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NCT05912387 · ClinicalTrials.gov registry record · Early Phase 1
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
A Early Phase 1 study of Inflammatory Bowel Diseases and Primary Sclerosing Cholangitis, sponsored by Stanford University.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT05912387: Recruiting Early Phase 1 study of Inflammatory Bowel Diseases and Primary Sclerosing Cholangitis, sponsored by Stanford University.
NCT05912387 is a Early Phase 1 study of Inflammatory Bowel Diseases and Primary Sclerosing Cholangitis that is actively recruiting participants, run by Stanford University. The registered enrollment target is 15 participants, below the 42,261-participant average among 48 other Inflammatory Bowel Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05912387, a Early Phase 1 study of Inflammatory Bowel Diseases and Primary Sclerosing Cholangitis, is actively recruiting participants, sponsored by Stanford University.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection. Additionally, many patients require a liver transplant. Progress towards a cure has been severely limited by an incomplete understanding of why patients develop PSC. The investigators aim to close this gap by conducting a pilot human study in patients with PSC, using statin therapy as a model
Primary Outcome
BA profile of biliary/intestinal aspirate and/or feces in response to statin therapy.
Conditions Studied
Interventions
- DRUG Rosuvastatin
Study Locations (1)
California
- Stanford University - Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2023-05-31 |
| Est. Completion | 2027-12-31 |
| Phase | Early Phase 1 |
What NCT05912387 shows while recruiting
NCT05912387 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 42,261-participant average among 48 other Inflammatory Bowel Diseases trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Inflammatory Bowel Diseases appearing as the primary indexed condition, and to 1 intervention - of which Rosuvastatin is the first listed.
NCT05912387 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05912387 about?
NCT05912387 is a clinical study titled "Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study". PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection. Additionally, many patients require a liver transplant. Progress towards a cure has been severely limited by an incomplete understanding of why patients develop PSC. The invest...
What is the current status of trial NCT05912387?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2023-05-31. Estimated completion is 2027-12-31.
What conditions does trial NCT05912387 study?
This clinical trial studies the following conditions: Inflammatory Bowel Diseases, Primary Sclerosing Cholangitis.
What interventions are being tested in trial NCT05912387?
The interventions under investigation include: Rosuvastatin (DRUG).
Who is sponsoring clinical trial NCT05912387?
This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05912387 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05912387's enrollment target sits among peer trials
15 46th of 48 higher than 1 of 48 other Inflammatory Bowel Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Inflammatory Bowel Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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