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NCT03799471 · ClinicalTrials.gov registry record

Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease

A clinical trial of Chronic Pain and Inflammatory Bowel Diseases, sponsored by Dartmouth-Hitchcock Medical Center.

Completed
Registry status
77
Enrollment target
1
Study location

NCT03799471: Completed study of Chronic Pain and Inflammatory Bowel Diseases, sponsored by Dartmouth-Hitchcock Medical Center.

NCT03799471 is a study of Chronic Pain and Inflammatory Bowel Diseases that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 77 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03799471, a study of Chronic Pain and Inflammatory Bowel Diseases, has completed, sponsored by Dartmouth-Hitchcock Medical Center.

COMPLETED
Registry status
77 participants
Enrollment target
1
Study location

Study Summary

This study evaluates nervous system hypersensitivity in individuals with inflammatory bowel disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain. Previous results and current literature suggest that MSK pain in IBD may be influenced by hypersensitivity of the central nervous system, termed central sensitization. However, specific mechanisms contributing to pain experiences are unknown. Therefore, primary aims are to explore aspects of central sensitization through sensory testing in this population, and to investigate association of psychological and IBD features to sensory profiles. This study hypothesizes that IBD patients with MSK pain will demonstrate altered sensory function, and IBD/psychosocial features will be associated with altered sensory functioning and worse pain experiences.

Primary Outcome

PPT will be assessed using an electronic handheld algometer (Wagner Force One™ FDIX) in: 1) low back (local), and 2) contralateral tibialis anterior. Individuals in "IBD with MSK pain" group will undergo an additional PPT assessment related to the region identified as their "main" area of MSK pain. PPT will be assessed by a series of 3 ascending stimulus intensities given as a slowly increasing ramp (50 kilopascal (kPa/s)) from 0 to a maximum pressure of 1000 kPa. Pressure corresponding to the

Study Locations (1)

New Hampshire

  • Dartmouth-Hitchcock Medical Center - Lebanon

Trial Details

FieldValue
Enrollment Target 77 participants
Start Date 2019-02-26
Est. Completion 2019-07-19
Dartmouth-Hitchcock Medical Center

427 total trials

What the finished NCT03799471 record still lists

NCT03799471 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 77 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (90% lower).

The record links to 3 conditions, with Chronic Pain appearing as the primary indexed condition, and to 0 interventions.

NCT03799471 reports a single indexed study location in New Hampshire.

Frequently Asked Questions

What is clinical trial NCT03799471 about?

NCT03799471 is a clinical study titled "Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease". This study evaluates nervous system hypersensitivity in individuals with inflammatory bowel disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain. Previous results and current literature suggest that MSK pain in IBD may be influenced by hypersensitivity of the central nervous system, t...

What is the current status of trial NCT03799471?

This trial is currently completed. The enrollment target is 77 participants. The study started on 2019-02-26. Estimated completion is 2019-07-19.

What conditions does trial NCT03799471 study?

This clinical trial studies the following conditions: Chronic Pain, Inflammatory Bowel Diseases, Central Sensitization.

Who is sponsoring clinical trial NCT03799471?

This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03799471 being conducted?

This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Chronic Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03799471's enrollment target sits among peer trials

77 156th of 301 higher than 146 of 301 other Chronic Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03799471, the US trial registry maintained by the National Library of Medicine. NCT03799471 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.