Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04504136 · ClinicalTrials.gov registry record · NA
Regulation of Mucosal Healing in Inflammatory Bowel Disease
A NA study of Inflammatory Bowel Diseases, sponsored by Terrence A Barrett.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT04504136: Recruiting NA study of Inflammatory Bowel Diseases, sponsored by Terrence A Barrett.
NCT04504136 is a NA study of Inflammatory Bowel Diseases that is actively recruiting participants, run by Terrence A Barrett. The registered enrollment target is 60 participants, below the 42,260-participant average among 48 other Inflammatory Bowel Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04504136, a NA study of Inflammatory Bowel Diseases, is actively recruiting participants, sponsored by Terrence A Barrett.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of the current study is to compare non-healing colonic ulcers in patients with inflammatory bowel disease (IBD) with iatrogenic colonic ulcers (biopsy sites) in healthy control patients and patients with rheumatoid or psoriatic arthritis. Patients will be biopsied at baseline and again at a follow-up visit in a "biopsy of the biopsy" approach. These biopsies will be used to reveal patterns about gene expression and mitochondrial function during ulcer healing.
Primary Outcome
Mitochondrial DNA copy number will be measured in epithelial cells collected from biopsies taken during the initial colonoscopy and at the follow-up colonoscopy.
Conditions Studied
Interventions
- PROCEDURE Serial Biopsy
Study Locations (1)
Kentucky
- University of Kentucky - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2021-04-30 |
| Est. Completion | 2026-06-01 |
| Phase | NA |
What NCT04504136 shows while recruiting
NCT04504136 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 42,260-participant average among 48 other Inflammatory Bowel Diseases trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Inflammatory Bowel Diseases appearing as the primary indexed condition, and to 1 intervention - of which Serial Biopsy is the first listed.
NCT04504136 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT04504136 about?
NCT04504136 is a clinical study titled "Regulation of Mucosal Healing in Inflammatory Bowel Disease". The objective of the current study is to compare non-healing colonic ulcers in patients with inflammatory bowel disease (IBD) with iatrogenic colonic ulcers (biopsy sites) in healthy control patients and patients with rheumatoid or psoriatic arthritis. Patients will be biopsied at baseline and again...
What is the current status of trial NCT04504136?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2021-04-30. Estimated completion is 2026-06-01.
What conditions does trial NCT04504136 study?
This clinical trial studies the following conditions: Inflammatory Bowel Diseases.
What interventions are being tested in trial NCT04504136?
The interventions under investigation include: Serial Biopsy (PROCEDURE).
Who is sponsoring clinical trial NCT04504136?
This trial is sponsored by Terrence A Barrett, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04504136 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Inflammatory Bowel Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04504136's enrollment target sits among peer trials
60 30th of 48 higher than 16 of 48 other Inflammatory Bowel Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Inflammatory Bowel Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease
RECRUITING · NA
-
Feasibility Test of Action Planning in Pediatric IBD
RECRUITING · NA
-
Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance
RECRUITING · NA
-
Fermented Food-Supplemented Diet in Ulcerative Colitis
RECRUITING · NA
-
Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility
RECRUITING · NA
-
BOOM-IBD2 Pivotal Clinical Trial
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00576069 · 60 participants
Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
- NCT01297400 · 60 participants · Phase 2
Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns
- NCT01734122 · 60 participants
Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor
- NCT01804634 · 60 participants · Phase 2
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI