatory Bowel Diseases research is mostly interventional.

    36 interventional and 13 observational studies make up this index (73.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 23Phase 33Phase 43

Open and recent trials

49 total, page 1 of 1

RECRUITING 2,000,000 participants

Observational Pharmaco-Epidemiology Research & Analysis

Epividian

NCT03813862

RECRUITING 1,200 participants

The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

University of Chicago

NCT01280825

RECRUITING 1,000 participants

Registry and Biorepository for IBD in Central Texas

University of Texas at Austin

NCT04617184

RECRUITING Phase 2 645 participants

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

Spyre Therapeutics

NCT07012395

RECRUITING 400 participants

Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease

Montefiore Medical Center

NCT06266663

RECRUITING 400 participants

The Effect of IBD Flares on Serum PSA

Northwestern University

NCT03558048

RECRUITING Phase 2 385 participants

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

NCT06226883

RECRUITING 200 participants

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

Seattle Children's Hospital

NCT06315179

RECRUITING NA 150 participants

Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease

NYU Langone Health

NCT06309017

RECRUITING Phase 3 150 participants

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

Eli Lilly and Company

NCT04844606

RECRUITING NA 137 participants

BOOM-IBD2 Pivotal Clinical Trial

Boomerang Medical

NCT06571669

RECRUITING NA 128 participants

Heart Rate Variability and Inflammatory Bowel Disease

Emory University

NCT06537258

RECRUITING Phase 3 120 participants

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

Weill Medical College of Cornell University

NCT06274554

RECRUITING Phase 1 116 participants

Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

Children's Hospital Medical Center, Cincinnati

NCT03847467

RECRUITING NA 80 participants

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

Massachusetts General Hospital

NCT05332639

RECRUITING NA 68 participants

IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms

University of Michigan

NCT06094608

RECRUITING NA 60 participants

Feasibility Test of Action Planning in Pediatric IBD

University of North Carolina, Chapel Hill

NCT06186752

RECRUITING 60 participants

Therapeutic Endpoint in Pediatric IBD Conditions

Children's National Research Institute

NCT06065228

RECRUITING NA 60 participants

Regulation of Mucosal Healing in Inflammatory Bowel Disease

Terrence A Barrett

NCT04504136

RECRUITING NA 40 participants

Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients

University of Michigan

NCT06188793

RECRUITING NA 40 participants

Outpatient VR (Virtual Reality)-Brain-gut Behavioral Therapies (BGBT) in Inflammatory Bowel Disease (IBD)

University of Michigan

NCT06910787

RECRUITING NA 30 participants

A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

Massachusetts General Hospital

NCT07219537

RECRUITING NA 30 participants

VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

University of Louisville

NCT03953768

RECRUITING NA 21 participants

Fermented Food-Supplemented Diet in Ulcerative Colitis

Stanford University

NCT04401605

RECRUITING Phase 1 20 participants

Beta-Hydroxybutyrate Feasibility Treating IBD

University of Texas at Austin

NCT06351124

RECRUITING Early Phase 1 15 participants

Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

Stanford University

NCT05912387

RECRUITING NA 10 participants

Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

Massachusetts General Hospital

NCT07033208

ACTIVE NOT RECRUITING 15,000 participants

A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease

Target PharmaSolutions

NCT03251118

ACTIVE NOT RECRUITING 4,970 participants

A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease

Janssen Biotech

NCT00606346

ACTIVE NOT RECRUITING Phase 2 280 participants

A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC

Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

NCT05611671

ACTIVE NOT RECRUITING Phase 4 124 participants

Proactive Infliximab Optimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patients With Inflammatory Bowel Disease: The OPTIMIZE Trial

Beth Israel Deaconess Medical Center

NCT04835506

ACTIVE NOT RECRUITING NA 123 participants

A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy

University of Maryland, Baltimore

NCT05316584

ACTIVE NOT RECRUITING NA 15 participants

Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe

Massachusetts General Hospital

NCT04565821

COMPLETED Phase 3 961 participants

A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

Janssen Research & Development

NCT02407236

COMPLETED 472 participants

Monitoring Serologic Response to Severe Acute Respiratory Syndrome-2 (SARS-COV-2)/COVID-19 in Children

Connecticut Children's Medical Center

NCT04838834

COMPLETED NA 222 participants

Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions

Duke University

NCT03938324

COMPLETED 120 participants

The Deep South Surgical Equity Research Network: Addressing Socioecological Determinants of Health

University of Alabama at Birmingham

NCT05345054

COMPLETED Phase 4 102 participants

Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®)

Cedars-Sinai Medical Center

NCT03723447

COMPLETED 96 participants

Cytokines and Genes in Therapeutic Response in Crohn's Disease

Vanderbilt University Medical Center

NCT03266471

COMPLETED NA 84 participants

Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System

Capso Vision

NCT04573959

COMPLETED 77 participants

Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease

Dartmouth-Hitchcock Medical Center

NCT03799471

COMPLETED Phase 1 60 participants

Multiple Dose Ethnobridging PK Study in Healthy Subjects

Theravance Biopharma

NCT03750565

COMPLETED NA 55 participants

A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease

University of Washington

NCT05651542

COMPLETED Phase 1 49 participants

A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation

Bristol-Myers Squibb

NCT03254784

COMPLETED NA 45 participants

SMART-IBD App Trial

Children's Hospital Medical Center, Cincinnati

NCT06023667

COMPLETED NA 43 participants

Health Coaching as a Tool for Improving Medication Adherence in Adult Patients With Inflammatory Bowel Disease

Vanderbilt University Medical Center

NCT03757533

COMPLETED Phase 4 41 participants

Examining the Effect of Ondansetron on Bowel Prep Success

State University of New York - Downstate Medical Center

NCT05439772

COMPLETED NA 30 participants

Digital Behavioral Interventions in Inflammatory Bowel Disease

Montefiore Medical Center

NCT04861597

COMPLETED Phase 1 15 participants

Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis

Stacy A. Kahn

NCT02330653

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 3
Phase 3 3
Phase 4 3

Named interventions

Most-linked intervention names on Inflammatory Bowel Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
4 trials
MORF-057 Drug
2 trials
Placebo Other
2 trials
Fecal Microbiota Transplant (FMT) Biological
1 trials
Digital mood tracking Behavioral
1 trials
Internet based cognitive behavioral therapy Behavioral
1 trials
Bupivacaine/epinephrine/dexamethasone Drug
1 trials
BMS-986165 Tablet Drug
1 trials

US sites by state

Facility locations filed on Inflammatory Bowel Diseases trials. A trial with sites in several states counts in each.

California 13 trials
New York 9 trials
Massachusetts 9 trials
Texas 8 trials
North Carolina 8 trials
Florida 7 trials
Tennessee 6 trials
Georgia 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Inflammatory Bowel Diseases page

49 registered trials, 27 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Inflammatory Bowel Diseases condition card totals 49 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.