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2026 data Public-data reference. official source

Infections

Open-data reference.

27 US clinical trials · 18 currently recruiting

Active & Recent Trials

RECRUITING NA 33,183 participants

EnCoRe MoMS: Engaging Communities to Reduce Morbidity From Maternal Sepsis (Aim 1)

Columbia University

NCT06145724

RECRUITING 20,000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Exactech

NCT05603728

RECRUITING Phase 3 4,514 participants

Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections

Ondine Biomedical

NCT06702878

RECRUITING NA 750 participants

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

Hebrew SeniorLife

NCT05950607

RECRUITING 600 participants

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00006150

RECRUITING Phase 2 600 participants

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

BioAegis Therapeutics

NCT05947955

RECRUITING Phase 1 400 participants

Azithromycin Before Induction

Arrowhead Regional Medical Center

NCT06543290

RECRUITING NA 300 participants

TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections

Inflammatix

NCT06637904

RECRUITING NA 260 participants

Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention

University of Maryland, Baltimore

NCT06002685

RECRUITING Phase 3 250 participants

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Major Extremity Trauma Research Consortium

NCT05699174

RECRUITING NA 200 participants

CIED Infection Quality Initiative Demonstration Project

Duke University

NCT05471973

RECRUITING 150 participants

Remote Sputum Collection in Cystic Fibrosis

University of Pennsylvania

NCT06950892

RECRUITING 150 participants

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

International Consortium of Circulatory Assist Clinicians

NCT06039176

RECRUITING NA 100 participants

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

University of Missouri-Columbia

NCT05846438

RECRUITING Phase 4 40 participants

Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty

The Methodist Hospital Research Institute

NCT06384651

RECRUITING NA 25 participants

Augmented Reality For MRI-Guided Interventions

Children's National Research Institute

NCT06224933

RECRUITING Phase 1 20 participants

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00967785

RECRUITING 16 participants

X-linked Moesin Associated Immunodeficiency

Institut National de la Santé Et de la Recherche Médicale, France

NCT06278337

ACTIVE NOT RECRUITING NA 25,874 participants

Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 (VITAL Infection)

Brigham and Women's Hospital

NCT01758081

ACTIVE NOT RECRUITING Phase 2 21 participants

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

National Cancer Institute (NCI)

NCT05797246

COMPLETED Phase 4 498 participants

Xofluza-Wearables Feasibility-Study

Children's Hospital of Philadelphia

NCT06161454

COMPLETED 330 participants

Brain Deficits in HIV/HCV Coinfected People Before and After Anti-HCV Therapy

University of California, Los Angeles

NCT00747539

COMPLETED NA 200 participants

Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?

Jewish Hospital, Cincinnati, Ohio

NCT01878968

COMPLETED Phase 4 53 participants

Study of Blood Levels of Ceftaroline Fosamil in Children Who Are Receiving Antibiotic Therapy in the Hospital

Forest Laboratories

NCT01298843

COMPLETED Phase 1 31 participants

Safety, Tolerability and Pharmacokinetics of Single Dose Intravenous Moxifloxacin in Pediatric Patients

Bayer

NCT01049022

COMPLETED Phase 1 12 participants

The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers

Rutgers, The State University of New Jersey

NCT01064986

COMPLETED 8 participants

Cerebrospinal Fluid (CSF) Pharmacokinetics of Antimicrobials in Children

Duke University

NCT00991185

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 2
Phase 3 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Infections Trial Landscape

ClinicalTrials.gov lists 27 US studies indexed under Infections, and 18 of those are currently open to recruitment — roughly 67% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Infections shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Infections is led by National Institute of Allergy and Infectious Diseases (NIAID) with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Infections?

PlainTrial tracks 27 US clinical trials for Infections, of which 18 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Infections?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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