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NCT06274554 · ClinicalTrials.gov registry record · Phase 3

Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

A Phase 3 study of Crohn's Disease and Inflammatory Bowel Diseases, sponsored by Weill Medical College of Cornell University.

Recruiting
Registry status
Phase 3
Development phase
120
Enrollment target
1
Study location

NCT06274554 is a Phase 3 study of Crohn's Disease and Inflammatory Bowel Diseases that is actively recruiting participants, run by Weill Medical College of Cornell University. The registered enrollment target is 120 participants, below the 2,414-participant average among 104 other Crohn's Disease trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06274554, a Phase 3 study of Crohn's Disease and Inflammatory Bowel Diseases, is actively recruiting participants, sponsored by Weill Medical College of Cornell University.

RECRUITING
Registry status
Phase 3
Development phase
120 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn about the effects of fluconazole in patients who plan to start or are currently undergoing standard of care treatment and plan to dose-escalate an IL-23 therapy for their Crohn's disease. The main question it aims to assess is whether or not patient response to IL-23 therapies improve when simultaneously treated with fluconazole.

Interventions

  • DRUG Placebo
  • DRUG Fluconazole
  • BIOLOGICAL IL-23 Therapy

Study Locations (1)

New York

  • Weill Cornell Medicine - New York

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2024-10-04
Est. Completion 2029-12
Phase Phase 3

What the Registry Record Tells You About NCT06274554

The ClinicalTrials.gov registry entry for NCT06274554 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,414-participant average among 104 other Crohn's Disease trials with a reported enrollment target (95% lower). The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Crohn's Disease appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06274554 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06274554 about?

NCT06274554 is a clinical study titled "Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease". The goal of this clinical trial is to learn about the effects of fluconazole in patients who plan to start or are currently undergoing standard of care treatment and plan to dose-escalate an IL-23 therapy for their Crohn's disease. The main question it aims to assess is whether or not patient respo...

What is the current status of trial NCT06274554?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 120 participants. The study started on 2024-10-04. Estimated completion is 2029-12.

What conditions does trial NCT06274554 study?

This clinical trial studies the following conditions: Crohn's Disease, Inflammatory Bowel Diseases.

What interventions are being tested in trial NCT06274554?

The interventions under investigation include: Placebo (DRUG), Fluconazole (DRUG), IL-23 Therapy (BIOLOGICAL).

Who is sponsoring clinical trial NCT06274554?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06274554 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.