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Inflammatory Bowel Diseases clinical trials
Every US clinical trial registered for Inflammatory Bowel Diseases — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
49 US clinical trials · 27 currently recruiting
The research picture
Inflammatory Bowel Diseases has 49 registered US clinical trials, 27 of them open to new participants right now — about 55% of the total.
- 27
- recruiting participants now
- 55%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Massachusetts General Hospital
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Observational Pharmaco-Epidemiology Research & Analysis
Epividian
NCT03813862
The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing
University of Chicago
NCT01280825
Registry and Biorepository for IBD in Central Texas
University of Texas at Austin
NCT04617184
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Spyre Therapeutics
NCT07012395
Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease
Montefiore Medical Center
NCT06266663
The Effect of IBD Flares on Serum PSA
Northwestern University
NCT03558048
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
NCT06226883
Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
Seattle Children's Hospital
NCT06315179
Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease
NYU Langone Health
NCT06309017
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Eli Lilly and Company
NCT04844606
BOOM-IBD2 Pivotal Clinical Trial
Boomerang Medical
NCT06571669
Heart Rate Variability and Inflammatory Bowel Disease
Emory University
NCT06537258
Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease
Weill Medical College of Cornell University
NCT06274554
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy
Children's Hospital Medical Center, Cincinnati
NCT03847467
Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility
Massachusetts General Hospital
NCT05332639
IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
University of Michigan
NCT06094608
Feasibility Test of Action Planning in Pediatric IBD
University of North Carolina, Chapel Hill
NCT06186752
Therapeutic Endpoint in Pediatric IBD Conditions
Children's National Research Institute
NCT06065228
Regulation of Mucosal Healing in Inflammatory Bowel Disease
Terrence A Barrett
NCT04504136
Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients
University of Michigan
NCT06188793
Outpatient VR (Virtual Reality)-Brain-gut Behavioral Therapies (BGBT) in Inflammatory Bowel Disease (IBD)
University of Michigan
NCT06910787
A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule
Massachusetts General Hospital
NCT07219537
VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems
University of Louisville
NCT03953768
Fermented Food-Supplemented Diet in Ulcerative Colitis
Stanford University
NCT04401605
Beta-Hydroxybutyrate Feasibility Treating IBD
University of Texas at Austin
NCT06351124
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
Stanford University
NCT05912387
Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance
Massachusetts General Hospital
NCT07033208
A 5-year Longitudinal Observational Study of Patients Undergoing Therapy for Inflammatory Bowel Disease
Target PharmaSolutions
NCT03251118
A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease
Janssen Biotech
NCT00606346
A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
NCT05611671
Proactive Infliximab Optimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patients With Inflammatory Bowel Disease: The OPTIMIZE Trial
Beth Israel Deaconess Medical Center
NCT04835506
A Novel Remote Patient and Medication Monitoring Solution to Improve Adherence and PerSiStence With IBD Therapy
University of Maryland, Baltimore
NCT05316584
Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe
Massachusetts General Hospital
NCT04565821
A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
Janssen Research & Development
NCT02407236
Monitoring Serologic Response to Severe Acute Respiratory Syndrome-2 (SARS-COV-2)/COVID-19 in Children
Connecticut Children's Medical Center
NCT04838834
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions
Duke University
NCT03938324
The Deep South Surgical Equity Research Network: Addressing Socioecological Determinants of Health
University of Alabama at Birmingham
NCT05345054
Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®)
Cedars-Sinai Medical Center
NCT03723447
Cytokines and Genes in Therapeutic Response in Crohn's Disease
Vanderbilt University Medical Center
NCT03266471
Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System
Capso Vision
NCT04573959
Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease
Dartmouth-Hitchcock Medical Center
NCT03799471
Multiple Dose Ethnobridging PK Study in Healthy Subjects
Theravance Biopharma
NCT03750565
A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease
University of Washington
NCT05651542
A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet Formulation
Bristol-Myers Squibb
NCT03254784
SMART-IBD App Trial
Children's Hospital Medical Center, Cincinnati
NCT06023667
Health Coaching as a Tool for Improving Medication Adherence in Adult Patients With Inflammatory Bowel Disease
Vanderbilt University Medical Center
NCT03757533
Examining the Effect of Ondansetron on Bowel Prep Success
State University of New York - Downstate Medical Center
NCT05439772
Digital Behavioral Interventions in Inflammatory Bowel Disease
Montefiore Medical Center
NCT04861597
Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's Colitis
Stacy A. Kahn
NCT02330653
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 3 |
| Phase 3 | 3 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Inflammatory Bowel Diseases Trial Landscape
ClinicalTrials.gov lists 49 US studies indexed under Inflammatory Bowel Diseases, and 27 of those are currently open to recruitment — roughly 55% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Inflammatory Bowel Diseases shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 9 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Inflammatory Bowel Diseases is led by Massachusetts General Hospital with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 49 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Inflammatory Bowel Diseases?
PlainTrial tracks 49 US clinical trials for Inflammatory Bowel Diseases, of which 27 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Inflammatory Bowel Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.