Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01064986 · ClinicalTrials.gov registry record · Phase 1

The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers

A Phase 1 study of Infections, sponsored by Rutgers, The State University of New Jersey.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target
1
Study location

NCT01064986: Completed Phase 1 study of Infections, sponsored by Rutgers, The State University of New Jersey.

NCT01064986 is a Phase 1 study of Infections that has completed, run by Rutgers, The State University of New Jersey. The registered enrollment target is 12 participants, below the 3,407-participant average among 26 other Infections trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01064986, a Phase 1 study of Infections, has completed, sponsored by Rutgers, The State University of New Jersey.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

Corticosteroids are substances produced by the adrenal gland to help the body fight against infection or injury. Hydrocortisone is a man-made form of this substance. Endotoxin is a man-made substance, which causes the body to "mimic" sickness(fever,chills,and achiness)for a few hours. This study is designed to give hydrocortisone before and after Endotoxin to determine if this medication can prevent or relieve any of the symptoms caused by the Endotoxin.

Conditions Studied

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Endotoxin, Lipopolysaccharide, LPS
  • BIOLOGICAL Endotoxin, Lipopolysaccharide, LPS /Epinephrine
  • BIOLOGICAL Hydrocortisone

Study Locations (1)

New Jersey

  • Rutgers-RWJMS - New Brunswick

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2010-02
Est. Completion 2012-12
Phase Phase 1

What the finished NCT01064986 record still lists

NCT01064986 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 3,407-participant average among 26 other Infections trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Infections appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT01064986 reports a single indexed study location in New Jersey.

Frequently Asked Questions

What is clinical trial NCT01064986 about?

NCT01064986 is a clinical study titled "The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers". Corticosteroids are substances produced by the adrenal gland to help the body fight against infection or injury. Hydrocortisone is a man-made form of this substance. Endotoxin is a man-made substance, which causes the body to "mimic" sickness(fever,chills,and achiness)for a few hours. This study is ...

What is the current status of trial NCT01064986?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2010-02. Estimated completion is 2012-12.

What conditions does trial NCT01064986 study?

This clinical trial studies the following conditions: Infections.

What interventions are being tested in trial NCT01064986?

The interventions under investigation include: Placebo (BIOLOGICAL), Endotoxin, Lipopolysaccharide, LPS (BIOLOGICAL), Endotoxin, Lipopolysaccharide, LPS /Epinephrine (BIOLOGICAL), Hydrocortisone (BIOLOGICAL).

Who is sponsoring clinical trial NCT01064986?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01064986 being conducted?

This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01064986's enrollment target sits among peer trials

12 26th of 26 higher than 1 of 26 other Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02602769 · 12 participants

    Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

  • NCT02605421 · 12 participants · Phase 2

    Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

  • NCT02619448 · 12 participants · Early Phase 1

    Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

  • NCT03311503 · 12 participants · Phase 1

    Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01064986, the US trial registry maintained by the National Library of Medicine. NCT01064986 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.