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NCT06702878 · ClinicalTrials.gov registry record · Phase 3
Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections
A Phase 3 study of Infections and Surgical Wound Infection, sponsored by Ondine Biomedical.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 4,514
- Enrollment target
- 14
- Study locations
NCT06702878: Recruiting Phase 3 study of Infections and Surgical Wound Infection, sponsored by Ondine Biomedical.
NCT06702878 is a Phase 3 study of Infections and Surgical Wound Infection that is actively recruiting participants, run by Ondine Biomedical. The registered enrollment target is 4,514 participants, above the 3,234-participant average among 26 other Infections trials with a reported enrollment target (40% higher). The trial reports 14 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06702878, a Phase 3 study of Infections and Surgical Wound Infection, is actively recruiting participants, sponsored by Ondine Biomedical.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 4,514 participants
- Enrollment target
- 14
- Study locations
Study Summary
This is a Phase 3 multi-center, group-randomized, crossover trial to compare nasal antimicrobial photodisinfection therapy (aPDT) with standard of care for prevention of surgical site infections in patients undergoing major elective, urgent, or emergent surgeries in a hospital setting. The main outcomes are to: 1. compare the efficacy, and 2. estimate the safety of applying nasal (aPDT) before surgery in reducing the incidence of SSIs within the initial 30 days after surgery compared to standard of care (SOC). Participants in the intervention group will receive aPDT prior to surgery on the day of surgery. Participants in the control group will receive standard of care surgical site prevention measures prior to surgery.
Conditions Studied
Interventions
- COMBINATION_PRODUCT nasal antimicrobial photodisinfection therapy
Study Locations (14)
Texas
- Medical City Frisco Hospital - Frisco
- HCA Houston Healthcare Kingwood - Kingwood
- Medical City Plano - Plano
- Methodist Metropolitan Hospital - San Antonio
- Methodist Main Hospital and Landmark - San Antonio
- Methodist Stone Oak - San Antonio
- HCA Houston Healthcare Clear Lake Hospital - Webster
Florida
- HCA Brandon Florida - Brandon
- HCA Florida Largo Hospital - Largo
- HCA Florida NorthSide Hospital - St. Petersburg
- HCA Florida Trinity Hospital - Trinity
Colorado
- Swedish Medical Center - Englewood
Tennessee
- Centennial Medical Center - Nashville
Virginia
- Johnston Willis Hospital - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4,514 participants |
| Start Date | 2024-12-27 |
| Est. Completion | 2026-04-30 |
| Phase | Phase 3 |
What NCT06702878 shows while recruiting
NCT06702878 is an interventional study that assigns participants to a tested intervention. Its 4,514 participants enrollment target places it among the larger protocols in the corpus, above the 3,234-participant average among 26 other Infections trials with a reported enrollment target (40% higher).
The record links to 4 conditions, with Infections appearing as the primary indexed condition, and to 1 intervention - of which nasal antimicrobial photodisinfection therapy is the first listed.
NCT06702878 lists 14 locations in 5 states (Texas, Florida, Colorado).
Frequently Asked Questions
What is clinical trial NCT06702878 about?
NCT06702878 is a clinical study titled "Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections". This is a Phase 3 multi-center, group-randomized, crossover trial to compare nasal antimicrobial photodisinfection therapy (aPDT) with standard of care for prevention of surgical site infections in patients undergoing major elective, urgent, or emergent surgeries in a hospital setting. The main outc...
What is the current status of trial NCT06702878?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 4,514 participants. The study started on 2024-12-27. Estimated completion is 2026-04-30.
What conditions does trial NCT06702878 study?
This clinical trial studies the following conditions: Infections, Surgical Wound Infection, Surgical Site Infections, Anti-Infective Agents.
What interventions are being tested in trial NCT06702878?
The interventions under investigation include: nasal antimicrobial photodisinfection therapy (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06702878?
This trial is sponsored by Ondine Biomedical, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06702878 being conducted?
This trial has 14 study locations across Colorado, Florida, Tennessee, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Infections
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06702878's enrollment target sits among peer trials
4,514 4th of 26 higher than 23 of 26 other Infections trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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